STRINGSTRING
EDA EDA LTA LTA TNFRSF17 TNFRSF17 EDARADD EDARADD PSME2 PSME2 PSME1 PSME1 CD40LG CD40LG PSMB5 PSMB5 TNFSF4 TNFSF4 PSMC2 PSMC2 PSMA1 PSMA1 PSMB11 PSMB11 TNFSF14 TNFSF14 CD70 CD70 PSMD10 PSMD10 LOC111166275 LOC111166275 KXD1 KXD1 PSMD3 PSMD3 PSMB3 PSMB3 TNFRSF11B TNFRSF11B PSMB1 PSMB1 BIRC3 BIRC3 TNFSF9 TNFSF9 LOC111166421 LOC111166421 EDA2R EDA2R PSMD13 PSMD13 TNF TNF TNFRSF25 TNFRSF25 PSMD9 PSMD9 PSMA7 PSMA7 TNFRSF6B TNFRSF6B PSME4 PSME4 TNFRSF8 TNFRSF8 TNFRSF4 TNFRSF4 TNFRSF18 TNFRSF18 TNFRSF1B TNFRSF1B PSMB6 PSMB6 TNFSF13 TNFSF13 TNFSF12 TNFSF12 PSMD11 PSMD11 FBXW11 FBXW11 TNFRSF13C TNFRSF13C TNFRSF9 TNFRSF9 TNFRSF12A TNFRSF12A RPS27A RPS27A LOC111185785 LOC111185785 TRAF5 TRAF5 PSMA2 PSMA2 PSMF1 PSMF1 PSMD12 PSMD12 PSMC3 PSMC3 PSMC5 PSMC5 PSMA8 PSMA8 PSMD8 PSMD8 PSMB10 PSMB10 PSMB8 PSMB8 TNFRSF11A TNFRSF11A PSMC4 PSMC4 PSMA4 PSMA4 TNFSF8 TNFSF8 PSMA5 PSMA5 PSMD7 PSMD7 TNFRSF1A TNFRSF1A PSMB7 PSMB7 PSMB9 PSMB9 PSMD5 PSMD5 TNFSF13B TNFSF13B TRAF2 TRAF2 TNFSF15 TNFSF15 CD27 CD27 LTBR LTBR PSMB2 PSMB2 TRAF3 TRAF3 PSMC1 PSMC1 TNFSF11 TNFSF11 NFKB2 NFKB2 PSMD6 PSMD6 CHUK CHUK LTB LTB PSMA3 PSMA3 PSMA6 PSMA6 PSMC6 PSMC6 BTRC BTRC PSMD14 PSMD14 PSMD1 PSMD1 PSMD4 PSMD4 LOC111168369 LOC111168369 CD40 CD40 PSMB4 PSMB4 MAP3K14 MAP3K14 TNFSF18 TNFSF18 TNFRSF13B TNFRSF13B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (391 aa)
LTALymphotoxin-alpha; Belongs to the tumor necrosis factor family. (205 aa)
TNFRSF17Tumor necrosis factor receptor superfamily member 17 isoform X1. (238 aa)
EDARADDectodysplasin-A receptor-associated adapter protein isoform X3. (205 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
PSMB5Proteasome subunit beta. (263 aa)
TNFSF4Tumor necrosis factor ligand superfamily member 4; Belongs to the tumor necrosis factor family. (182 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMB11Proteasome subunit beta. (291 aa)
TNFSF14Tumor necrosis factor ligand superfamily member 14 isoform X1. (241 aa)
CD70CD70 antigen isoform X1; Belongs to the tumor necrosis factor family. (298 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC111166275Proteasome activator complex subunit 3-like. (165 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (196 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)
PSMB1Proteasome subunit beta. (241 aa)
BIRC3Baculoviral IAP repeat-containing protein 3 isoform X1. (604 aa)
TNFSF9Tumor necrosis factor ligand superfamily member 9; Belongs to the tumor necrosis factor family. (252 aa)
LOC111166421Proteasome activator complex subunit 3. (254 aa)
EDA2RTumor necrosis factor receptor superfamily member 27 isoform X1. (364 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
TNFRSF25Tumor necrosis factor receptor superfamily member 25 isoform X1. (419 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
TNFRSF6BTumor necrosis factor receptor superfamily member 6B. (296 aa)
PSME4LOW QUALITY PROTEIN: proteasome activator complex subunit 4. (1845 aa)
TNFRSF8Tumor necrosis factor receptor superfamily member 8. (598 aa)
TNFRSF4Tumor necrosis factor receptor superfamily member 4. (278 aa)
TNFRSF18LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 18. (231 aa)
TNFRSF1BTumor necrosis factor receptor superfamily member 1B. (454 aa)
PSMB6Proteasome subunit beta. (239 aa)
TNFSF13Tumor necrosis factor ligand superfamily member 13 isoform X1; Belongs to the tumor necrosis factor family. (247 aa)
TNFSF12Tumor necrosis factor ligand superfamily member 12 isoform X2; Belongs to the tumor necrosis factor family. (249 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X1. (563 aa)
TNFRSF13CTumor necrosis factor receptor superfamily member 13C isoform X1. (221 aa)
TNFRSF9Tumor necrosis factor receptor superfamily member 9. (260 aa)
TNFRSF12ATumor necrosis factor receptor superfamily member 12A. (129 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC111185785Baculoviral IAP repeat-containing protein 1 isoform X1. (1759 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
PSMA8Proteasome subunit alpha type. (269 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB8Proteasome subunit beta. (276 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A isoform X1. (551 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
TNFSF8Tumor necrosis factor ligand superfamily member 8 isoform X1; Belongs to the tumor necrosis factor family. (234 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (445 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
TNFSF13BTumor necrosis factor ligand superfamily member 13B; Belongs to the tumor necrosis factor family. (283 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
TNFSF15Tumor necrosis factor ligand superfamily member 15. (256 aa)
CD27CD27 antigen isoform X1. (251 aa)
LTBRTumor necrosis factor receptor superfamily member 3. (421 aa)
PSMB2Proteasome subunit beta. (201 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit isoform X1. (900 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
LTBLymphotoxin-beta; Belongs to the tumor necrosis factor family. (247 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (607 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
LOC111168369Baculoviral IAP repeat-containing protein 2. (620 aa)
CD40Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14 isoform X1. (961 aa)
TNFSF18Tumor necrosis factor ligand superfamily member 18. (178 aa)
TNFRSF13BTumor necrosis factor receptor superfamily member 13B isoform X1. (284 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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