30 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRAS	GTPase KRas. (188 aa)
	CSK	Tyrosine-protein kinase. (528 aa)
	CDKN1B	Cyclin-dependent kinase inhibitor 1B. (198 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (798 aa)
	FLT3LG	Fms-related tyrosine kinase 3 ligand isoform X1. (328 aa)
	NRAS	GTPase NRas. (189 aa)
	SOCS6	Suppressor of cytokine signaling 6. (535 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	GRB10	Growth factor receptor-bound protein 10 isoform X1. (588 aa)
	SLA2	Src-like-adapter 2 isoform X1. (276 aa)
	LOC111186271	GRB2-related adapter protein 2-like isoform X1. (105 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	LOC111187339	LOW QUALITY PROTEIN: growth factor receptor-bound protein 10-like. (665 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	LOC111186270	GRB2-related adapter protein 2 isoform X1. (337 aa)
	SH2B3	SH2B adapter protein 3 isoform X1. (618 aa)
	GAB2	GRB2-associated-binding protein 2 isoform X1. (678 aa)
	SOCS2	Suppressor of cytokine signaling 2. (198 aa)
	SLA	Src-like-adapter isoform X1. (276 aa)
	FOXO3	Forkhead box protein O3. (672 aa)
	LOC111165935	Ras-like protein isoform X1. (285 aa)
	ABL2	Tyrosine-protein kinase. (1174 aa)
	CBL	E3 ubiquitin-protein ligase CBL isoform X1. (910 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	ERAS	GTPase ERas. (233 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	FLT3	Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
	LCK	Tyrosine-protein kinase. (509 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL2	CBL	A0A2Y9LZ58	A0A2Y9M339	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL isoform X1.	0.610
ABL2	FLT3	A0A2Y9LZ58	A0A2Y9N7L9	Tyrosine-protein kinase.	Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.565
ABL2	GRB2	A0A2Y9LZ58	A0A2Y9PJ90	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2.	0.610
CBL	ABL2	A0A2Y9M339	A0A2Y9LZ58	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.610
CBL	CSK	A0A2Y9M339	A0A2Y9NNZ0	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.747
CBL	FLT3	A0A2Y9M339	A0A2Y9N7L9	E3 ubiquitin-protein ligase CBL isoform X1.	Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.635
CBL	GRB2	A0A2Y9M339	A0A2Y9PJ90	E3 ubiquitin-protein ligase CBL isoform X1.	Growth factor receptor-bound protein 2.	0.997
CBL	LCK	A0A2Y9M339	A0A2Y9NNB7	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.789
CBL	LOC111186270	A0A2Y9M339	A0A2Y9Q410	E3 ubiquitin-protein ligase CBL isoform X1.	GRB2-related adapter protein 2 isoform X1.	0.717
CBL	LOC111186271	A0A2Y9M339	A0A2Y9Q010	E3 ubiquitin-protein ligase CBL isoform X1.	GRB2-related adapter protein 2-like isoform X1.	0.717
CBL	PIK3CA	A0A2Y9M339	A0A2Y9MZW2	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.867
CBL	PIK3R1	A0A2Y9M339	A0A2Y9Q8T5	E3 ubiquitin-protein ligase CBL isoform X1.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.987
CBL	RPS27A	A0A2Y9M339	A0A2Y9Q1L7	E3 ubiquitin-protein ligase CBL isoform X1.	ubiquitin-40S ribosomal protein S27a.	0.841
CBL	SH2B3	A0A2Y9M339	A0A2Y9Q391	E3 ubiquitin-protein ligase CBL isoform X1.	SH2B adapter protein 3 isoform X1.	0.640
CBL	SLA	A0A2Y9M339	A0A2Y9LJQ2	E3 ubiquitin-protein ligase CBL isoform X1.	Src-like-adapter isoform X1.	0.737
CBL	SLA2	A0A2Y9M339	A0A2Y9PYG1	E3 ubiquitin-protein ligase CBL isoform X1.	Src-like-adapter 2 isoform X1.	0.989
CBL	SOCS6	A0A2Y9M339	A0A2Y9PBZ1	E3 ubiquitin-protein ligase CBL isoform X1.	Suppressor of cytokine signaling 6.	0.520
CBL	SOS1	A0A2Y9M339	A0A2Y9N647	E3 ubiquitin-protein ligase CBL isoform X1.	Son of sevenless homolog 1 isoform X1.	0.566
CBL	SYK	A0A2Y9M339	A0A2Y9MGM5	E3 ubiquitin-protein ligase CBL isoform X1.	Tyrosine-protein kinase.	0.955
CDKN1B	FLT3	A0A2Y9NV03	A0A2Y9N7L9	Cyclin-dependent kinase inhibitor 1B.	Receptor-type tyrosine-protein kinase FLT3 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.742