STRINGSTRING
GNGT2 GNGT2 GRIN2A GRIN2A MAPK1 MAPK1 DLGAP1 DLGAP1 GNG4 GNG4 GRK3 GRK3 GRIK2 GRIK2 ADCY4 ADCY4 ADCY8 ADCY8 ADCY7 ADCY7 PLCB1 PLCB1 GNAI1 GNAI1 PLCB4 PLCB4 GNAO1 GNAO1 GRM1 GRM1 GNG14 GNG14 HOMER2 HOMER2 PRKACA PRKACA GRIK4 GRIK4 GRIA4 GRIA4 HOMER3 HOMER3 GLUL GLUL SLC1A6 SLC1A6 CACNA1A CACNA1A GRM6 GRM6 GRIA3 GRIA3 GRM7 GRM7 LOC111171236 LOC111171236 GLS GLS PPP3CC PPP3CC ADCY5 ADCY5 GRIN3B GRIN3B GRIK1 GRIK1 GNG7 GNG7 KCNJ3 KCNJ3 SLC38A2 SLC38A2 ITPR1 ITPR1 PLD1 PLD1 GNB4 GNB4 GLS2 GLS2 GNAI2 GNAI2 SLC38A1 SLC38A1 ADCY3 ADCY3 CACNA1D CACNA1D SLC38A3 SLC38A3 SLC1A1 SLC1A1 GNG2 GNG2 GRM2 GRM2 SLC1A7 SLC1A7 ITPR2 ITPR2 ADCY6 ADCY6 CACNA1C CACNA1C GRIK3 GRIK3 GNAQ GNAQ LOC111176690 LOC111176690 GRIN2B GRIN2B GNB5 GNB5 LOC111177332 LOC111177332 PRKACB PRKACB GRIN1 GRIN1 SLC1A2 SLC1A2 SLC17A6 SLC17A6 SLC17A7 SLC17A7 GRIN2D GRIN2D ITPR3 ITPR3 GRM4 GRM4 GRIK5 GRIK5 GNG5 GNG5 GNG12 GNG12 ADCY2 ADCY2 GNG11 GNG11 PPP3CA PPP3CA PLA2G4F PLA2G4F SHANK1 SHANK1 PLCB2 PLCB2 GNAI3 GNAI3 PLA2G4E PLA2G4E MAPK3 MAPK3 GNB2 GNB2 GNG8 GNG8 GNGT1 GNGT1 PRKCB PRKCB LOC111182367 LOC111182367 GRIN2C GRIN2C PRKCA PRKCA GRK2 GRK2 GRIA1 GRIA1 GRM3 GRM3 LOC111182370 LOC111182370 PPP3CB PPP3CB PLCB3 PLCB3 GNG13 GNG13 ADCY1 ADCY1 SHANK2 SHANK2 GNG3 GNG3 PLD2 PLD2 DLG4 DLG4 PLA2G4A PLA2G4A HOMER1 HOMER1 GRM5 GRM5 SHANK3 SHANK3 ADCY9 ADCY9 SLC1A3 SLC1A3 PPP3R1 PPP3R1 GNAS GNAS GRIN3A GRIN3A PPP3R2 PPP3R2 GNB1 GNB1 SLC17A8 SLC17A8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
MAPK1Mitogen-activated protein kinase. (380 aa)
DLGAP1Disks large-associated protein 1 isoform X1. (988 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
GRIK2Glutamate receptor ionotropic, kainate 2 isoform X2. (908 aa)
ADCY4Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1237 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
GRM1Metabotropic glutamate receptor 1. (1195 aa)
GNG14LOW QUALITY PROTEIN: uncharacterized LOC105372280 homolog. (101 aa)
HOMER2Homer protein homolog 2 isoform X1. (343 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (351 aa)
GRIK4Glutamate receptor ionotropic, kainate 4 isoform X1. (957 aa)
GRIA4Glutamate receptor 4 isoform X1. (902 aa)
HOMER3Homer protein homolog 3. (360 aa)
GLULGlutamine synthetase. (381 aa)
SLC1A6Amino acid transporter. (564 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa)
GRM6Metabotropic glutamate receptor 6. (870 aa)
GRIA3Glutamate receptor 3 isoform X1. (888 aa)
GRM7Metabotropic glutamate receptor 7. (769 aa)
LOC111171236Metabotropic glutamate receptor 7-like. (192 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform X1. (686 aa)
PPP3CCSerine/threonine-protein phosphatase. (522 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1262 aa)
GRIN3BGlutamate receptor ionotropic, NMDA 3B isoform X5; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1034 aa)
GRIK1Glutamate receptor ionotropic, kainate 1 isoform X4. (920 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
SLC38A2Sodium-coupled neutral amino acid transporter 2 isoform X1. (506 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
PLD1Phospholipase. (1151 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4 isoform X1. (340 aa)
GLS2Glutaminase liver isoform, mitochondrial isoform X1. (602 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
SLC38A1Sodium-coupled neutral amino acid transporter 1 isoform X1. (487 aa)
ADCY3Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1150 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
SLC38A3Sodium-coupled neutral amino acid transporter 3 isoform X1. (531 aa)
SLC1A1Amino acid transporter. (524 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GRM2Metabotropic glutamate receptor 2. (872 aa)
SLC1A7Amino acid transporter. (574 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2255 aa)
GRIK3Glutamate receptor ionotropic, kainate 3 isoform X1. (963 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (359 aa)
LOC111176690Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform X1. (340 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1499 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5 isoform X1. (414 aa)
LOC111177332Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
SLC1A2Amino acid transporter. (574 aa)
SLC17A6Vesicular glutamate transporter 2. (582 aa)
SLC17A7Vesicular glutamate transporter 1 isoform X1. (560 aa)
GRIN2DLOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D. (1334 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2671 aa)
GRM4Metabotropic glutamate receptor 4 isoform X1. (957 aa)
GRIK5Glutamate receptor ionotropic, kainate 5 isoform X1. (981 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
PLA2G4FPhospholipase A2. (849 aa)
SHANK1SH3 and multiple ankyrin repeat domains protein 1 isoform X1. (2170 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PLA2G4EPhospholipase A2. (868 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2. (340 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
PRKCBProtein kinase C. (689 aa)
LOC111182367Metabotropic glutamate receptor 8-like. (468 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C isoform X1. (1265 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
GRM3LOW QUALITY PROTEIN: metabotropic glutamate receptor 3. (879 aa)
LOC111182370Metabotropic glutamate receptor 8. (407 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
ADCY1Adenylate cyclase type 1. (907 aa)
SHANK2SH3 and multiple ankyrin repeat domains protein 2 isoform X1. (1901 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLD2Phospholipase. (933 aa)
DLG4Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (752 aa)
PLA2G4APhospholipase A2. (749 aa)
HOMER1Homer protein homolog 1 isoform X1. (354 aa)
GRM5Metabotropic glutamate receptor 5 isoform X1. (1208 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3 isoform X1. (1733 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
SLC1A3Amino acid transporter. (542 aa)
PPP3R1Calcineurin subunit B type 1. (170 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1023 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (231 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
SLC17A8Vesicular glutamate transporter 3. (589 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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