19 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRK	Adapter molecule crk isoform X1. (304 aa)
	HCK	Tyrosine-protein kinase. (506 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1 isoform X1. (1259 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	LOC111184310	Tyrosine-protein kinase. (369 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	CRKL	Crk-like protein. (303 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	CBL	E3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	CRK	A0A2Y9M339	A0A2Y9PWG4	E3 ubiquitin-protein ligase CBL isoform X1.	Adapter molecule crk isoform X1.	0.993
CBL	CRKL	A0A2Y9M339	A0A2Y9LB74	E3 ubiquitin-protein ligase CBL isoform X1.	Crk-like protein.	0.998
CBL	FYN	A0A2Y9M339	A0A2Y9LLH3	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.876
CBL	GRB2	A0A2Y9M339	A0A2Y9PJ90	E3 ubiquitin-protein ligase CBL isoform X1.	Growth factor receptor-bound protein 2.	0.997
CBL	HCK	A0A2Y9M339	A0A2Y9PT83	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.683
CBL	LOC111184310	A0A2Y9M339	A0A2Y9PNF5	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.683
CBL	LYN	A0A2Y9M339	A0A2Y9LZZ2	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.915
CBL	PIK3CA	A0A2Y9M339	A0A2Y9MZW2	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.867
CBL	PIK3CB	A0A2Y9M339	A0A2Y9NZC3	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.867
CBL	PIK3CD	A0A2Y9M339	A0A2Y9QGK3	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.841
CBL	PIK3R1	A0A2Y9M339	A0A2Y9Q8T5	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.987
CBL	PIK3R2	A0A2Y9M339	A0A2Y9LXY5	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.919
CBL	PIK3R3	A0A2Y9M339	A0A2Y9NAQ0	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.	0.895
CBL	RAPGEF1	A0A2Y9M339	A0A2Y9NJ55	E3 ubiquitin-protein ligase CBL isoform X1.	Rap guanine nucleotide exchange factor 1 isoform X1.	0.976
CBL	RPS27A	A0A2Y9M339	A0A2Y9Q1L7	E3 ubiquitin-protein ligase CBL isoform X1.	ubiquitin-40S ribosomal protein S27a.	0.841
CBL	SYK	A0A2Y9M339	A0A2Y9MGM5	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.955
CBL	VAV1	A0A2Y9M339	A0A2Y9LSY4	E3 ubiquitin-protein ligase CBL isoform X1.	Proto-oncogene vav isoform X1.	0.972
CBL	YES1	A0A2Y9M339	A0A2Y9PB67	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.760
CRK	CBL	A0A2Y9PWG4	A0A2Y9M339	Adapter molecule crk isoform X1.	E3 ubiquitin-protein ligase CBL isoform X1.	0.993
CRK	CRKL	A0A2Y9PWG4	A0A2Y9LB74	Adapter molecule crk isoform X1.	Crk-like protein.	0.961