STRINGSTRING
ADIPOQ ADIPOQ COX1 COX1 COX3 COX3 CYTB CYTB LOC111162798 LOC111162798 NDUFV2 NDUFV2 LOC111162930 LOC111162930 CDC42 CDC42 NDUFB6 NDUFB6 NDUFV3 NDUFV3 XBP1 XBP1 LOC111164113 LOC111164113 NDUFB9 NDUFB9 LOC111162636 LOC111162636 INSR INSR NDUFC1 NDUFC1 LOC111166133 LOC111166133 MLX MLX LOC111165123 LOC111165123 NDUFA7 NDUFA7 NDUFB7 NDUFB7 PIK3R2 PIK3R2 SDHC SDHC NDUFB11 NDUFB11 SDHD SDHD MAPK10 MAPK10 NDUFA11 NDUFA11 MAP3K5 MAP3K5 PKLR PKLR NDUFA12 NDUFA12 NDUFB4 NDUFB4 NDUFA13 NDUFA13 SREBF1 SREBF1 NDUFS2 NDUFS2 IL6R IL6R GSK3B GSK3B FASLG FASLG MAPK9 MAPK9 ADIPOR1 ADIPOR1 MAPK8 MAPK8 IRS1 IRS1 LOC111172152 LOC111172152 LOC111170285 LOC111170285 CASP8 CASP8 NDUFS7 NDUFS7 LOC111172449 LOC111172449 FAS FAS EIF2S1 EIF2S1 NDUFB3 NDUFB3 NDUFS1 NDUFS1 LOC111172029 LOC111172029 PRKAG3 PRKAG3 LOC111173600 LOC111173600 LOC111173965 LOC111173965 PIK3CA PIK3CA NDUFA4L2 NDUFA4L2 PRKAG1 PRKAG1 NDUFB8 NDUFB8 CASP3 CASP3 LOC111171524 LOC111171524 IKBKB IKBKB DDIT3 DDIT3 NDUFA10 NDUFA10 LOC111174575 LOC111174575 CASP7 CASP7 LOC111174833 LOC111174833 LOC111174428 LOC111174428 LOC111175766 LOC111175766 LOC111172911 LOC111172911 NDUFS5 NDUFS5 PIK3R3 PIK3R3 JUN JUN AKT1 AKT1 IRS2 IRS2 NDUFB5 NDUFB5 LOC111175937 LOC111175937 LOC111174031 LOC111174031 LOC111174197 LOC111174197 NDUFA9 NDUFA9 FOS FOS PRKAG2 PRKAG2 PRKAA2 PRKAA2 AKT3 AKT3 LOC111175930 LOC111175930 NDUFA8 NDUFA8 LOC111177953 LOC111177953 TRAF2 TRAF2 RXRA RXRA NDUFB2 NDUFB2 ADIPOR2 ADIPOR2 SDHA SDHA LOC111178277 LOC111178277 LOC111177826 LOC111177826 LEPR LEPR BID BID TNFRSF1A TNFRSF1A PIK3CB PIK3CB LOC111179428 LOC111179428 NDUFS6 NDUFS6 LOC111180406 LOC111180406 NDUFA5 NDUFA5 NDUFA3 NDUFA3 NFKB1 NFKB1 LOC111181212 LOC111181212 LOC111181221 LOC111181221 LOC111180389 LOC111180389 TGFB1 TGFB1 CEBPA CEBPA BAX BAX NDUFA4 NDUFA4 GSK3A GSK3A LOC111181225 LOC111181225 PRKAB2 PRKAB2 NDUFAB1 NDUFAB1 LOC111180543 LOC111180543 ERN1 ERN1 AKT2 AKT2 LOC111180964 LOC111180964 SOCS3 SOCS3 NDUFV1 NDUFV1 LOC111183826 LOC111183826 RAC1 RAC1 LOC111183230 LOC111183230 LOC111182267 LOC111182267 MLXIPL MLXIPL NDUFS8 NDUFS8 LOC111182105 LOC111182105 LOC111182430 LOC111182430 NDUFA2 NDUFA2 RELA RELA NR1H3 NR1H3 INS INS MAP3K11 MAP3K11 NDUFS3 NDUFS3 ITCH ITCH LOC111184329 LOC111184329 ATF4 ATF4 PPARA PPARA LOC111184910 LOC111184910 NDUFA6 NDUFA6 NDUFB10 NDUFB10 EIF2AK3 EIF2AK3 BCL2L11 BCL2L11 IL1A IL1A MLXIP MLXIP PIK3R1 PIK3R1 PRKAA1 PRKAA1 LOC111187511 LOC111187511 CXCL8 CXCL8 NDUFS4 NDUFS4 PRKAB1 PRKAB1 SDHB SDHB PIK3CD PIK3CD CO2 CO2 Ob Ob TNF TNF IL1B IL1B IL6 IL6
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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textmining
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ADIPOQC1Q and collagen domain containing adiponectin. (242 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (516 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
LOC111162798Cytochrome b-c1 complex subunit 9. (64 aa)
NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial isoform X1. (249 aa)
LOC111162930Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa)
CDC42Cell division control protein 42 homolog isoform X2. (191 aa)
NDUFB6NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 isoform X1. (128 aa)
NDUFV3NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1. (477 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
LOC111164113NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1. (58 aa)
NDUFB9NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9; Belongs to the complex I LYR family. (179 aa)
LOC111162636Cytochrome c oxidase subunit 6A, mitochondrial. (108 aa)
INSRTyrosine-protein kinase receptor. (1392 aa)
NDUFC1NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa)
LOC111166133Cytochrome b-c1 complex subunit 10. (56 aa)
MLXMax-like protein X isoform X1. (298 aa)
LOC111165123Cytochrome c1, heme protein, mitochondrial. (326 aa)
NDUFA7NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa)
NDUFB7NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. (134 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
SDHCSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (169 aa)
NDUFB11NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. (154 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
NDUFA11NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. (141 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1366 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
NDUFA12NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa)
NDUFB4NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa)
NDUFA13LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. (164 aa)
SREBF1Sterol regulatory element-binding protein 1 isoform X1. (1213 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (463 aa)
IL6RInterleukin-6 receptor subunit alpha isoform X1. (465 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
FASLGTumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ADIPOR1Adiponectin receptor protein 1. (375 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
IRS1Insulin receptor substrate 1. (1248 aa)
LOC111172152Cytochrome P450 2E1 isoform X1; Belongs to the cytochrome P450 family. (495 aa)
LOC111170285Cytochrome c oxidase subunit 8B, mitochondrial-like. (70 aa)
CASP8Caspase-8; Belongs to the peptidase C14A family. (486 aa)
NDUFS7NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1; Belongs to the complex I 20 kDa subunit family. (216 aa)
LOC111172449LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial-like. (258 aa)
FASTumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
NDUFB3NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (98 aa)
NDUFS1NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (727 aa)
LOC111172029Cytochrome c oxidase subunit 8C, mitochondrial. (67 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3. (464 aa)
LOC111173600Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa)
LOC111173965Cytochrome c oxidase subunit 6C-like. (75 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
NDUFA4L2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (87 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (330 aa)
NDUFB8NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial isoform X1. (219 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa)
LOC111171524Cytochrome c oxidase subunit 7B2, mitochondrial. (81 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
NDUFA10NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (355 aa)
LOC111174575Cytochrome c-like. (69 aa)
CASP7Caspase-7; Belongs to the peptidase C14A family. (301 aa)
LOC111174833Cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform X1. (114 aa)
LOC111174428Cytochrome b-c1 complex subunit 1, mitochondrial isoform X5. (500 aa)
LOC111175766Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (90 aa)
LOC111172911Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
NDUFS5NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (104 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (343 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IRS2Insulin receptor substrate 2. (1347 aa)
NDUFB5NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1. (189 aa)
LOC111175937NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. (129 aa)
LOC111174031Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC111174197Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
NDUFA9NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial. (377 aa)
FOSProto-oncogene c-Fos. (380 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X1. (566 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
AKT3Non-specific serine/threonine protein kinase. (541 aa)
LOC111175930Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
NDUFA8NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform X1. (206 aa)
LOC111177953Cytochrome c oxidase subunit 6C. (75 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
RXRARetinoic acid receptor RXR-alpha isoform X1. (495 aa)
NDUFB2NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (102 aa)
ADIPOR2Adiponectin receptor protein 2 isoform X1. (386 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
LOC111178277Cytochrome c oxidase subunit 7B, mitochondrial. (80 aa)
LOC111177826Cytochrome c oxidase subunit 5A, mitochondrial isoform X1. (199 aa)
LEPRLeptin receptor isoform X1. (917 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (445 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
LOC111179428Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (169 aa)
NDUFS6NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (124 aa)
LOC111180406Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (111 aa)
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa)
NDUFA3NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. (120 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa)
LOC111181212Cytochrome c oxidase subunit 7A1, mitochondrial. (153 aa)
LOC111181221NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial-like. (105 aa)
LOC111180389Cytochrome c oxidase subunit 6C. (75 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
CEBPACCAAT/enhancer-binding protein alpha. (355 aa)
BAXApoptosis regulator BAX isoform X2. (223 aa)
NDUFA4Cytochrome c oxidase subunit NDUFA4. (82 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
LOC111181225Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa)
PRKAB25'-AMP-activated protein kinase subunit beta-2 isoform X2. (272 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa)
LOC111180543Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC111180964Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
SOCS3Suppressor of cytokine signaling 3. (237 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (472 aa)
LOC111183826Cytochrome c oxidase subunit 8A, mitochondrial. (69 aa)
RAC1Ras-related C3 botulinum toxin substrate 1. (192 aa)
LOC111183230Cytochrome c oxidase subunit 7A2, mitochondrial. (83 aa)
LOC111182267Cytochrome b-c1 complex subunit 2, mitochondrial. (236 aa)
MLXIPLCarbohydrate-responsive element-binding protein isoform X1. (929 aa)
NDUFS8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1. (212 aa)
LOC111182105Cytochrome c oxidase subunit 6A, mitochondrial. (97 aa)
LOC111182430Cytochrome b-c1 complex subunit 8. (82 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
RELATranscription factor p65 isoform X1. (562 aa)
NR1H3Oxysterols receptor LXR-alpha isoform X1. (447 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (858 aa)
NDUFS3NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (270 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
LOC111184329Cytochrome c oxidase subunit 4 isoform 2, mitochondrial. (171 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X1. (350 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
LOC111184910NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (120 aa)
NDUFA6NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (127 aa)
NDUFB10NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. (176 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1155 aa)
BCL2L11Bcl-2-like protein 11 isoform X1. (288 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
MLXIPMLX-interacting protein isoform X1. (939 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
LOC111187511Cytochrome c oxidase subunit 5B, mitochondrial. (129 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
CO2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
ObLeptin isoform X1. (167 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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