STRINGSTRING
RUNX1 RUNX1 CCND2 CCND2 CCND3 CCND3 PML PML CDK6 CDK6 CCND1 CCND1 TNRC6B TNRC6B PTPN11 PTPN11 LOC111187198 LOC111187198
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa)
PMLProtein PML isoform X1. (861 aa)
CDK6Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
TNRC6BTrinucleotide repeat-containing gene 6B protein isoform X1. (1867 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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