STRINGSTRING
PIK3R1 PIK3R1 CRKL CRKL FYN FYN VAV1 VAV1 PIK3R2 PIK3R2 LYN LYN CBL CBL SYK SYK PIK3CA PIK3CA PIK3R3 PIK3R3 RAPGEF1 RAPGEF1 PIK3CB PIK3CB YES1 YES1 GRB2 GRB2 LOC111184310 LOC111184310 HCK HCK CRK CRK RPS27A RPS27A PIK3CD PIK3CD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CRKLCrk-like protein. (303 aa)
FYNTyrosine-protein kinase. (537 aa)
VAV1Proto-oncogene vav isoform X1. (845 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
LYNTyrosine-protein kinase. (518 aa)
CBLE3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
SYKTyrosine-protein kinase. (626 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1259 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
YES1Tyrosine-protein kinase. (541 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
LOC111184310Tyrosine-protein kinase. (369 aa)
HCKTyrosine-protein kinase. (506 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.