STRINGSTRING
CDC6 CDC6 PSMD9 PSMD9 PSMA7 PSMA7 SKP2 SKP2 PSME4 PSME4 MCM5 MCM5 PSMB6 PSMB6 PSMD11 PSMD11 RPS27A RPS27A RBX1 RBX1 PSMA2 PSMA2 CCNA2 CCNA2 PSMF1 PSMF1 PSMD12 PSMD12 PSMC3 PSMC3 SKP1 SKP1 MCM7 MCM7 PSMC5 PSMC5 CDK3 CDK3 PSMA8 PSMA8 PSMD8 PSMD8 PSMB10 PSMB10 MCM3 MCM3 PSMB8 PSMB8 PSMC4 PSMC4 PSMA4 PSMA4 PSMA5 PSMA5 CDT1 CDT1 PSMD7 PSMD7 PSMB7 PSMB7 PSMB9 PSMB9 PSMD5 PSMD5 CUL1 CUL1 ORC1 ORC1 PSMB2 PSMB2 CCNA1 CCNA1 PSMC1 PSMC1 MCM6 MCM6 PSMD6 PSMD6 CDK2 CDK2 TM4SF19 TM4SF19 PSMA3 PSMA3 PSMA6 PSMA6 PSMC6 PSMC6 PSMD14 PSMD14 ORC4 ORC4 PSMD1 PSMD1 PSMD4 PSMD4 MCM2 MCM2 ORC2 ORC2 PSMB4 PSMB4 PSMD13 PSMD13 LOC111166421 LOC111166421 PSMB1 PSMB1 MCM4 MCM4 PSMB3 PSMB3 PSMD3 PSMD3 ORC5 ORC5 KXD1 KXD1 LOC111166275 LOC111166275 MCM9 MCM9 PSMD10 PSMD10 MCM8 MCM8 PSMB11 PSMB11 ORC6 ORC6 PSMA1 PSMA1 PSMC2 PSMC2 PSMB5 PSMB5 PSME1 PSME1 PSME2 PSME2 ORC3 ORC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (647 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
SKP2S-phase kinase-associated protein 2 isoform X1. (436 aa)
PSME4LOW QUALITY PROTEIN: proteasome activator complex subunit 4. (1845 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (432 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
SKP1S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (164 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
CDK3Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily. (360 aa)
PSMA8Proteasome subunit alpha type. (269 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
PSMB10Proteasome subunit beta. (273 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
PSMB8Proteasome subunit beta. (276 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
CDT1DNA replication factor Cdt1. (551 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa)
PSMB2Proteasome subunit beta. (201 aa)
CCNA1cyclin-A1; Belongs to the cyclin family. (421 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
TM4SF19Transmembrane 4 L6 family member 19. (202 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
ORC2Origin recognition complex subunit 2. (578 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
LOC111166421Proteasome activator complex subunit 3. (254 aa)
PSMB1Proteasome subunit beta. (241 aa)
MCM4DNA helicase; Belongs to the MCM family. (836 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (196 aa)
LOC111166275Proteasome activator complex subunit 3-like. (165 aa)
MCM9DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1144 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
MCM8DNA helicase MCM8; Belongs to the MCM family. (832 aa)
PSMB11Proteasome subunit beta. (291 aa)
ORC6Origin recognition complex subunit 6. (273 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
ORC3Origin recognition complex subunit 3 isoform X1. (713 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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