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IMPA2 IMPA2 INPP5J INPP5J MTMR4 MTMR4 PLCD1 PLCD1 PI4KA PI4KA MTMR3 MTMR3 SYNJ1 SYNJ1 LOC111163199 LOC111163199 PLCB1 PLCB1 FIG4 FIG4 PIK3CG PIK3CG PLCB4 PLCB4 PIK3C2A PIK3C2A ISYNA1 ISYNA1 PIP4K2B PIP4K2B IMPA1 IMPA1 MTM1 MTM1 SYNJ2 SYNJ2 OCRL OCRL PIP5K1C PIP5K1C PIK3C3 PIK3C3 PIP5K1A PIP5K1A PI4KB PI4KB MTMR1 MTMR1 MTMR2 MTMR2 INPP1 INPP1 IPPK IPPK PI4K2B PI4K2B INPP5F INPP5F INPP5A INPP5A INPPL1 INPPL1 PI4K2A PI4K2A MTMR14 MTMR14 PLCD3 PLCD3 IPMK IPMK PLCD4 PLCD4 INPP5D INPP5D PIK3CA PIK3CA PIKFYVE PIKFYVE PIP5K1B PIP5K1B MTMR7 MTMR7 MTMR6 MTMR6 PLCE1 PLCE1 PTEN PTEN MINPP1 MINPP1 SACM1L SACM1L INPP5B INPP5B PIP4K2C PIP4K2C TPI1 TPI1 PIP5KL1 PIP5KL1 ITPK1 ITPK1 PLCZ1 PLCZ1 ALDH6A1 ALDH6A1 ITPKB ITPKB PLCH1 PLCH1 PIK3C2G PIK3C2G INPP5E INPP5E PIP4K2A PIP4K2A PLCG2 PLCG2 PIK3CB PIK3CB ITPKC ITPKC PLCB2 PLCB2 LOC111180171 LOC111180171 CDIPT CDIPT ITPKA ITPKA PLCG1 PLCG1 PLCB3 PLCB3 PIK3C2B PIK3C2B INPP5K INPP5K MIOX MIOX LOC111187172 LOC111187172 PIK3CD PIK3CD LOC111187436 LOC111187436 INPP4B INPP4B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IMPA2Inositol-1-monophosphatase. (288 aa)
INPP5JPhosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1. (980 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1211 aa)
PLCD1Phosphoinositide phospholipase C. (817 aa)
PI4KAPhosphatidylinositol 4-kinase alpha isoform X1; Belongs to the PI3/PI4-kinase family. (2149 aa)
MTMR3Myotubularin-related protein 3 isoform X1. (1202 aa)
SYNJ1Synaptojanin-1 isoform X2. (1592 aa)
LOC111163199LOW QUALITY PROTEIN: phosphatidylinositide phosphatase SAC1-like. (535 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
FIG4Polyphosphoinositide phosphatase isoform X1. (907 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PIK3C2APhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1711 aa)
ISYNA1Inositol-3-phosphate synthase 1. (557 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
MTM1Myotubularin isoform X1. (603 aa)
SYNJ2Synaptojanin-2 isoform X1. (1478 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (893 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1. (718 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
PI4KBPhosphatidylinositol 4-kinase beta isoform X1; Belongs to the PI3/PI4-kinase family. (832 aa)
MTMR1Myotubularin-related protein 1 isoform X1. (685 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
INPP1Inositol polyphosphate 1-phosphatase. (402 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (547 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2-beta. (488 aa)
INPP5FPhosphatidylinositide phosphatase SAC2 isoform X1. (1173 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (534 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
PI4K2APhosphatidylinositol 4-kinase type 2-alpha. (479 aa)
MTMR14Myotubularin-related protein 14 isoform X1. (648 aa)
PLCD3Phosphoinositide phospholipase C. (784 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (419 aa)
PLCD4Phosphoinositide phospholipase C. (821 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta. (540 aa)
MTMR7Myotubularin-related protein 7 isoform X1. (660 aa)
MTMR6Myotubularin-related protein 6. (622 aa)
PLCE1Phosphoinositide phospholipase C. (1811 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
MINPP1Multiple inositol polyphosphate phosphatase 1 isoform X1; Belongs to the histidine acid phosphatase family. (486 aa)
SACM1LPhosphatidylinositide phosphatase SAC1 isoform X1. (587 aa)
INPP5BType II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1. (994 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (421 aa)
TPI1Triosephosphate isomerase. (286 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1. (413 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase isoform X1. (419 aa)
PLCZ1Phosphoinositide phospholipase C. (502 aa)
ALDH6A1Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform X1. (537 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (941 aa)
PLCH1Phosphoinositide phospholipase C. (1685 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1483 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (627 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (461 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (685 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
LOC111180171LOW QUALITY PROTEIN: phosphatidylinositide phosphatase SAC2-like. (615 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (213 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (460 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (476 aa)
MIOXInositol oxygenase. (269 aa)
LOC111187172Phosphoinositide phospholipase C. (1150 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
LOC111187436Type I inositol 3,4-bisphosphate 4-phosphatase isoform X4. (974 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase isoform X2. (754 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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