STRINGSTRING
PSMD1 PSMD1 PPARGC1A PPARGC1A PSMD14 PSMD14 PSMC6 PSMC6 PSMA6 PSMA6 PSMA3 PSMA3 PSMD6 PSMD6 PSMC1 PSMC1 PSMB2 PSMB2 HIVEP3 HIVEP3 CUL1 CUL1 PSMD5 PSMD5 PSMB9 PSMB9 PSMB7 PSMB7 RUNX2 RUNX2 PSMD7 PSMD7 PSMA5 PSMA5 PSMA4 PSMA4 PSMC4 PSMC4 PSMB8 PSMB8 HIVEP1 HIVEP1 PSMD8 PSMD8 DLX5 DLX5 PPARGC1B PPARGC1B PSMC5 PSMC5 DLX6 DLX6 SKP1 SKP1 PSMC3 PSMC3 PSMD12 PSMD12 MSX2 MSX2 PSMF1 PSMF1 PSMA2 PSMA2 RBX1 RBX1 RPS27A RPS27A STUB1 STUB1 ZNF831 ZNF831 PSMD11 PSMD11 PSMB6 PSMB6 SKP2 SKP2 PSMB10 PSMB10 PSMA7 PSMA7 PSMD9 PSMD9 PSME2 PSME2 PSME1 PSME1 PSMB5 PSMB5 PSMC2 PSMC2 PSMA1 PSMA1 PSMD10 PSMD10 LOC111166275 LOC111166275 PSMD3 PSMD3 PSMB3 PSMB3 PSMB1 PSMB1 HIVEP2 HIVEP2 LOC111166421 LOC111166421 PSMD13 PSMD13 PSMB4 PSMB4 NKX3-2 NKX3-2 PSMD4 PSMD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
PPARGC1APeroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (803 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
PSMB2Proteasome subunit beta. (201 aa)
HIVEP3Transcription factor HIVEP3. (2396 aa)
CUL1Cullin-1; Belongs to the cullin family. (776 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (504 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB7Proteasome subunit beta. (277 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (524 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
PSMB8Proteasome subunit beta. (276 aa)
HIVEP1Zinc finger protein 40 isoform X1. (2719 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
DLX5Homeobox protein DLX-5. (289 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1. (1173 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
DLX6Homeobox protein DLX-6. (296 aa)
SKP1S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (164 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
MSX2Homeobox protein MSX-2. (267 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (270 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
RBX1E3 ubiquitin-protein ligase RBX1. (108 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (303 aa)
ZNF831LOW QUALITY PROTEIN: zinc finger protein 831. (1628 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
PSMB6Proteasome subunit beta. (239 aa)
SKP2S-phase kinase-associated protein 2 isoform X1. (436 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
PSME1Proteasome activator complex subunit 1. (249 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
LOC111166275Proteasome activator complex subunit 3-like. (165 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMB1Proteasome subunit beta. (241 aa)
HIVEP2Transcription factor HIVEP2. (2440 aa)
LOC111166421Proteasome activator complex subunit 3. (254 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
NKX3-2Homeobox protein Nkx-3.2. (327 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (26%) [HD]