24 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTGFRN	Prostaglandin F2 receptor negative regulator. (879 aa)
	ROBO1	Roundabout homolog 1 isoform X1. (1685 aa)
	BTNL2	Butyrophilin-like protein 2. (454 aa)
	SIRPA	Tyrosine-protein phosphatase non-receptor type substrate 1 isoform X1. (504 aa)
	CD4	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (455 aa)
	LOC111184480	TCR gamma alternate reading frame protein. (343 aa)
	HAPLN1	Hyaluronan and proteoglycan link protein 1. (354 aa)
	VPREB3	pre-B lymphocyte protein 3. (121 aa)
	LOC111162995	Immunoglobulin iota chain-like. (146 aa)
	LOC111163081	LOW QUALITY PROTEIN: immunoglobulin lambda-1 light chain-like. (235 aa)
	VSIG1	V-set and immunoglobulin domain-containing protein 1. (378 aa)
	MPZL1	Myelin protein zero-like protein 1 isoform X1. (269 aa)
	GPA33	Cell surface A33 antigen. (319 aa)
	BCAN	Brevican core protein isoform X1. (909 aa)
	CD8A	T-cell surface glycoprotein CD8 alpha chain isoform X1. (239 aa)
	CD8B	T-cell surface glycoprotein CD8 beta chain. (210 aa)
	NECTIN1	Nectin-1. (416 aa)
	MOG	Myelin-oligodendrocyte glycoprotein isoform X1. (253 aa)
	BTN3A3	Butyrophilin subfamily 3 member A3 isoform X1. (630 aa)
	MPZL2	Myelin protein zero-like protein 2 isoform X1. (215 aa)
	MPZ	Myelin protein P0. (285 aa)
	F11R	Junctional adhesion molecule A. (299 aa)
	CD86	T-lymphocyte activation antigen CD86 isoform X1. (344 aa)
	PDCD1	Programmed cell death protein 1 isoform X1. (288 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	CD86	Q9XS78	A0A2Y9MK30	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	T-lymphocyte activation antigen CD86 isoform X1.	0.923
CD4	CD8A	Q9XS78	A0A2Y9M2X3	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	T-cell surface glycoprotein CD8 alpha chain isoform X1.	0.986
CD4	CD8B	Q9XS78	A0A2Y9M310	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	T-cell surface glycoprotein CD8 beta chain.	0.984
CD4	F11R	Q9XS78	A0A2Y9MCT7	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Junctional adhesion molecule A.	0.477
CD4	MOG	Q9XS78	A0A2Y9M6V1	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Myelin-oligodendrocyte glycoprotein isoform X1.	0.864
CD4	PDCD1	Q9XS78	A0A2Y9MSN4	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Programmed cell death protein 1 isoform X1.	0.807
CD86	CD4	A0A2Y9MK30	Q9XS78	T-lymphocyte activation antigen CD86 isoform X1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.923
CD86	CD8A	A0A2Y9MK30	A0A2Y9M2X3	T-lymphocyte activation antigen CD86 isoform X1.	T-cell surface glycoprotein CD8 alpha chain isoform X1.	0.433
CD86	CD8B	A0A2Y9MK30	A0A2Y9M310	T-lymphocyte activation antigen CD86 isoform X1.	T-cell surface glycoprotein CD8 beta chain.	0.483
CD86	PDCD1	A0A2Y9MK30	A0A2Y9MSN4	T-lymphocyte activation antigen CD86 isoform X1.	Programmed cell death protein 1 isoform X1.	0.514
CD8A	CD4	A0A2Y9M2X3	Q9XS78	T-cell surface glycoprotein CD8 alpha chain isoform X1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.986
CD8A	CD86	A0A2Y9M2X3	A0A2Y9MK30	T-cell surface glycoprotein CD8 alpha chain isoform X1.	T-lymphocyte activation antigen CD86 isoform X1.	0.433
CD8A	CD8B	A0A2Y9M2X3	A0A2Y9M310	T-cell surface glycoprotein CD8 alpha chain isoform X1.	T-cell surface glycoprotein CD8 beta chain.	0.999
CD8A	PDCD1	A0A2Y9M2X3	A0A2Y9MSN4	T-cell surface glycoprotein CD8 alpha chain isoform X1.	Programmed cell death protein 1 isoform X1.	0.404
CD8B	CD4	A0A2Y9M310	Q9XS78	T-cell surface glycoprotein CD8 beta chain.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.984
CD8B	CD86	A0A2Y9M310	A0A2Y9MK30	T-cell surface glycoprotein CD8 beta chain.	T-lymphocyte activation antigen CD86 isoform X1.	0.483
CD8B	CD8A	A0A2Y9M310	A0A2Y9M2X3	T-cell surface glycoprotein CD8 beta chain.	T-cell surface glycoprotein CD8 alpha chain isoform X1.	0.999
CD8B	PDCD1	A0A2Y9M310	A0A2Y9MSN4	T-cell surface glycoprotein CD8 beta chain.	Programmed cell death protein 1 isoform X1.	0.418
F11R	CD4	A0A2Y9MCT7	Q9XS78	Junctional adhesion molecule A.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.477
LOC111162995	LOC111163081	A0A2Y9LEC5	A0A2Y9LPM6	Immunoglobulin iota chain-like.	LOW QUALITY PROTEIN: immunoglobulin lambda-1 light chain-like.	0.871