STRINGSTRING
NCK2 NCK2 LOC111187154 LOC111187154 GIT2 GIT2 DEPDC1B DEPDC1B CDC42 CDC42 CLTC CLTC RHOU RHOU USP9X USP9X PEAK3 PEAK3 ARHGEF6 ARHGEF6 PIK3R2 PIK3R2 ARHGAP30 ARHGAP30 PAK3 PAK3 ARHGAP31 ARHGAP31 IQGAP1 IQGAP1 PAK2 PAK2 STAM2 STAM2 MACF1 MACF1 ARHGEF7 ARHGEF7 WDR6 WDR6 PEAK1 PEAK1 ITSN2 ITSN2 DST DST STAM STAM NCK1 NCK1 WWP2 WWP2 SPTAN1 SPTAN1 TXNL1 TXNL1 VANGL1 VANGL1 PARD6A PARD6A PAK4 PAK4 HGS HGS GRB2 GRB2 MYO6 MYO6 DLG5 DLG5 PAK1 PAK1 PTK2B PTK2B GIT1 GIT1 PIK3R1 PIK3R1 EPHA2 EPHA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCK2Cytoplasmic protein. (376 aa)
LOC111187154Ephrin type-A receptor 2-like. (171 aa)
GIT2ARF GTPase-activating protein GIT2 isoform X1. (759 aa)
DEPDC1BDEP domain-containing protein 1B isoform X1. (502 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
RHOURho-related GTP-binding protein RhoU. (255 aa)
USP9XProbable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1; Belongs to the peptidase C19 family. (2559 aa)
PEAK3Uncharacterized protein. (436 aa)
ARHGEF6Rho guanine nucleotide exchange factor 6 isoform X1. (780 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
ARHGAP30Rho GTPase-activating protein 30 isoform X1. (1125 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
ARHGAP31Rho GTPase-activating protein 31. (1452 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1657 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
STAM2Signal transducing adapter molecule 2 isoform X1. (604 aa)
MACF1Microtubule-actin cross-linking factor 1 isoform X1. (7690 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7 isoform X1. (862 aa)
WDR6WD repeat-containing protein 6. (1120 aa)
PEAK1Pseudopodium-enriched atypical kinase 1. (1745 aa)
ITSN2Intersectin-2 isoform X1. (1667 aa)
DSTDystonin isoform X1. (7806 aa)
STAMSignal transducing adapter molecule 1. (526 aa)
NCK1Cytoplasmic protein. (377 aa)
WWP2E3 ubiquitin-protein ligase. (868 aa)
SPTAN1Spectrin alpha chain, non-erythrocytic 1 isoform X1. (2477 aa)
TXNL1Thioredoxin-like protein 1 isoform X1. (289 aa)
VANGL1Vang-like protein. (529 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
PAK4Non-specific serine/threonine protein kinase. (594 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
MYO6Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa)
DLG5Disks large homolog 5 isoform X1; Belongs to the MAGUK family. (1980 aa)
PAK1Non-specific serine/threonine protein kinase. (543 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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