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TUBB6 TUBB6 LOC111163074 LOC111163074 EEA1 EEA1 STX12 STX12 MPO MPO LOC111162959 LOC111162959 ATP6V0D2 ATP6V0D2 DYNC1LI1 DYNC1LI1 LOC111164621 LOC111164621 CD209 CD209 TUBB4A TUBB4A RAB5C RAB5C ATP6V1A ATP6V1A ATP6V1C2 ATP6V1C2 LOC111166690 LOC111166690 COMP COMP ATP6V0A1 ATP6V0A1 LOC111164620 LOC111164620 LOC111166812 LOC111166812 RAB5A RAB5A STX7 STX7 ATP6V1H ATP6V1H THBS3 THBS3 CTSL CTSL C3 C3 THBS2 THBS2 ATP6V1B1 ATP6V1B1 COLEC11 COLEC11 LAMP2 LAMP2 SEC61A1 SEC61A1 CANX CANX CALR CALR PIK3C3 PIK3C3 CTSS CTSS LOC111170121 LOC111170121 ACTB ACTB DYNC2H1 DYNC2H1 RAB7A RAB7A ATP6V1B2 ATP6V1B2 ATP6V1G3 ATP6V1G3 LOC111170644 LOC111170644 LOC111171851 LOC111171851 ITGB5 ITGB5 STX18 STX18 ITGAV ITGAV LOC111170413 LOC111170413 TLR6 TLR6 TUBB TUBB MBL2 MBL2 DYNC1I2 DYNC1I2 LOC111170450 LOC111170450 ATP6V1D ATP6V1D ATP6V1G2 ATP6V1G2 TFRC TFRC ATP6AP1 ATP6AP1 PIKFYVE PIKFYVE TUBA4A TUBA4A RAB5B RAB5B LOC111174050 LOC111174050 PLA2R1 PLA2R1 MSR1 MSR1 DYNC1H1 DYNC1H1 LOC111176754 LOC111176754 LOC111174051 LOC111174051 LAMP1 LAMP1 ATP6V0B ATP6V0B TUBA8 TUBA8 C1R C1R M6PR M6PR TLR4 TLR4 TUBB4B TUBB4B MRC1 MRC1 ATP6V1E1 ATP6V1E1 ATP6V1F ATP6V1F LOC111178659 LOC111178659 LOC111178664 LOC111178664 LOC111178928 LOC111178928 LOC111178931 LOC111178931 SEC61A2 SEC61A2 LOC111178668 LOC111178668 ATP6V1G1 ATP6V1G1 LOC111179403 LOC111179403 LOC111176755 LOC111176755 LOC111178925 LOC111178925 LOC111178929 LOC111178929 TAP1 TAP1 ATP6V0E2 ATP6V0E2 ITGB1 ITGB1 ATP6V1C1 ATP6V1C1 LOC111178666 LOC111178666 FCAR FCAR DYNC1I1 DYNC1I1 COLEC12 COLEC12 LOC111178927 LOC111178927 ATP6V0D1 ATP6V0D1 DYNC1LI2 DYNC1LI2 LOC111181312 LOC111181312 SEC22B SEC22B NCF1 NCF1 ITGB3 ITGB3 ITGAM ITGAM TUBB2A TUBB2A HGS HGS ACTG1 ACTG1 LOC111183561 LOC111183561 ATP6V0A4 ATP6V0A4 LOC111183594 LOC111183594 MRC2 MRC2 LOC111181737 LOC111181737 THBS1 THBS1 RAC1 RAC1 CORO1A CORO1A CD14 CD14 NCF2 NCF2 THBS4 THBS4 MARCO MARCO SFTPD SFTPD RAB7B RAB7B TCIRG1 TCIRG1 SEC61G SEC61G RILP RILP ATP6V0E1 ATP6V0E1 ATP6V0C ATP6V0C TUBB1 TUBB1 ATP6V0A2 ATP6V0A2 SCARB1 SCARB1 LOC111186386 LOC111186386 ITGB2 ITGB2 ITGA2 ITGA2 LOC111187847 LOC111187847 NOS1 NOS1 VAMP3 VAMP3 TLR2 TLR2 SEC61B SEC61B
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
LOC111163074Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa)
EEA1Early endosome antigen 1 isoform X1. (1453 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (274 aa)
MPOMyeloperoxidase. (719 aa)
LOC111162959Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
LOC111164621Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
CD209CD209 antigen. (279 aa)
TUBB4ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
RAB5CRas-related protein Rab-5C. (216 aa)
ATP6V1ALOW QUALITY PROTEIN: V-type proton ATPase catalytic subunit A. (621 aa)
ATP6V1C2V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (427 aa)
LOC111166690H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (559 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa)
LOC111164620Platelet glycoprotein 4-like; Belongs to the CD36 family. (472 aa)
LOC111166812Cathepsin L1; Belongs to the peptidase C1 family. (334 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
STX7Syntaxin-7 isoform X1; Belongs to the syntaxin family. (261 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa)
THBS3Thrombospondin-3 isoform X4. (957 aa)
CTSLCathepsin L1; Belongs to the peptidase C1 family. (333 aa)
C3Complement C3 isoform X1. (1695 aa)
THBS2Thrombospondin-2. (1171 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
COLEC11Collectin-11. (267 aa)
LAMP2Lysosome-associated membrane glycoprotein 2 isoform X1. (411 aa)
SEC61A1Protein transport protein Sec61 subunit alpha isoform X1. (476 aa)
CANXCalnexin. (593 aa)
CALRCalreticulin. (417 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (340 aa)
LOC111170121Tubulin alpha chain-like 3; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (286 aa)
ACTBActin, cytoplasmic 1. (375 aa)
DYNC2H1Cytoplasmic dynein 2 heavy chain 1. (4307 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (198 aa)
LOC111170644BOLA class I histocompatibility antigen, alpha chain BL3-7-like isoform X1; Belongs to the MHC class I family. (360 aa)
LOC111171851Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (425 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
STX18Syntaxin-18 isoform X1. (335 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
LOC111170413Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1. (278 aa)
TLR6Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa)
TUBBTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (444 aa)
MBL2LOW QUALITY PROTEIN: mannose-binding protein C. (244 aa)
DYNC1I2LOW QUALITY PROTEIN: cytoplasmic dynein 1 intermediate chain 2. (612 aa)
LOC111170450Cytochrome b-245 heavy chain isoform X1. (570 aa)
ATP6V1DV-type proton ATPase subunit D isoform X1. (247 aa)
ATP6V1G2V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
TFRCTransferrin receptor protein 1 isoform X1. (772 aa)
ATP6AP1V-type proton ATPase subunit S1. (469 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2110 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
RAB5BRas-related protein Rab-5B. (215 aa)
LOC111174050Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PLA2R1Secretory phospholipase A2 receptor. (1389 aa)
MSR1Macrophage scavenger receptor types I and II isoform X1. (454 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (4645 aa)
LOC111176754C-type lectin domain family 7 member A-like isoform X1. (244 aa)
LOC111174051Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (411 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit isoform X1; Belongs to the V-ATPase proteolipid subunit family. (233 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (496 aa)
C1RComplement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (713 aa)
M6PRCation-dependent mannose-6-phosphate receptor isoform X1. (316 aa)
TLR4Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
MRC1Macrophage mannose receptor 1. (1455 aa)
ATP6V1E1V-type proton ATPase subunit E 1. (226 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC111178659Antigen peptide transporter 2-like isoform X4. (758 aa)
LOC111178664HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa)
LOC111178928DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
LOC111178931HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa)
SEC61A2Protein transport protein Sec61 subunit alpha isoform X1. (476 aa)
LOC111178668HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
LOC111179403Cytochrome b-245 light chain isoform X1. (202 aa)
LOC111176755Oxidized low-density lipoprotein receptor 1-like isoform X1. (273 aa)
LOC111178925boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa)
LOC111178929HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa)
TAP1Antigen peptide transporter 1 isoform X1. (750 aa)
ATP6V0E2V-type proton ATPase subunit e 2. (112 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
LOC111178666HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (261 aa)
FCARImmunoglobulin alpha Fc receptor isoform X1. (290 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa)
COLEC12Collectin-12. (742 aa)
LOC111178927HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
LOC111181312Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
SEC22BVesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (215 aa)
NCF1Neutrophil cytosol factor 1 isoform X2. (405 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (872 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
LOC111183561Mannose-binding protein A-like isoform X1. (265 aa)
ATP6V0A4V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa)
LOC111183594Pulmonary surfactant-associated protein A. (283 aa)
MRC2C-type mannose receptor 2. (1446 aa)
LOC111181737Syntaxin-12-like; Belongs to the syntaxin family. (278 aa)
THBS1Thrombospondin-1. (1170 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (526 aa)
THBS4Thrombospondin-4. (961 aa)
MARCOMacrophage receptor MARCO isoform X1. (410 aa)
SFTPDPulmonary surfactant-associated protein D. (375 aa)
RAB7BRas-related protein Rab-7b isoform X1. (210 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa)
SEC61GProtein transport protein Sec61 subunit gamma. (68 aa)
RILPRab-interacting lysosomal protein isoform X1. (447 aa)
ATP6V0E1V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (485 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (867 aa)
SCARB1Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (511 aa)
LOC111186386Neutrophil cytosol factor 4-like. (250 aa)
ITGB2Integrin beta. (769 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
LOC111187847Neutrophil cytosol factor 4 isoform X2. (339 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1461 aa)
VAMP3Vesicle-associated membrane protein 3. (104 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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