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| | CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa) |
| | LOC111163175 | Cyclin-dependent kinase inhibitor 2A-like. (152 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2. (544 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (380 aa) |
| | E2F2 | Transcription factor E2F2 isoform X1. (437 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (131 aa) |
| | TRAF3IP2 | Adapter protein CIKS isoform X1. (564 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | E2F5 | Transcription factor E2F5 isoform X1. (365 aa) |
| | RBL2 | Retinoblastoma-like protein 2. (1083 aa) |
| | NFATC4 | LOW QUALITY PROTEIN: nuclear factor of activated T-cells, cytoplasmic 4. (901 aa) |
| | ETS1 | Protein C-ets-1 isoform X1. (486 aa) |
| | SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa) |
| | RRAS2 | Ras-related protein R-Ras2. (204 aa) |
| | LOC111166690 | H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (559 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | CDK1 | Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3064 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa) |
| | SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | LOC111169056 | LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase D-like. (370 aa) |
| | SQSTM1 | Sequestosome-1. (440 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | NFATC1 | Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (928 aa) |
| | CHEK1 | Serine/threonine-protein kinase Chk1 isoform X1. (540 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | LOC111170644 | BOLA class I histocompatibility antigen, alpha chain BL3-7-like isoform X1; Belongs to the MHC class I family. (360 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (522 aa) |
| | CCNB3 | LOW QUALITY PROTEIN: G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (1456 aa) |
| | BTRC | F-box/WD repeat-containing protein 1A isoform X1. (607 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E-binding protein 1. (118 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (524 aa) |
| | CACNA1D | Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa) |
| | VDAC3 | Voltage-dependent anion-selective channel protein 3. (283 aa) |
| | FOXO1 | Forkhead box protein O1. (663 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | ZFP36L1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | LIN52 | Protein lin-52 homolog isoform X1. (116 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | RBBP4 | Histone-binding protein RBBP4. (425 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | RHEB | GTP-binding protein Rheb. (184 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | CAPN2 | Calpain-2 catalytic subunit isoform X1; Belongs to the peptidase C2 family. (703 aa) |
| | FOXM1 | Forkhead box protein M1 isoform X1. (761 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (398 aa) |
| | ZFP36L2 | mRNA decay activator protein ZFP36L2. (493 aa) |
| | CALML4 | Calmodulin-like protein 4 isoform X1. (189 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | TSC1 | Hamartin. (1169 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | CALM1 | Calmodulin-1; Belongs to the calmodulin family. (149 aa) |
| | HIPK2 | Homeodomain-interacting protein kinase 2 isoform X1. (1248 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | TGFB3 | Transforming growth factor beta-3. (456 aa) |
| | MRAS | Ras-related protein M-Ras. (208 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2671 aa) |
| | HIPK3 | Homeodomain-interacting protein kinase 3 isoform X1. (1213 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | ATR | Serine/threonine-protein kinase ATR isoform X1; Belongs to the PI3/PI4-kinase family. (2655 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (727 aa) |
| | CCNE1 | G1/S-specific cyclin-E1 isoform X1; Belongs to the cyclin family. (410 aa) |
| | RRAS | Ras-related protein R-Ras isoform X1. (251 aa) |
| | PPID | Peptidyl-prolyl cis-trans isomerase D isoform X1. (383 aa) |
| | E2F4 | Transcription factor E2F4 isoform X1. (438 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | HIPK4 | Homeodomain-interacting protein kinase 4. (610 aa) |
| | HIPK1 | Homeodomain-interacting protein kinase 1 isoform X1. (1209 aa) |
| | NFATC3 | Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1073 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | RAD50 | DNA repair protein RAD50 isoform X1. (1344 aa) |
| | LIN37 | Protein lin-37 homolog isoform X1. (246 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (368 aa) |
| | E2F3 | LOW QUALITY PROTEIN: transcription factor E2F3. (461 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (420 aa) |
| | PPP1CA | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa) |
| | TRPM7 | Transient receptor potential cation channel subfamily M member 7. (1874 aa) |
| | CAPN1 | Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (716 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (735 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | SERPINE1 | Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | RBL1 | Retinoblastoma-like protein 1 isoform X2. (1073 aa) |
| | MYBL2 | Myb-related protein B. (700 aa) |
| | MCU | Calcium uniporter protein, mitochondrial isoform X1. (371 aa) |
| | VDAC2 | Voltage-dependent anion-selective channel protein 2. (294 aa) |
| | IGFBP3 | Insulin-like growth factor-binding protein 3. (293 aa) |
| | RASSF5 | Ras association domain-containing protein 5 isoform X1. (422 aa) |
| | MAPKAPK2 | LOW QUALITY PROTEIN: MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (414 aa) |
| | E2F1 | Transcription factor E2F1. (437 aa) |
| | GATA4 | Transcription factor GATA-4 isoform X1. (437 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | TSC2 | Tuberin isoform X8. (1815 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (456 aa) |
| | FBXW11 | F-box/WD repeat-containing protein 11 isoform X1. (563 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (413 aa) |
| | LIN54 | Protein lin-54 homolog isoform X1. (748 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | CALML6 | Calmodulin-like protein 6 isoform X2. (227 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | PPP3R1 | Calcineurin subunit B type 1. (170 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa) |
| | NFATC2 | Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (943 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | PPP3R2 | LOW QUALITY PROTEIN: calcineurin subunit B type 2. (231 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | RAD1 | Cell cycle checkpoint protein RAD1. (279 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (387 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
