48 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMD13	26S proteasome non-ATPase regulatory subunit 13. (376 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
	PSMD4	26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
	PSMC6	26S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	CDK4	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
	PSMC1	26S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	PSMD5	26S proteasome non-ATPase regulatory subunit 5. (504 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PSMD7	26S proteasome non-ATPase regulatory subunit 7. (322 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	PSMC4	26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	PSMD8	26S proteasome non-ATPase regulatory subunit 8. (351 aa)
	PSMA8	Proteasome subunit alpha type. (269 aa)
	PSMC5	26S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
	CCND1	G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
	PSMC3	26S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
	PSMD12	26S proteasome non-ATPase regulatory subunit 12. (456 aa)
	PSMF1	Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
	PSMA2	Proteasome subunit alpha type. (234 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (422 aa)
	PSMB6	Proteasome subunit beta. (239 aa)
	PSME4	LOW QUALITY PROTEIN: proteasome activator complex subunit 4. (1845 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	PSMD9	26S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
	PSME2	Proteasome activator complex subunit 2. (239 aa)
	PSME1	Proteasome activator complex subunit 1. (249 aa)
	PSMB5	Proteasome subunit beta. (263 aa)
	PSMC2	26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	PSMA1	Proteasome subunit alpha type. (263 aa)
	PSMB11	Proteasome subunit beta. (291 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
	LOC111166275	Proteasome activator complex subunit 3-like. (165 aa)
	KXD1	kxDL motif-containing protein 1 isoform X1. (196 aa)
	PSMD3	26S proteasome non-ATPase regulatory subunit 3. (534 aa)
	PSMB3	Proteasome subunit beta. (205 aa)
	PSMB1	Proteasome subunit beta. (241 aa)
	LOC111166421	Proteasome activator complex subunit 3. (254 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCND1	CDK4	A0A2Y9PNM2	A0A2Y9MY60	G1/S-specific cyclin-D1; Belongs to the cyclin family.	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	0.999
CCND1	PSMD6	A0A2Y9PNM2	A0A2Y9N2C8	G1/S-specific cyclin-D1; Belongs to the cyclin family.	26S proteasome non-ATPase regulatory subunit 6 isoform X1.	0.410
CCND1	PSMD7	A0A2Y9PNM2	A0A2Y9NVK0	G1/S-specific cyclin-D1; Belongs to the cyclin family.	26S proteasome non-ATPase regulatory subunit 7.	0.409
CCND1	RPS27A	A0A2Y9PNM2	A0A2Y9Q1L7	G1/S-specific cyclin-D1; Belongs to the cyclin family.	ubiquitin-40S ribosomal protein S27a.	0.435
CDK4	CCND1	A0A2Y9MY60	A0A2Y9PNM2	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	G1/S-specific cyclin-D1; Belongs to the cyclin family.	0.999
CDK4	PSMA4	A0A2Y9MY60	A0A2Y9P184	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.405
CDK4	PSMA5	A0A2Y9MY60	A0A2Y9NY35	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	Proteasome subunit alpha type.	0.407
CDK4	PSMC1	A0A2Y9MY60	A0A2Y9NAX7	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family.	0.400
CDK4	PSMC4	A0A2Y9MY60	A0A2Y9P2S0	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family.	0.424
CDK4	PSMC5	A0A2Y9MY60	A0A2Y9PG79	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome regulatory subunit 8; Belongs to the AAA ATPase family.	0.401
CDK4	PSMC6	A0A2Y9MY60	A0A2Y9MV22	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family.	0.403
CDK4	PSMD1	A0A2Y9MY60	A0A2Y9MRU9	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.433
CDK4	PSMD10	A0A2Y9MY60	A0A2Y9LUI9	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 10 isoform X1.	0.555
CDK4	PSMD11	A0A2Y9MY60	A0A2Y9Q7A0	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 11.	0.407
CDK4	PSMD12	A0A2Y9MY60	A0A2Y9PQ26	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 12.	0.517
CDK4	PSMD14	A0A2Y9MY60	A0A2Y9MUG8	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 14 isoform X1.	0.432
CDK4	PSMD4	A0A2Y9MY60	A0A2Y9MRQ2	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 4 isoform X1.	0.405
CDK4	PSMD7	A0A2Y9MY60	A0A2Y9NVK0	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	26S proteasome non-ATPase regulatory subunit 7.	0.426
CDK4	RPS27A	A0A2Y9MY60	A0A2Y9Q1L7	Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.	ubiquitin-40S ribosomal protein S27a.	0.541
KXD1	PSMD12	A0A2Y9LWQ6	A0A2Y9PQ26	kxDL motif-containing protein 1 isoform X1.	26S proteasome non-ATPase regulatory subunit 12.	0.409