STRINGSTRING
LOC111170129 LOC111170129 ABCA1 ABCA1 GNB1 GNB1 DHRS3 DHRS3 EPGN EPGN XPO1 XPO1 TNRC6B TNRC6B IGF1R IGF1R PRKCZ PRKCZ PIK3R1 PIK3R1 ZNF217 ZNF217 ALDH1A3 ALDH1A3 EP300 EP300 POLR2F POLR2F PDPK1 PDPK1 GPS2 GPS2 CPT1B CPT1B RDH10 RDH10 CREBBP CREBBP CHD1 CHD1 POLR2A POLR2A DHRS13 DHRS13 GNG3 GNG3 NCOA2 NCOA2 POLR2D POLR2D GNG13 GNG13 SRC SRC HDAC3 HDAC3 DDX5 DDX5 NR1H3 NR1H3 LOC111184525 LOC111184525 DLD DLD CXXC5 CXXC5 POLR2G POLR2G KAT5 KAT5 CPT1A CPT1A SPHK1 SPHK1 USF2 USF2 GNGT1 GNGT1 RDH13 RDH13 LOC111182289 LOC111182289 HSPB1 HSPB1 POLR2J POLR2J PPP5C PPP5C GNG8 GNG8 GNB2 GNB2 CPT1C CPT1C MAPK3 MAPK3 EBAG9 EBAG9 ARL4A ARL4A STRN4 STRN4 GNAI3 GNAI3 NRAS NRAS PDHX PDHX EEPD1 EEPD1 PDK4 PDK4 POLR2I POLR2I FOSB FOSB PPID PPID GNG11 GNG11 POLR2K POLR2K RXRB RXRB NR1H2 NR1H2 GNG12 GNG12 PRMT1 PRMT1 PDHA2 PDHA2 GNG5 GNG5 HSP90AB1 HSP90AB1 GATA3 GATA3 CSDE1 CSDE1 ZDHHC7 ZDHHC7 GTF2A2 GTF2A2 CAV2 CAV2 CAV1 CAV1 LOC111179105 LOC111179105 ADH1C ADH1C CDKN1B CDKN1B WDR64 WDR64 LOC111177332 LOC111177332 FKBP4 FKBP4 PPARD PPARD KANK4 KANK4 GTF2A1 GTF2A1 CALM1 CALM1 ALDH1A2 ALDH1A2 GNB5 GNB5 FKBP5 FKBP5 LOC111176690 LOC111176690 TLE3 TLE3 CRABP1 CRABP1 DHRS12 DHRS12 RXRA RXRA NRIP1 NRIP1 CDK9 CDK9 ZDHHC21 ZDHHC21 KANK1 KANK1 ALDH1A1 ALDH1A1 FOS FOS GNB3 GNB3 ABCA2 ABCA2 KRAS KRAS NOS3 NOS3 LOC111176794 LOC111176794 LOC111176743 LOC111176743 PRMT8 PRMT8 LOC111174638 LOC111174638 GTF2F2 GTF2F2 YY1 YY1 POLR2H POLR2H PIK3R3 PIK3R3 GNG2 GNG2 PDHB PDHB HSP90AA1 HSP90AA1 ZC3H12A ZC3H12A SRBD1 SRBD1 GTF2A1L GTF2A1L HDAC1 HDAC1 LOC111172488 LOC111172488 NCOA1 NCOA1 STRN STRN FOXA1 FOXA1 CCNT1 CCNT1 SP1 SP1 GNAI2 GNAI2 PTGES3 PTGES3 GNB4 GNB4 DHRS9 DHRS9 ZFP42 ZFP42 LOC111172487 LOC111172487 RDH5 RDH5 TBL1XR1 TBL1XR1 PIK3CA PIK3CA RARG RARG CITED1 CITED1 PDK1 PDK1 ESR2 ESR2 RDH11 RDH11 LOC111171155 LOC111171155 GNG7 GNG7 LOC111169748 LOC111169748 LOC111169736 LOC111169736 ERBB4 ERBB4 UHMK1 UHMK1 LOC111169315 LOC111169315 RXRG RXRG LOC111171154 LOC111171154 LOC111171120 LOC111171120 ARL4C ARL4C LOC111168544 LOC111168544 LOC111168536 LOC111168536 LOC111168448 LOC111168448 LOC111168443 LOC111168443 NR5A2 NR5A2 ERAS ERAS TBP TBP POLR2L POLR2L POLR2B POLR2B POLR2E POLR2E PDHA1 PDHA1 HRAS HRAS LOC111168531 LOC111168531 LOC111168527 LOC111168527 LOC111168460 LOC111168460 LOC111168446 LOC111168446 LOC111170125 LOC111170125 NCOA3 NCOA3 LOC111169749 LOC111169749 ZC3H12B ZC3H12B PLIN1 PLIN1 USF1 USF1 PDK3 PDK3 LOC111168530 LOC111168530 LOC111168526 LOC111168526 LOC111168521 LOC111168521 LOC111168516 LOC111168516 LOC111169056 LOC111169056 JUND JUND POU2F1 POU2F1 LOC111169091 LOC111169091 PDK2 PDK2 TBL1X TBL1X LOC111168529 LOC111168529 LOC111168525 LOC111168525 LOC111168515 LOC111168515 LOC111168445 LOC111168445 LOC111168549 LOC111168549 LOC111168528 LOC111168528 LOC111168524 LOC111168524 LOC111168449 LOC111168449 PGR PGR GTF2F1 GTF2F1 LOC111167902 LOC111167902 ZC3H12C ZC3H12C TGFA TGFA NCOR1 NCOR1 S1PR3 S1PR3 LOC111166305 LOC111166305 ESR1 ESR1 KANK3 KANK3 DLAT DLAT ZC3H12D ZC3H12D PTK2 PTK2 CARM1 CARM1 CRABP2 CRABP2 LOC111165821 LOC111165821 SHC1 SHC1 MED1 MED1 PIK3R2 PIK3R2 GNG14 GNG14 RARA RARA STRN3 STRN3 LOC111164139 LOC111164139 KDM4B KDM4B KANK2 KANK2 TBPL1 TBPL1 ELK1 ELK1 RARB RARB MYB MYB ALDH8A1 ALDH8A1 LOC111165935 LOC111165935 GNAI1 GNAI1 POLR2C POLR2C FABP5 FABP5 TRPS1 TRPS1 LOC111164472 LOC111164472 FOXO3 FOXO3 KDM1A KDM1A KAT2B KAT2B RUNX1 RUNX1 GNGT2 GNGT2 TFF3 TFF3 GNG4 GNG4 MAPK1 MAPK1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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LOC111170129Aldo-keto reductase family 1 member C3 homolog. (324 aa)
ABCA1ATP-binding cassette sub-family A member 1 isoform X1. (2273 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
DHRS3Short-chain dehydrogenase/reductase 3 isoform X1. (360 aa)
EPGNEpigen. (153 aa)
XPO1Exportin-1 isoform X1. (1071 aa)
TNRC6BTrinucleotide repeat-containing gene 6B protein isoform X1. (1867 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
ZNF217Zinc finger protein 217. (1044 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
EP300Histone acetyltransferase p300. (2420 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1. (127 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
GPS2G protein pathway suppressor 2. (327 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (780 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
CREBBPCREB-binding protein isoform X1. (2442 aa)
CHD1chromodomain-helicase-DNA-binding protein 1 isoform X1. (1798 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
DHRS13Dehydrogenase/reductase SDR family member 13. (374 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
SRCTyrosine-protein kinase. (562 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
DDX5Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
LOC111184525Histone H2A; Belongs to the histone H2A family. (128 aa)
DLDDihydrolipoyl dehydrogenase. (509 aa)
CXXC5CXXC-type zinc finger protein 5. (321 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7 isoform X1. (172 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
CPT1ACarnitine O-palmitoyltransferase 1, liver isoform; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
SPHK1Sphingosine kinase 1 isoform X2. (484 aa)
USF2Upstream stimulatory factor 2. (347 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
LOC111182289LOW QUALITY PROTEIN: uroplakin-3b-like protein 1. (253 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (117 aa)
PPP5CSerine/threonine-protein phosphatase. (499 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
CPT1CCarnitine O-palmitoyltransferase 1, brain isoform isoform X1. (836 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells isoform X2. (336 aa)
ARL4AADP-ribosylation factor-like protein 4A. (200 aa)
STRN4Striatin-4. (760 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
NRASGTPase NRas. (189 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (514 aa)
EEPD1Endonuclease/exonuclease/phosphatase family domain-containing protein 1. (569 aa)
PDK4Protein-serine/threonine kinase. (407 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (132 aa)
FOSBProtein fosB isoform X1. (341 aa)
PPIDPeptidyl-prolyl cis-trans isomerase D isoform X1. (383 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
RXRBRetinoic acid receptor RXR-beta isoform X1. (538 aa)
NR1H2Oxysterols receptor LXR-beta isoform X1. (450 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
PDHA2Pyruvate dehydrogenase E1 component alpha subunit. (387 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
HSP90AB1Heat shock protein HSP 90-beta. (724 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (798 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (308 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
LOC111179105Histone H2A; Belongs to the histone H2A family. (128 aa)
ADH1CAlcohol dehydrogenase 1C isoform X1. (375 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
WDR64WD repeat-containing protein 64. (1081 aa)
LOC111177332Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
FKBP4Peptidylprolyl isomerase. (458 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
KANK4KN motif and ankyrin repeat domain-containing protein 4. (1003 aa)
GTF2A1Transcription initiation factor IIA subunit 1. (375 aa)
CALM1Calmodulin-1; Belongs to the calmodulin family. (149 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (414 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
LOC111176690Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
TLE3Transducin-like enhancer protein 3 isoform X7. (776 aa)
CRABP1Cellular retinoic acid-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
DHRS12Dehydrogenase/reductase SDR family member 12 isoform X2. (328 aa)
RXRARetinoic acid receptor RXR-alpha isoform X1. (495 aa)
NRIP1Nuclear receptor-interacting protein 1. (1156 aa)
CDK9Cyclin-dependent kinase 9 isoform X2; Belongs to the protein kinase superfamily. (488 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X3. (1351 aa)
ALDH1A1Retinal dehydrogenase 1; Belongs to the aldehyde dehydrogenase family. (501 aa)
FOSProto-oncogene c-Fos. (380 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X2. (299 aa)
ABCA2ATP-binding cassette sub-family A member 2 isoform X1. (2438 aa)
KRASGTPase KRas. (188 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
LOC111176794Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC111176743Histone H2B; Belongs to the histone H2B family. (122 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
LOC111174638Histone-arginine methyltransferase CARM1-like isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (463 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
YY1Transcriptional repressor protein YY1. (412 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (733 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
SRBD1S1 RNA-binding domain-containing protein 1 isoform X1. (1022 aa)
GTF2A1LTFIIA-alpha and beta-like factor. (533 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (393 aa)
LOC111172488Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (523 aa)
NCOA1Nuclear receptor coactivator. (1441 aa)
STRNStriatin isoform X1. (809 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
CCNT1cyclin-T1; Belongs to the cyclin family. (727 aa)
SP1Transcription factor Sp1. (786 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
PTGES3Prostaglandin E synthase 3 isoform X1. (177 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4 isoform X1. (340 aa)
DHRS9Dehydrogenase/reductase SDR family member 9 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (396 aa)
ZFP42Zinc finger protein 42 homolog. (299 aa)
LOC111172487Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (497 aa)
RDH511-cis retinol dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1. (514 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (359 aa)
PDK1Protein-serine/threonine kinase. (438 aa)
ESR2Estrogen receptor beta. (558 aa)
RDH11Retinol dehydrogenase 11 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
LOC111171155Histone H2B; Belongs to the histone H2B family. (126 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC111169748Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC111169736Histone H2B; Belongs to the histone H2B family. (197 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
UHMK1Serine/threonine-protein kinase Kist. (419 aa)
LOC111169315Histone H2B; Belongs to the histone H2B family. (126 aa)
RXRGRetinoic acid receptor RXR-gamma isoform X1. (463 aa)
LOC111171154Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111171120Late histone H2B.L4-like; Belongs to the histone H2B family. (135 aa)
ARL4CADP-ribosylation factor-like protein 4C; Belongs to the small GTPase superfamily. Arf family. (192 aa)
LOC111168544Histone H2B type 1-L-like; Belongs to the histone H2B family. (143 aa)
LOC111168536Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC111168448Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168443Histone H2A; Belongs to the histone H2A family. (130 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2 isoform X1. (501 aa)
ERASGTPase ERas. (233 aa)
TBPTATA-box-binding protein. (319 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
HRASGTPase HRas isoform X1. (189 aa)
LOC111168531Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (112 aa)
LOC111168527Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168460Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC111168446Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111170125Myosin light chain 1, skeletal muscle isoform-like isoform X1; Belongs to the calmodulin family. (304 aa)
NCOA3Nuclear receptor coactivator. (1406 aa)
LOC111169749Histone H2B; Belongs to the histone H2B family. (126 aa)
ZC3H12BProbable ribonuclease ZC3H12B. (836 aa)
PLIN1Perilipin; Belongs to the perilipin family. (517 aa)
USF1Upstream stimulatory factor 1 isoform X1. (310 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
LOC111168530Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168526Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168521Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC111168516Histone H3; Belongs to the histone H3 family. (136 aa)
LOC111169056LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase D-like. (370 aa)
JUNDTranscription factor jun-D. (345 aa)
POU2F1POU domain protein. (756 aa)
LOC111169091Retinol dehydrogenase 12-like isoform X1. (355 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
TBL1XF-box-like/WD repeat-containing protein TBL1X isoform X1. (544 aa)
LOC111168529Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168525Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168515Histone H3; Belongs to the histone H3 family. (136 aa)
LOC111168445Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168549Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC111168528Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168524Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC111168449Histone H2B; Belongs to the histone H2B family. (126 aa)
PGRProgesterone receptor. (936 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (518 aa)
LOC111167902Cytochrome P450 26B1 isoform X1; Belongs to the cytochrome P450 family. (512 aa)
ZC3H12CProbable ribonuclease ZC3H12C isoform X1. (886 aa)
TGFAProtransforming growth factor alpha isoform X1. (176 aa)
NCOR1Nuclear receptor corepressor 1 isoform X1. (2454 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (378 aa)
LOC111166305alanyl-tRNA editing protein Aarsd1 isoform X1. (588 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
KANK3KN motif and ankyrin repeat domain-containing protein 3 isoform X1. (811 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
ZC3H12DProbable ribonuclease ZC3H12D. (495 aa)
PTK2Focal adhesion kinase 1 isoform X22; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1116 aa)
CARM1Histone-arginine methyltransferase CARM1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (664 aa)
CRABP2Cellular retinoic acid-binding protein 2 isoform X1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (144 aa)
LOC111165821Epidermal retinol dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
GNG14LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (101 aa)
RARARetinoic acid receptor alpha isoform X5. (584 aa)
STRN3Striatin-3 isoform X5. (796 aa)
LOC111164139Dehydrogenase/reductase SDR family member 4 isoform X1. (279 aa)
KDM4BLysine-specific demethylase 4B isoform X1. (1121 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2 isoform X1. (857 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
ELK1LOW QUALITY PROTEIN: ETS domain-containing protein Elk-1. (442 aa)
RARBRetinoic acid receptor beta isoform X1. (448 aa)
MYBTranscriptional activator Myb isoform X3. (761 aa)
ALDH8A1Aldehyde dehydrogenase family 8 member A1; Belongs to the aldehyde dehydrogenase family. (491 aa)
LOC111165935Ras-like protein isoform X1. (285 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (275 aa)
FABP5Fatty acid-binding protein, epidermal isoform X1. (140 aa)
TRPS1Zinc finger transcription factor Trps1 isoform X2. (1293 aa)
LOC111164472Retinol dehydrogenase 14 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
FOXO3Forkhead box protein O3. (672 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (828 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
TFF3Trefoil factor 3. (80 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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