STRINGSTRING
NTF4 NTF4 GRB2 GRB2 BDNF BDNF SOS1 SOS1 FRS2 FRS2 NTRK2 NTRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (247 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
NTRK2Tyrosine-protein kinase receptor. (822 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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