12 items (Delphinapterus leucas) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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protein homology

Your Input:
	PIK3CG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
	LOC111165942	Erythropoietin receptor; Receptor for erythropoietin. (509 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	JAK2	Tyrosine-protein kinase. (1132 aa)
	IRS2	Insulin receptor substrate 2. (1347 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	EPO	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	PIK3R5	Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa)
	GAB1	GRB2-associated-binding protein 1 isoform X1. (757 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPO	IRS2	A0A2Y9PM33	A0A2Y9NC55	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Insulin receptor substrate 2.	0.437
EPO	JAK2	A0A2Y9PM33	A0A2Y9N3T7	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Tyrosine-protein kinase.	0.931
EPO	LOC111165942	A0A2Y9PM33	A0A2Y9LSV2	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Erythropoietin receptor; Receptor for erythropoietin.	0.996
EPO	LYN	A0A2Y9PM33	A0A2Y9LZZ2	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Tyrosine-protein kinase.	0.584
EPO	PIK3CA	A0A2Y9PM33	A0A2Y9MZW2	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.501
EPO	PIK3CB	A0A2Y9PM33	A0A2Y9NZC3	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.501
EPO	PIK3CD	A0A2Y9PM33	A0A2Y9QGK3	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.501
EPO	PIK3CG	A0A2Y9PM33	A0A2Y9LSJ4	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.501
EPO	PIK3R1	A0A2Y9PM33	A0A2Y9Q8T5	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.504
GAB1	IRS2	A0A2Y9QCZ2	A0A2Y9NC55	GRB2-associated-binding protein 1 isoform X1.	Insulin receptor substrate 2.	0.470
GAB1	JAK2	A0A2Y9QCZ2	A0A2Y9N3T7	GRB2-associated-binding protein 1 isoform X1.	Tyrosine-protein kinase.	0.546
GAB1	LOC111165942	A0A2Y9QCZ2	A0A2Y9LSV2	GRB2-associated-binding protein 1 isoform X1.	Erythropoietin receptor; Receptor for erythropoietin.	0.502
GAB1	LYN	A0A2Y9QCZ2	A0A2Y9LZZ2	GRB2-associated-binding protein 1 isoform X1.	Tyrosine-protein kinase.	0.578
GAB1	PIK3CA	A0A2Y9QCZ2	A0A2Y9MZW2	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.954
GAB1	PIK3CB	A0A2Y9QCZ2	A0A2Y9NZC3	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.954
GAB1	PIK3CD	A0A2Y9QCZ2	A0A2Y9QGK3	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.970
GAB1	PIK3CG	A0A2Y9QCZ2	A0A2Y9LSJ4	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family.	0.568
GAB1	PIK3R1	A0A2Y9QCZ2	A0A2Y9Q8T5	GRB2-associated-binding protein 1 isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.986
GAB1	PIK3R5	A0A2Y9QCZ2	A0A2Y9Q8V7	GRB2-associated-binding protein 1 isoform X1.	Phosphoinositide 3-kinase regulatory subunit 5 isoform X1.	0.507
IRS2	EPO	A0A2Y9NC55	A0A2Y9PM33	Insulin receptor substrate 2.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.437