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| | PSME4 | LOW QUALITY PROTEIN: proteasome activator complex subunit 4. (1845 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa) |
| | RFC5 | Replication factor C subunit 5. (340 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (755 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1 isoform X1. (1944 aa) |
| | UBE2C | Ubiquitin-conjugating enzyme E2 C isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (203 aa) |
| | LOC111166421 | Proteasome activator complex subunit 3. (254 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | POLA1 | DNA polymerase. (1468 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (836 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | FZR1 | Fizzy-related protein homolog isoform X1. (496 aa) |
| | KXD1 | kxDL motif-containing protein 1 isoform X1. (196 aa) |
| | LOC111166275 | Proteasome activator complex subunit 3-like. (165 aa) |
| | MCM9 | DNA helicase MCM9 isoform X1; Belongs to the MCM family. (1144 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (647 aa) |
| | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MCM8 | DNA helicase MCM8; Belongs to the MCM family. (832 aa) |
| | PSMB11 | Proteasome subunit beta. (291 aa) |
| | GINS3 | DNA replication complex GINS protein PSF3. (216 aa) |
| | ORC6 | Origin recognition complex subunit 6. (273 aa) |
| | PSMA1 | Proteasome subunit alpha type. (263 aa) |
| | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSME1 | Proteasome activator complex subunit 1. (249 aa) |
| | PSME2 | Proteasome activator complex subunit 2. (239 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform X1. (713 aa) |
| | FAM89A | Protein FAM89A. (178 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa) |
| | GMNN | Geminin. (210 aa) |
| | ANAPC15 | Anaphase-promoting complex subunit 15 isoform X1. (125 aa) |
| | LOC111171144 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (310 aa) |
| | ORC2 | Origin recognition complex subunit 2. (578 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (903 aa) |
| | POLE4 | DNA polymerase epsilon subunit 4 isoform X1. (116 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa) |
| | PSMC6 | 26S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (190 aa) |
| | RFC1 | Replication factor C subunit 1. (1146 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19. (202 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa) |
| | PRIM1 | DNA primase small subunit. (94 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1 isoform X2. (549 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | CDC16 | Cell division cycle protein 16 homolog isoform X1. (620 aa) |
| | RCBTB2 | RCC1 and BTB domain-containing protein 2 isoform X1. (572 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (820 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (863 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (776 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5. (504 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (147 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | BICRAL | BRD4-interacting chromatin-remodeling complex-associated protein-like. (1079 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (322 aa) |
| | CDT1 | DNA replication factor Cdt1. (551 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (524 aa) |
| | PSMB8 | Proteasome subunit beta. (276 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa) |
| | RPA3 | Replication protein A 14 kDa subunit isoform X1. (121 aa) |
| | CCNE1 | G1/S-specific cyclin-E1 isoform X1; Belongs to the cyclin family. (410 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | UBE2S | Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | POLD1 | DNA polymerase. (1107 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | PSMA8 | Proteasome subunit alpha type. (269 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11. (84 aa) |
| | LIG1 | DNA ligase. (922 aa) |
| | CDK3 | Cyclin-dependent kinase 3 isoform X3; Belongs to the protein kinase superfamily. (360 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1. (1097 aa) |
| | LOC111183680 | DNA polymerase delta subunit 4. (182 aa) |
| | FAM89B | Protein FAM89B. (192 aa) |
| | SKP1 | S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (164 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (597 aa) |
| | CDC27 | Cell division cycle protein 27 homolog isoform X1. (837 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (599 aa) |
| | PSMC3 | 26S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (456 aa) |
| | POLD2 | DNA polymerase delta subunit 2 isoform X1. (506 aa) |
| | ANAPC16 | Anaphase-promoting complex subunit 16. (109 aa) |
| | POLD3 | DNA polymerase delta subunit 3 isoform X1. (464 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein isoform X1. (471 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit isoform X1. (270 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | RPS27A | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | GINS1 | DNA replication complex GINS protein PSF1 isoform X1. (206 aa) |
| | ANAPC7 | LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (534 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (422 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5 isoform X1. (1898 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X1. (436 aa) |
