6 items (Delphinapterus leucas) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	MET	Hepatocyte growth factor receptor isoform X1. (1382 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
	LOC111187198	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
	GAB1	GRB2-associated-binding protein 1 isoform X1. (757 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAB1	GRB2	A0A2Y9QCZ2	A0A2Y9PJ90	GRB2-associated-binding protein 1 isoform X1.	Growth factor receptor-bound protein 2.	0.999
GAB1	HGF	A0A2Y9QCZ2	A0A2Y9LK73	GRB2-associated-binding protein 1 isoform X1.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.651
GAB1	LOC111187198	A0A2Y9QCZ2	A0A2Y9QG58	GRB2-associated-binding protein 1 isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.988
GAB1	MET	A0A2Y9QCZ2	A0A2Y9NWP7	GRB2-associated-binding protein 1 isoform X1.	Hepatocyte growth factor receptor isoform X1.	0.993
GAB1	PTPN11	A0A2Y9QCZ2	A0A2Y9QEG1	GRB2-associated-binding protein 1 isoform X1.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.990
GRB2	GAB1	A0A2Y9PJ90	A0A2Y9QCZ2	Growth factor receptor-bound protein 2.	GRB2-associated-binding protein 1 isoform X1.	0.999
GRB2	HGF	A0A2Y9PJ90	A0A2Y9LK73	Growth factor receptor-bound protein 2.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.565
GRB2	LOC111187198	A0A2Y9PJ90	A0A2Y9QG58	Growth factor receptor-bound protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.991
GRB2	MET	A0A2Y9PJ90	A0A2Y9NWP7	Growth factor receptor-bound protein 2.	Hepatocyte growth factor receptor isoform X1.	0.987
GRB2	PTPN11	A0A2Y9PJ90	A0A2Y9QEG1	Growth factor receptor-bound protein 2.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.999
HGF	GAB1	A0A2Y9LK73	A0A2Y9QCZ2	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	GRB2-associated-binding protein 1 isoform X1.	0.651
HGF	GRB2	A0A2Y9LK73	A0A2Y9PJ90	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Growth factor receptor-bound protein 2.	0.565
HGF	LOC111187198	A0A2Y9LK73	A0A2Y9QG58	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.417
HGF	MET	A0A2Y9LK73	A0A2Y9NWP7	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Hepatocyte growth factor receptor isoform X1.	0.999
HGF	PTPN11	A0A2Y9LK73	A0A2Y9QEG1	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.525
LOC111187198	GAB1	A0A2Y9QG58	A0A2Y9QCZ2	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	GRB2-associated-binding protein 1 isoform X1.	0.988
LOC111187198	GRB2	A0A2Y9QG58	A0A2Y9PJ90	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Growth factor receptor-bound protein 2.	0.991
LOC111187198	HGF	A0A2Y9QG58	A0A2Y9LK73	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.417
LOC111187198	MET	A0A2Y9QG58	A0A2Y9NWP7	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Hepatocyte growth factor receptor isoform X1.	0.684
LOC111187198	PTPN11	A0A2Y9QG58	A0A2Y9QEG1	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.902