6 items (Delphinapterus leucas) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	MET	Hepatocyte growth factor receptor isoform X1. (1382 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	GAB1	GRB2-associated-binding protein 1 isoform X1. (757 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAB1	GRB2	A0A2Y9QCZ2	A0A2Y9PJ90	GRB2-associated-binding protein 1 isoform X1.	Growth factor receptor-bound protein 2.	0.999
GAB1	HGF	A0A2Y9QCZ2	A0A2Y9LK73	GRB2-associated-binding protein 1 isoform X1.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.651
GAB1	MET	A0A2Y9QCZ2	A0A2Y9NWP7	GRB2-associated-binding protein 1 isoform X1.	Hepatocyte growth factor receptor isoform X1.	0.993
GAB1	PIK3CA	A0A2Y9QCZ2	A0A2Y9MZW2	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.954
GAB1	PIK3R1	A0A2Y9QCZ2	A0A2Y9Q8T5	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.986
GRB2	GAB1	A0A2Y9PJ90	A0A2Y9QCZ2	Growth factor receptor-bound protein 2.	GRB2-associated-binding protein 1 isoform X1.	0.999
GRB2	HGF	A0A2Y9PJ90	A0A2Y9LK73	Growth factor receptor-bound protein 2.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.565
GRB2	MET	A0A2Y9PJ90	A0A2Y9NWP7	Growth factor receptor-bound protein 2.	Hepatocyte growth factor receptor isoform X1.	0.987
GRB2	PIK3CA	A0A2Y9PJ90	A0A2Y9MZW2	Growth factor receptor-bound protein 2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.665
GRB2	PIK3R1	A0A2Y9PJ90	A0A2Y9Q8T5	Growth factor receptor-bound protein 2.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.940
HGF	GAB1	A0A2Y9LK73	A0A2Y9QCZ2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	GRB2-associated-binding protein 1 isoform X1.	0.651
HGF	GRB2	A0A2Y9LK73	A0A2Y9PJ90	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Growth factor receptor-bound protein 2.	0.565
HGF	MET	A0A2Y9LK73	A0A2Y9NWP7	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor receptor isoform X1.	0.999
HGF	PIK3CA	A0A2Y9LK73	A0A2Y9MZW2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.556
HGF	PIK3R1	A0A2Y9LK73	A0A2Y9Q8T5	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.504
MET	GAB1	A0A2Y9NWP7	A0A2Y9QCZ2	Hepatocyte growth factor receptor isoform X1.	GRB2-associated-binding protein 1 isoform X1.	0.993
MET	GRB2	A0A2Y9NWP7	A0A2Y9PJ90	Hepatocyte growth factor receptor isoform X1.	Growth factor receptor-bound protein 2.	0.987
MET	HGF	A0A2Y9NWP7	A0A2Y9LK73	Hepatocyte growth factor receptor isoform X1.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.999
MET	PIK3CA	A0A2Y9NWP7	A0A2Y9MZW2	Hepatocyte growth factor receptor isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.963
MET	PIK3R1	A0A2Y9NWP7	A0A2Y9Q8T5	Hepatocyte growth factor receptor isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.881