20 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	MAPK1	Mitogen-activated protein kinase. (380 aa)
	LOC111165935	Ras-like protein isoform X1. (285 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (775 aa)
	GAST	Gastrin. (170 aa)
	CCKBR	Gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (454 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (780 aa)
	ERAS	GTPase ERas. (233 aa)
	CREB1	Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	KRAS	GTPase KRas. (188 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	NRAS	GTPase NRas. (189 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	EGFR	Receptor protein-tyrosine kinase. (1209 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (783 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCKBR	GAST	A0A2Y9M9V6	A0A2Y9M8L6	Gastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family.	Gastrin.	0.999
CREB1	EGFR	A0A2Y9MW12	A0A2Y9Q0F2	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Receptor protein-tyrosine kinase.	0.438
CREB1	MAPK1	A0A2Y9MW12	A0A2Y9LEH4	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Mitogen-activated protein kinase.	0.934
CREB1	MAPK3	A0A2Y9MW12	A0A2Y9PDR5	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.926
CREB1	PRKCA	A0A2Y9MW12	A0A2Y9PID1	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.739
CREB1	RPS6KA1	A0A2Y9MW12	A0A2Y9LFC7	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Ribosomal protein S6 kinase.	0.670
CREB1	RPS6KA2	A0A2Y9MW12	A0A2Y9MHC8	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Ribosomal protein S6 kinase.	0.622
CREB1	RPS6KA3	A0A2Y9MW12	A0A2Y9M3B9	Cyclic AMP-responsive element-binding protein 1 isoform X1.	Ribosomal protein S6 kinase.	0.661
CSDE1	EGFR	A0A2Y9P0H2	A0A2Y9Q0F2	Cold shock domain-containing protein E1 isoform X1.	Receptor protein-tyrosine kinase.	0.500
CSDE1	GRB2	A0A2Y9P0H2	A0A2Y9PJ90	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2.	0.565
CSDE1	SOS1	A0A2Y9P0H2	A0A2Y9N647	Cold shock domain-containing protein E1 isoform X1.	Son of sevenless homolog 1 isoform X1.	0.607
EGFR	CREB1	A0A2Y9Q0F2	A0A2Y9MW12	Receptor protein-tyrosine kinase.	Cyclic AMP-responsive element-binding protein 1 isoform X1.	0.438
EGFR	CSDE1	A0A2Y9Q0F2	A0A2Y9P0H2	Receptor protein-tyrosine kinase.	Cold shock domain-containing protein E1 isoform X1.	0.500
EGFR	ERAS	A0A2Y9Q0F2	A0A2Y9MKI3	Receptor protein-tyrosine kinase.	GTPase ERas.	0.511
EGFR	GRB2	A0A2Y9Q0F2	A0A2Y9PJ90	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2.	0.999
EGFR	HBEGF	A0A2Y9Q0F2	A0A2Y9PFK7	Receptor protein-tyrosine kinase.	Proheparin-binding EGF-like growth factor.	0.999
EGFR	HRAS	A0A2Y9Q0F2	A0A2Y9MGR2	Receptor protein-tyrosine kinase.	GTPase HRas isoform X1.	0.982
EGFR	KRAS	A0A2Y9Q0F2	A0A2Y9NF08	Receptor protein-tyrosine kinase.	GTPase KRas.	0.987
EGFR	LOC111165935	A0A2Y9Q0F2	A0A2Y9LSR3	Receptor protein-tyrosine kinase.	Ras-like protein isoform X1.	0.743
EGFR	NRAS	A0A2Y9Q0F2	A0A2Y9PBA0	Receptor protein-tyrosine kinase.	GTPase NRas.	0.982