STRINGSTRING
MAPK1 MAPK1 GNAZ GNAZ PLCB1 PLCB1 GNAI1 GNAI1 PLCB4 PLCB4 MAP2K2 MAP2K2 GNA11 GNA11 GNAO1 GNAO1 GRM1 GRM1 ARAF ARAF LYN LYN GUCY1A2 GUCY1A2 CACNA1A CACNA1A PPP2R1B PPP2R1B GRIA3 GRIA3 HRAS HRAS RAF1 RAF1 GNA12 GNA12 PPP2CB PPP2CB ITPR1 ITPR1 GNAI2 GNAI2 PRKG1 PRKG1 KRAS KRAS ITPR2 ITPR2 GNAQ GNAQ BRAF BRAF GUCY1A3 GUCY1A3 GRID2 GRID2 MAP2K1 MAP2K1 ITPR3 ITPR3 RYR1 RYR1 GUCY1B3 GUCY1B3 PLA2G4F PLA2G4F PPP2R1A PPP2R1A PLCB2 PLCB2 NRAS NRAS GNAI3 GNAI3 PLA2G4E PLA2G4E CRHR1 CRHR1 MAPK3 MAPK3 PPP1R17 PPP1R17 GNA13 GNA13 PRKCB PRKCB PPP2CA PPP2CA PRKCA PRKCA GRIA1 GRIA1 PLCB3 PLCB3 PLA2G4A PLA2G4A IGF1R IGF1R PRKG2 PRKG2 GNAS GNAS IGF1 IGF1 NOS1 NOS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK1Mitogen-activated protein kinase. (380 aa)
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha isoform X1. (355 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa)
GRM1Metabotropic glutamate receptor 1. (1195 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (645 aa)
LYNTyrosine-protein kinase. (518 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (726 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa)
GRIA3Glutamate receptor 3 isoform X1. (888 aa)
HRASGTPase HRas isoform X1. (189 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12 isoform X2. (279 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
KRASGTPase KRas. (188 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (359 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X1. (762 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (691 aa)
GRID2Glutamate receptor ionotropic, delta-2 isoform X1. (1007 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2671 aa)
RYR1LOW QUALITY PROTEIN: ryanodine receptor 1. (5030 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
PLA2G4FPhospholipase A2. (849 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
NRASGTPase NRas. (189 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PLA2G4EPhospholipase A2. (868 aa)
CRHR1Corticotropin-releasing factor receptor 1 isoform X1; Belongs to the G-protein coupled receptor 2 family. (475 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (152 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13. (377 aa)
PRKCBProtein kinase C. (689 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PLA2G4APhospholipase A2. (749 aa)
IGF1RTyrosine-protein kinase receptor. (1368 aa)
PRKG2cGMP-dependent protein kinase. (792 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1023 aa)
IGF1Insulin-like growth factor I isoform X1. (186 aa)
NOS1Nitric oxide synthase, brain isoform X1. (1461 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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