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MAPK1 | Mitogen-activated protein kinase. (380 aa) | ||||
LOC111163731 | C-C motif chemokine. (93 aa) | ||||
IFNAR1 | Interferon alpha/beta receptor 1 isoform X1. (561 aa) | ||||
IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (594 aa) | ||||
LOC111163732 | C-C motif chemokine. (92 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) | ||||
CCL5 | C-C motif chemokine. (91 aa) | ||||
LOC111163733 | C-C motif chemokine. (90 aa) | ||||
LOC111163130 | Interferon alpha-1-like. (226 aa) | ||||
TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (226 aa) | ||||
MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa) | ||||
MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (458 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) | ||||
TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) | ||||
TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (707 aa) | ||||
TLR7 | Toll-like receptor 7 isoform X1. (1086 aa) | ||||
TLR8 | Toll-like receptor 8; Belongs to the Toll-like receptor family. (1035 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (464 aa) | ||||
MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) | ||||
CTSK | Cathepsin K isoform X1; Belongs to the peptidase C1 family. (358 aa) | ||||
IRF7 | Interferon regulatory factor 7 isoform X1. (473 aa) | ||||
CD40 | Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa) | ||||
CD80 | T-lymphocyte activation antigen CD80 isoform X1. (295 aa) | ||||
IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) | ||||
TLR1 | Toll-like receptor 1; Belongs to the Toll-like receptor family. (796 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
CD86 | T-lymphocyte activation antigen CD86 isoform X1. (344 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
TOLLIP | Toll-interacting protein isoform X1. (273 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (749 aa) | ||||
CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) | ||||
TLR6 | Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa) | ||||
IKBKG | NF-kappa-B essential modulator isoform X1. (412 aa) | ||||
LOC111171121 | Interferon alpha-1-like. (133 aa) | ||||
LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) | ||||
TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa) | ||||
IFNB1 | Interferon beta. (185 aa) | ||||
IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) | ||||
TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) | ||||
PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) | ||||
NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) | ||||
JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa) | ||||
TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) | ||||
FOS | Proto-oncogene c-Fos. (380 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) | ||||
TLR5 | Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase. (541 aa) | ||||
TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) | ||||
MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (468 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) | ||||
MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) | ||||
IRF5 | Interferon regulatory factor 5 isoform X1. (517 aa) | ||||
IRF3 | Interferon regulatory factor 3 isoform X1. (464 aa) | ||||
SPP1 | Osteopontin. (362 aa) | ||||
NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) | ||||
RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (687 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) | ||||
MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (368 aa) | ||||
RAC1 | Ras-related C3 botulinum toxin substrate 1. (192 aa) | ||||
FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) | ||||
CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) | ||||
RELA | Transcription factor p65 isoform X1. (562 aa) | ||||
TICAM2 | TIR domain-containing adapter molecule 2. (235 aa) | ||||
LBP | Lipopolysaccharide-binding protein isoform X1. (537 aa) | ||||
MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X4; Belongs to the protein kinase superfamily. (410 aa) | ||||
LY96 | Lymphocyte antigen 96. (160 aa) | ||||
TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (504 aa) | ||||
IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (807 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (456 aa) | ||||
CXCL10 | C-X-C motif chemokine. (103 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (366 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa) | ||||
CXCL11 | C-X-C motif chemokine 11. (100 aa) | ||||
PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) | ||||
CXCL9 | C-X-C motif chemokine. (160 aa) | ||||
TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |