STRINGSTRING
GP1BB GP1BB MYL12B MYL12B MAPK1 MAPK1 LOC111162912 LOC111162912 ADCY4 ADCY4 ADCY8 ADCY8 FYN FYN ADCY7 ADCY7 MYLK3 MYLK3 ROCK2 ROCK2 PLCB1 PLCB1 GNAI1 GNAI1 PIK3CG PIK3CG PLCB4 PLCB4 F2RL3 F2RL3 VAMP8 VAMP8 PIK3R2 PIK3R2 FCER1G FCER1G PRKACA PRKACA LYN LYN GUCY1A2 GUCY1A2 TBXA2R TBXA2R COL1A1 COL1A1 PPP1R12A PPP1R12A ARHGEF12 ARHGEF12 ACTB ACTB ITGA2B ITGA2B SYK SYK GP9 GP9 STIM1 STIM1 COL3A1 COL3A1 ADCY5 ADCY5 PIK3CA PIK3CA ITPR1 ITPR1 GNAI2 GNAI2 PRKCI PRKCI ADCY3 ADCY3 PRKG1 PRKG1 GP5 GP5 PPP1CB PPP1CB PIK3R3 PIK3R3 RHOA RHOA AKT1 AKT1 RAP1B RAP1B NOS3 NOS3 ITPR2 ITPR2 ADCY6 ADCY6 PTGS1 PTGS1 GNAQ GNAQ AKT3 AKT3 APBB1IP APBB1IP MAPK14 MAPK14 BTK BTK MAPK13 MAPK13 VWF VWF PRKACB PRKACB GUCY1A3 GUCY1A3 TBXAS1 TBXAS1 P2RY1 P2RY1 PLCG2 PLCG2 ITGB1 ITGB1 PIK3CB PIK3CB P2RY12 P2RY12 TLN2 TLN2 ITPR3 ITPR3 RAP1A RAP1A ADCY2 ADCY2 VASP VASP GP6 GP6 GUCY1B3 GUCY1B3 ARHGAP35 ARHGAP35 PTGIR PTGIR PLA2G4F PLA2G4F PLCB2 PLCB2 ROCK1 ROCK1 GNAI3 GNAI3 SNAP23 SNAP23 PLA2G4E PLA2G4E ITGB3 ITGB3 RASGRP1 RASGRP1 AKT2 AKT2 MAPK3 MAPK3 GNA13 GNA13 ARHGEF1 ARHGEF1 COL1A2 COL1A2 ACTG1 ACTG1 PPP1CA PPP1CA FERMT3 FERMT3 PLCB3 PLCB3 SRC SRC ADCY1 ADCY1 RASGRP2 RASGRP2 F2 F2 P2RX1 P2RX1 MYLK2 MYLK2 PLA2G4A PLA2G4A F2R F2R ADCY9 ADCY9 MAPK12 MAPK12 LCP2 LCP2 ORAI1 ORAI1 PPP1CC PPP1CC FGB FGB PIK3R1 PIK3R1 PIK3R5 PIK3R5 PIK3R6 PIK3R6 PRKCZ PRKCZ MAPK11 MAPK11 PRKG2 PRKG2 FGA FGA FGG FGG GNAS GNAS ITGA2 ITGA2 PIK3CD PIK3CD TLN1 TLN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GP1BBPlatelet glycoprotein Ib beta chain. (205 aa)
MYL12BMyosin regulatory light chain 12B. (172 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
LOC111162912Myosin regulatory light chain 12B. (171 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1237 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
FYNTyrosine-protein kinase. (537 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
ROCK2Rho-associated protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1416 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (380 aa)
VAMP8Vesicle-associated membrane protein 8. (100 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (86 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
LYNTyrosine-protein kinase. (518 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (726 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
COL1A1Collagen alpha-1(I) chain. (1463 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1030 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1544 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa)
SYKTyrosine-protein kinase. (626 aa)
GP9Platelet glycoprotein IX. (177 aa)
STIM1Stromal interaction molecule 1 isoform X1. (717 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (707 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1150 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
GP5Platelet glycoprotein V. (569 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
RHOATransforming protein RhoA. (193 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
RAP1BRas-related protein Rap-1b. (184 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
PTGS1Prostaglandin G/H synthase 1 isoform X1. (600 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (359 aa)
AKT3Non-specific serine/threonine protein kinase. (541 aa)
APBB1IPAmyloid beta A4 precursor protein-binding family B member 1-interacting protein. (654 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
BTKTyrosine-protein kinase. (687 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
VWFVon Willebrand factor. (2806 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
TBXAS1thromboxane-A synthase isoform X1; Belongs to the cytochrome P450 family. (585 aa)
P2RY1P2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
P2RY12P2Y purinoceptor 12. (339 aa)
TLN2Talin-2 isoform X1. (2554 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2671 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
VASPVasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (384 aa)
GP6Platelet glycoprotein VI isoform X1. (464 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
PLA2G4FPhospholipase A2. (849 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
PLA2G4EPhospholipase A2. (868 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (870 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (377 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1 isoform X1. (998 aa)
COL1A2Collagen alpha-2(I) chain. (1366 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
FERMT3Fermitin family homolog 3. (663 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
SRCTyrosine-protein kinase. (562 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X1. (684 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (623 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
MYLK2Myosin light chain kinase 2, skeletal/cardiac muscle. (615 aa)
PLA2G4APhospholipase A2. (749 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
MAPK12Mitogen-activated protein kinase. (456 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X1. (534 aa)
ORAI1Calcium release-activated calcium channel protein 1. (410 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
FGBFibrinogen beta chain isoform X1. (495 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5 isoform X1. (871 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6 isoform X1. (881 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
MAPK11Mitogen-activated protein kinase. (366 aa)
PRKG2cGMP-dependent protein kinase. (792 aa)
FGAFibrinogen alpha chain. (852 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1023 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
TLN1Talin-1. (2541 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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