67 items (Delphinapterus leucas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAPK1	Mitogen-activated protein kinase. (380 aa)
	VAV1	Proto-oncogene vav isoform X1. (845 aa)
	MAP2K2	Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
	LYN	Tyrosine-protein kinase. (518 aa)
	GSK3B	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
	NFATC1	Nuclear factor of activated T-cells, cytoplasmic 1 isoform X1. (928 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	CARD11	Caspase recruitment domain-containing protein 11 isoform X1. (1154 aa)
	RAF1	RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (522 aa)
	INPPL1	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1. (1264 aa)
	IKBKG	NF-kappa-B essential modulator isoform X1. (412 aa)
	INPP5D	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1150 aa)
	SOS2	Son of sevenless homolog 2 isoform X1. (1332 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	CHUK	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
	IKBKB	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa)
	SOS1	Son of sevenless homolog 1 isoform X1. (1333 aa)
	RASGRP3	Ras guanyl-releasing protein 3 isoform X1. (692 aa)
	PIK3AP1	Phosphoinositide 3-kinase adapter protein 1 isoform X1. (806 aa)
	BLNK	B-cell linker protein isoform X1. (528 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
	NFKBIA	NF-kappa-B inhibitor alpha. (314 aa)
	JUN	Transcription factor AP-1; Belongs to the bZIP family. (343 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	KRAS	GTPase KRas. (188 aa)
	VAV2	Guanine nucleotide exchange factor VAV2 isoform X1. (879 aa)
	FOS	Proto-oncogene c-Fos. (380 aa)
	AKT3	Non-specific serine/threonine protein kinase. (541 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	BTK	Tyrosine-protein kinase. (687 aa)
	NFKBIE	NF-kappa-B inhibitor epsilon isoform X1. (365 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	DAPP1	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1. (280 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	CD79A	B-cell antigen receptor complex-associated protein alpha chain. (223 aa)
	NFKBIB	NF-kappa-B inhibitor beta. (353 aa)
	BCL10	B-cell lymphoma/leukemia 10. (233 aa)
	VAV3	Guanine nucleotide exchange factor VAV3. (954 aa)
	NFKB1	Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
	CD22	B-cell receptor CD22. (843 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	NFATC3	Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1073 aa)
	MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa)
	CD19	B-lymphocyte antigen CD19 isoform X1. (570 aa)
	NRAS	GTPase NRas. (189 aa)
	RAC3	Ras-related C3 botulinum toxin substrate 3 isoform X1. (192 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
	PRKCB	Protein kinase C. (689 aa)
	CD79B	B-cell antigen receptor complex-associated protein beta chain isoform X1. (230 aa)
	CD81	Tetraspanin. (236 aa)
	GRB2	Growth factor receptor-bound protein 2. (217 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1. (192 aa)
	PPP3CB	Serine/threonine-protein phosphatase. (525 aa)
	RELA	Transcription factor p65 isoform X1. (562 aa)
	CR2	Complement receptor type 2 isoform X1. (1471 aa)
	RAC2	Ras-related C3 botulinum toxin substrate 2 isoform X2. (192 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	PPP3R1	Calcineurin subunit B type 1. (170 aa)
	NFATC2	Nuclear factor of activated T-cells, cytoplasmic 2 isoform X1. (943 aa)
	PPP3R2	LOW QUALITY PROTEIN: calcineurin subunit B type 2. (231 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
	CD72	B-cell differentiation antigen CD72. (364 aa)

Your Current Organism:

Delphinapterus leucas

NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	A0A2Y9NBQ2	A0A2Y9PDM4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	AKT3	A0A2Y9NBQ2	A0A2Y9NJE3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.901
AKT1	CHUK	A0A2Y9NBQ2	A0A2Y9N087	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1.	0.970
AKT1	DAPP1	A0A2Y9NBQ2	A0A2Y9NYU8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1.	0.434
AKT1	GSK3B	A0A2Y9NBQ2	A0A2Y9ME39	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily.	0.952
AKT1	IKBKB	A0A2Y9NBQ2	A0A2Y9N1I7	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1.	0.960
AKT1	IKBKG	A0A2Y9NBQ2	A0A2Y9MTM9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NF-kappa-B essential modulator isoform X1.	0.929
AKT1	JUN	A0A2Y9NBQ2	A0A2Y9NBA9	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Transcription factor AP-1; Belongs to the bZIP family.	0.926
AKT1	KRAS	A0A2Y9NBQ2	A0A2Y9NF08	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	GTPase KRas.	0.476
AKT1	LYN	A0A2Y9NBQ2	A0A2Y9LZZ2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.470
AKT1	MAPK1	A0A2Y9NBQ2	A0A2Y9LEH4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.929
AKT1	MAPK3	A0A2Y9NBQ2	A0A2Y9PDR5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.937
AKT1	NRAS	A0A2Y9NBQ2	A0A2Y9PBA0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	GTPase NRas.	0.410
AKT1	PIK3CA	A0A2Y9NBQ2	A0A2Y9MZW2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.965
AKT1	PIK3CB	A0A2Y9NBQ2	A0A2Y9NZC3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.961
AKT1	PIK3CD	A0A2Y9NBQ2	A0A2Y9QGK3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.949
AKT1	PIK3R1	A0A2Y9NBQ2	A0A2Y9Q8T5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.964
AKT1	PIK3R2	A0A2Y9NBQ2	A0A2Y9LXY5	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.952
AKT1	PIK3R3	A0A2Y9NBQ2	A0A2Y9NAQ0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1.	0.946
AKT1	RAF1	A0A2Y9NBQ2	A0A2Y9MMZ0	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RAF proto-oncogene serine/threonine-protein kinase isoform X1.	0.928