STRINGSTRING
MEPE MEPE SPZ1 SPZ1 EVA1C EVA1C SERPIND1 SERPIND1 APLP2 APLP2 LOC111163515 LOC111163515 PDIA6 PDIA6 PRKCSH PRKCSH LOC111166100 LOC111166100 QSOX1 QSOX1 PENK PENK FUCA2 FUCA2 TGOLN2 TGOLN2 GPC3 GPC3 ANO8 ANO8 GOLM1 GOLM1 APOA1 APOA1 APOA2 APOA2 C3 C3 F5 F5 NUCB2 NUCB2 TIMP1 TIMP1 CHGB CHGB CHRDL1 CHRDL1 FSTL1 FSTL1 PEAR1 PEAR1 IGFBP4 IGFBP4 IGFBP7 IGFBP7 APOA5 APOA5 MFGE8 MFGE8 EVA1A EVA1A PNPLA2 PNPLA2 SERPINC1 SERPINC1 LOC111170700 LOC111170700 FAM20C FAM20C FSTL3 FSTL3 BMP15 BMP15 IGFBP5 IGFBP5 FRZB FRZB MELTF MELTF SPP2 SPP2 TMEM132E TMEM132E BMP4 BMP4 KTN1 KTN1 MAPK1IP1L MAPK1IP1L FN1 FN1 KNG1 KNG1 SHISA5 SHISA5 SCG2 SCG2 MATN3 MATN3 AHSG AHSG SERPINA1 SERPINA1 APOB APOB PCSK9 PCSK9 APOLD1 APOLD1 DNAJC3 DNAJC3 QSOX2 QSOX2 FGF23 FGF23 LAMB2 LAMB2 MIA3 MIA3 APP APP SCG3 SCG3 MEGF11 MEGF11 LTBP1 LTBP1 SERPINA10 SERPINA10 GAS6 GAS6 CALU CALU ADAM10 ADAM10 ITIH2 ITIH2 CP CP CYR61 CYR61 TNC TNC TF TF SDC2 SDC2 APOE APOE SPARCL1 SPARCL1 SPP1 SPP1 WFS1 WFS1 LOC111179199 LOC111179199 DMP1 DMP1 MBTPS1 MBTPS1 RCN1 RCN1 CSF1 CSF1 HRC HRC NUCB1 NUCB1 RCN3 RCN3 APLP1 APLP1 CDH2 CDH2 FBN1 FBN1 VGF VGF MEGF10 MEGF10 MEN1 MEN1 NOTUM NOTUM P4HB P4HB FAM20A FAM20A PRSS35 PRSS35 PRSS23 PRSS23 CST3 CST3 GNPTG GNPTG PROC PROC LAMB1 LAMB1 IGFBP1 IGFBP1 IGFBP3 IGFBP3 TMEM132A TMEM132A BPIFB2 BPIFB2 LGALS1 LGALS1 SFRP4 SFRP4 VCAN VCAN LAMC1 LAMC1 CHRDL2 CHRDL2 RRBP1 RRBP1 TMEM132B TMEM132B STC2 STC2 MGAT4A MGAT4A TMEM132D TMEM132D LOC111187813 LOC111187813 AMBN AMBN AMTN AMTN FGA FGA FGG FGG LOC111187870 LOC111187870 CKAP4 CKAP4 EDIL3 EDIL3 TMEM132C TMEM132C MXRA8 MXRA8 VWA1 VWA1 AFP AFP ALB ALB APOL3 APOL3 HSP90B1 HSP90B1 IL6 IL6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEPEMatrix extracellular phosphoglycoprotein isoform X2. (555 aa)
SPZ1Spermatogenic leucine zipper protein 1. (383 aa)
EVA1CProtein eva-1 homolog C isoform X1. (458 aa)
SERPIND1Heparin cofactor 2 isoform X2; Belongs to the serpin family. (496 aa)
APLP2Amyloid-like protein 2 isoform X1. (762 aa)
LOC111163515Uncharacterized protein LOC111163515. (1806 aa)
PDIA6Protein disulfide-isomerase A6; Belongs to the protein disulfide isomerase family. (440 aa)
PRKCSHGlucosidase 2 subunit beta isoform X1. (535 aa)
LOC111166100Complement C3-like isoform X1. (1706 aa)
QSOX1Sulfhydryl oxidase. (556 aa)
PENKproenkephalin-A. (263 aa)
FUCA2Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (525 aa)
TGOLN2trans-Golgi network integral membrane protein 2 isoform X1. (320 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
ANO8Anoctamin. (1246 aa)
GOLM1Golgi membrane protein 1 isoform X2. (405 aa)
APOA1Apolipoprotein A-I. (265 aa)
APOA2Apolipoprotein A-II. (103 aa)
C3Complement C3 isoform X1. (1695 aa)
F5Coagulation factor V isoform X1; Belongs to the multicopper oxidase family. (2169 aa)
NUCB2Nucleobindin-2. (420 aa)
TIMP1Metalloproteinase inhibitor 1. (257 aa)
CHGBSecretogranin-1. (656 aa)
CHRDL1Chordin-like protein 1 isoform X1. (527 aa)
FSTL1Follistatin-related protein 1. (307 aa)
PEAR1Platelet endothelial aggregation receptor 1 isoform X1. (1041 aa)
IGFBP4Insulin-like growth factor-binding protein 4. (258 aa)
IGFBP7Insulin-like growth factor-binding protein 7. (282 aa)
APOA5Apolipoprotein A-V isoform X1. (390 aa)
MFGE8Lactadherin. (431 aa)
EVA1AProtein eva-1 homolog A. (139 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2 isoform X1. (489 aa)
SERPINC1antithrombin-III isoform X1; Belongs to the serpin family. (501 aa)
LOC111170700Complement C4-like isoform X1. (1740 aa)
FAM20CExtracellular serine/threonine protein kinase FAM20C. (585 aa)
FSTL3Follistatin-related protein 3. (262 aa)
BMP15Bone morphogenetic protein 15. (394 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (271 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (739 aa)
SPP2Secreted phosphoprotein 24 isoform X1. (190 aa)
TMEM132ETransmembrane protein 132E isoform X2. (1073 aa)
BMP4Bone morphogenetic protein 4 isoform X2. (408 aa)
KTN1Kinectin isoform X1. (1357 aa)
MAPK1IP1LMAPK-interacting and spindle-stabilizing protein-like. (245 aa)
FN1Fibronectin isoform X5. (2478 aa)
KNG1Kininogen-1 isoform X1. (627 aa)
SHISA5Protein shisa-5 isoform X1. (239 aa)
SCG2Secretogranin-2. (615 aa)
MATN3Matrilin-3. (482 aa)
AHSGalpha-2-HS-glycoprotein. (360 aa)
SERPINA1Alpha-1-antitrypsin; Belongs to the serpin family. (421 aa)
APOBApolipoprotein B-100. (4566 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9 isoform X1. (692 aa)
APOLD1Apolipoprotein L domain-containing protein 1. (248 aa)
DNAJC3dnaJ homolog subfamily C member 3. (504 aa)
QSOX2Sulfhydryl oxidase. (698 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (315 aa)
LAMB2Laminin subunit beta-2 isoform X1. (1812 aa)
MIA3Transport and Golgi organization protein 1 homolog isoform X3. (1952 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
SCG3Secretogranin-3 isoform X1. (471 aa)
MEGF11Multiple epidermal growth factor-like domains protein 11 isoform X1. (1140 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1711 aa)
SERPINA10Protein Z-dependent protease inhibitor; Belongs to the serpin family. (446 aa)
GAS6Growth arrest-specific protein 6. (671 aa)
CALUCalumenin isoform X2. (323 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (748 aa)
ITIH2Inter-alpha-trypsin inhibitor heavy chain H2 isoform X1. (946 aa)
CPCeruloplasmin isoform X1; Belongs to the multicopper oxidase family. (1061 aa)
CYR61Protein CYR61. (382 aa)
TNCTenascin isoform X1. (2201 aa)
TFSerotransferrin; Belongs to the transferrin family. (702 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
APOEApolipoprotein E. (316 aa)
SPARCL1SPARC-like protein 1. (659 aa)
SPP1Osteopontin. (362 aa)
WFS1Wolframin. (889 aa)
LOC111179199Serotransferrin-like; Belongs to the transferrin family. (706 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (517 aa)
MBTPS1Membrane-bound transcription factor site-1 protease isoform X1. (1054 aa)
RCN1Reticulocalbin-1 isoform X1. (384 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (554 aa)
HRCSarcoplasmic reticulum histidine-rich calcium-binding protein. (580 aa)
NUCB1Nucleobindin-1. (457 aa)
RCN3Reticulocalbin-3 isoform X1. (360 aa)
APLP1Amyloid-like protein 1 isoform X1. (647 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
FBN1Fibrillin-1 isoform X1. (2871 aa)
VGFNeurosecretory protein VGF. (616 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1139 aa)
MEN1Menin isoform X1. (616 aa)
NOTUMPalmitoleoyl-protein carboxylesterase NOTUM. (499 aa)
P4HBProtein disulfide-isomerase. (510 aa)
FAM20APseudokinase FAM20A isoform X1. (887 aa)
PRSS35Inactive serine protease 35. (413 aa)
PRSS23Serine protease 23. (375 aa)
CST3cystatin-C; Belongs to the cystatin family. (147 aa)
GNPTGN-acetylglucosamine-1-phosphotransferase subunit gamma. (306 aa)
PROCVitamin K-dependent protein C. (480 aa)
LAMB1Laminin subunit beta-1. (1786 aa)
IGFBP1Insulin-like growth factor-binding protein 1. (263 aa)
IGFBP3Insulin-like growth factor-binding protein 3. (293 aa)
TMEM132ATransmembrane protein 132A isoform X1. (1023 aa)
BPIFB2LOW QUALITY PROTEIN: BPI fold-containing family B member 2. (406 aa)
LGALS1Galectin. (135 aa)
SFRP4Secreted frizzled-related protein 4. (346 aa)
VCANVersican core protein isoform X1. (3392 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
CHRDL2Chordin-like protein 2 isoform X2. (452 aa)
RRBP1LOW QUALITY PROTEIN: ribosome-binding protein 1. (1369 aa)
TMEM132BTransmembrane protein 132B isoform X1. (1084 aa)
STC2Stanniocalcin-2. (302 aa)
MGAT4AAlpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform X1. (535 aa)
TMEM132DTransmembrane protein 132D. (1094 aa)
LOC111187813Apolipoprotein L2-like. (268 aa)
AMBNAmeloblastin. (417 aa)
AMTNAmelotin. (189 aa)
FGAFibrinogen alpha chain. (852 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
LOC111187870Apolipoprotein L6-like. (341 aa)
CKAP4Cytoskeleton-associated protein 4. (596 aa)
EDIL3EGF-like repeat and discoidin I-like domain-containing protein 3. (453 aa)
TMEM132CTransmembrane protein 132C. (1094 aa)
MXRA8Matrix remodeling-associated protein 8 isoform X1. (495 aa)
VWA1Von Willebrand factor A domain-containing protein 1. (413 aa)
AFPAlpha-fetoprotein. (585 aa)
ALBSerum albumin. (607 aa)
APOL3Apolipoprotein L3. (186 aa)
HSP90B1Endoplasmin. (805 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.