STRINGSTRING
PIK3CD PIK3CD PIK3R2 PIK3R2 SHC1 SHC1 JAK3 JAK3 CSF2RA CSF2RA IL2RG IL2RG IL3RA IL3RA INPPL1 INPPL1 INPP5D INPP5D PIK3CA PIK3CA JAK2 JAK2 IL5RA IL5RA SOS1 SOS1 PIK3R3 PIK3R3 PTPN6 PTPN6 PIK3CB PIK3CB IL2RA IL2RA JAK1 JAK1 CSF2 CSF2 GRB2 GRB2 IL5 IL5 CSF2RB CSF2RB GAB2 GAB2 IL2RB IL2RB IL2 IL2 PIK3R1 PIK3R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
SHC1SHC-transforming protein 1 isoform X1. (609 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1. (430 aa)
IL2RGCytokine receptor common subunit gamma isoform X1. (381 aa)
IL3RAInterleukin-3 receptor subunit alpha isoform X1. (473 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL5RAInterleukin-5 receptor subunit alpha isoform X1. (417 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1333 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
IL2RAInterleukin-2 receptor subunit alpha. (275 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
CSF2RBCytokine receptor common subunit beta. (902 aa)
GAB2GRB2-associated-binding protein 2 isoform X1. (678 aa)
IL2RBInterleukin-2 receptor subunit beta isoform X1. (595 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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