10 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SHC1	SHC-transforming protein 1 isoform X1. (609 aa)
	JAK3	Tyrosine-protein kinase. (1104 aa)
	STAT5A	Signal transducer and activator of transcription. (818 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	IL2RG	Cytokine receptor common subunit gamma isoform X1. (381 aa)
	LCK	Tyrosine-protein kinase. (509 aa)
	JAK1	Tyrosine-protein kinase. (1153 aa)
	IL2RB	Interleukin-2 receptor subunit beta isoform X1. (595 aa)
	PTK2B	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL2	IL2RB	Q9XT84	A0A2Y9Q4J8	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Interleukin-2 receptor subunit beta isoform X1.	0.991
IL2	IL2RG	Q9XT84	A0A2Y9MHV1	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Cytokine receptor common subunit gamma isoform X1.	0.994
IL2	JAK1	Q9XT84	A0A2Y9P436	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Tyrosine-protein kinase.	0.966
IL2	JAK3	Q9XT84	A0A2Y9M4G7	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Tyrosine-protein kinase.	0.971
IL2	LCK	Q9XT84	A0A2Y9NNB7	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Tyrosine-protein kinase.	0.532
IL2	STAT5A	Q9XT84	A0A2Y9LW47	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Signal transducer and activator of transcription.	0.740
IL2	SYK	Q9XT84	A0A2Y9MGM5	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	Tyrosine-protein kinase.	0.403
IL2RB	IL2	A0A2Y9Q4J8	Q9XT84	Interleukin-2 receptor subunit beta isoform X1.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	0.991
IL2RB	IL2RG	A0A2Y9Q4J8	A0A2Y9MHV1	Interleukin-2 receptor subunit beta isoform X1.	Cytokine receptor common subunit gamma isoform X1.	0.997
IL2RB	JAK1	A0A2Y9Q4J8	A0A2Y9P436	Interleukin-2 receptor subunit beta isoform X1.	Tyrosine-protein kinase.	0.997
IL2RB	JAK3	A0A2Y9Q4J8	A0A2Y9M4G7	Interleukin-2 receptor subunit beta isoform X1.	Tyrosine-protein kinase.	0.989
IL2RB	LCK	A0A2Y9Q4J8	A0A2Y9NNB7	Interleukin-2 receptor subunit beta isoform X1.	Tyrosine-protein kinase.	0.483
IL2RB	SHC1	A0A2Y9Q4J8	A0A2Y9LZK9	Interleukin-2 receptor subunit beta isoform X1.	SHC-transforming protein 1 isoform X1.	0.524
IL2RB	STAT5A	A0A2Y9Q4J8	A0A2Y9LW47	Interleukin-2 receptor subunit beta isoform X1.	Signal transducer and activator of transcription.	0.945
IL2RB	SYK	A0A2Y9Q4J8	A0A2Y9MGM5	Interleukin-2 receptor subunit beta isoform X1.	Tyrosine-protein kinase.	0.452
IL2RG	IL2	A0A2Y9MHV1	Q9XT84	Cytokine receptor common subunit gamma isoform X1.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family.	0.994
IL2RG	IL2RB	A0A2Y9MHV1	A0A2Y9Q4J8	Cytokine receptor common subunit gamma isoform X1.	Interleukin-2 receptor subunit beta isoform X1.	0.997
IL2RG	JAK1	A0A2Y9MHV1	A0A2Y9P436	Cytokine receptor common subunit gamma isoform X1.	Tyrosine-protein kinase.	0.988
IL2RG	JAK3	A0A2Y9MHV1	A0A2Y9M4G7	Cytokine receptor common subunit gamma isoform X1.	Tyrosine-protein kinase.	0.997
IL2RG	STAT5A	A0A2Y9MHV1	A0A2Y9LW47	Cytokine receptor common subunit gamma isoform X1.	Signal transducer and activator of transcription.	0.936