node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCND1 | CCND2 | A0A2Y9PNM2 | A0A2Y9NG81 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | G1/S-specific cyclin-D2; Belongs to the cyclin family. | 0.935 |
CCND1 | CCND3 | A0A2Y9PNM2 | A0A2Y9NR31 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | 0.938 |
CCND1 | CDK6 | A0A2Y9PNM2 | A0A2Y9P3B0 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | 0.999 |
CCND1 | RUNX1 | A0A2Y9PNM2 | A0A2Y9LIS3 | G1/S-specific cyclin-D1; Belongs to the cyclin family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.538 |
CCND2 | CCND1 | A0A2Y9NG81 | A0A2Y9PNM2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | G1/S-specific cyclin-D1; Belongs to the cyclin family. | 0.935 |
CCND2 | CCND3 | A0A2Y9NG81 | A0A2Y9NR31 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | 0.930 |
CCND2 | CDK6 | A0A2Y9NG81 | A0A2Y9P3B0 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | 0.999 |
CCND2 | RUNX1 | A0A2Y9NG81 | A0A2Y9LIS3 | G1/S-specific cyclin-D2; Belongs to the cyclin family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.473 |
CCND3 | CCND1 | A0A2Y9NR31 | A0A2Y9PNM2 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | G1/S-specific cyclin-D1; Belongs to the cyclin family. | 0.938 |
CCND3 | CCND2 | A0A2Y9NR31 | A0A2Y9NG81 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | G1/S-specific cyclin-D2; Belongs to the cyclin family. | 0.930 |
CCND3 | CDK6 | A0A2Y9NR31 | A0A2Y9P3B0 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | 0.999 |
CCND3 | RUNX1 | A0A2Y9NR31 | A0A2Y9LIS3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.473 |
CDK6 | CCND1 | A0A2Y9P3B0 | A0A2Y9PNM2 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | G1/S-specific cyclin-D1; Belongs to the cyclin family. | 0.999 |
CDK6 | CCND2 | A0A2Y9P3B0 | A0A2Y9NG81 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | G1/S-specific cyclin-D2; Belongs to the cyclin family. | 0.999 |
CDK6 | CCND3 | A0A2Y9P3B0 | A0A2Y9NR31 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. | 0.999 |
CDK6 | RUNX1 | A0A2Y9P3B0 | A0A2Y9LIS3 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.741 |
LOC111187198 | PTPN11 | A0A2Y9QG58 | A0A2Y9QEG1 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.902 |
LOC111187198 | RUNX1 | A0A2Y9QG58 | A0A2Y9LIS3 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.441 |
PML | RUNX1 | A0A2Y9NS17 | A0A2Y9LIS3 | Protein PML isoform X1. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.929 |
PTPN11 | LOC111187198 | A0A2Y9QEG1 | A0A2Y9QG58 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.902 |