STRINGSTRING
ABCE1 ABCE1 KPNB1 KPNB1 IFNAR2 IFNAR2 IFNAR1 IFNAR1 IRF4 IRF4 SOCS1 SOCS1 PTPN1 PTPN1 IRF9 IRF9 PTPN11 PTPN11 LOC111163129 LOC111163129 IFNE IFNE LOC111187198 LOC111187198 FOXS1 FOXS1 LOC111184719 LOC111184719 IRF5 IRF5 JAK1 JAK1 ISG20 ISG20 LOC111171211 LOC111171211 STAT1 STAT1 LOC111171121 LOC111171121 SOCS3 SOCS3 EGR1 EGR1 LOC111184322 LOC111184322 IRF8 IRF8 PTPN6 PTPN6 USP18 USP18 IFNB1 IFNB1 IRF2 IRF2 LOC111171122 LOC111171122 STAT2 STAT2 KPNA1 KPNA1 IRF1 IRF1 RNASEL RNASEL LOC111163130 LOC111163130 TYK2 TYK2 IFI35 IFI35 LOC111184716 LOC111184716
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCE1ATP-binding cassette sub-family E member 1. (599 aa)
KPNB1Importin subunit beta-1. (876 aa)
IFNAR2Interferon alpha/beta receptor 2 isoform X1. (594 aa)
IFNAR1Interferon alpha/beta receptor 1 isoform X1. (561 aa)
IRF4Interferon regulatory factor 4 isoform X1. (451 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (451 aa)
IRF9LOW QUALITY PROTEIN: interferon regulatory factor 9. (479 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (623 aa)
LOC111163129Interferon omega-1-like. (250 aa)
IFNEInterferon epsilon. (193 aa)
LOC111187198Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (617 aa)
FOXS1Forkhead box protein S1. (330 aa)
LOC111184719Interferon regulatory factor 6 isoform X1. (467 aa)
IRF5Interferon regulatory factor 5 isoform X1. (517 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
ISG20Interferon-stimulated gene 20 kDa protein. (171 aa)
LOC1111712112'-5'-oligoadenylate synthase 1-like isoform X1. (137 aa)
STAT1Signal transducer and activator of transcription. (749 aa)
LOC111171121Interferon alpha-1-like. (133 aa)
SOCS3Suppressor of cytokine signaling 3. (237 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (531 aa)
LOC111184322LOW QUALITY PROTEIN: interferon regulatory factor 4-like. (561 aa)
IRF8Interferon regulatory factor 8 isoform X1. (427 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
USP18Ubl carboxyl-terminal hydrolase 18 isoform X1; Belongs to the peptidase C19 family. (321 aa)
IFNB1Interferon beta. (185 aa)
IRF2Interferon regulatory factor. (349 aa)
LOC111171122Interferon alpha-1-like isoform X1. (195 aa)
STAT2Signal transducer and activator of transcription. (911 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
IRF1Interferon regulatory factor. (322 aa)
RNASEL2-5A-dependent ribonuclease isoform X1. (665 aa)
LOC111163130Interferon alpha-1-like. (226 aa)
TYK2Tyrosine-protein kinase. (1188 aa)
IFI35Interferon-induced 35 kDa protein isoform X1. (302 aa)
LOC111184716Interferon regulatory factor 6 isoform X2. (485 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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