STRINGSTRING
IL2 IL2 IL2RB IL2RB JAK1 JAK1 LCK LCK STAT5A STAT5A SHC1 SHC1 JAK3 JAK3 SYK SYK IL2RG IL2RG PTK2B PTK2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
IL2RBInterleukin-2 receptor subunit beta isoform X1. (595 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
LCKTyrosine-protein kinase. (509 aa)
STAT5ASignal transducer and activator of transcription. (818 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
SYKTyrosine-protein kinase. (626 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1015 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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