STRINGSTRING
GRIN2A GRIN2A GTF2B GTF2B XBP1 XBP1 RELN RELN PSMB5 PSMB5 PSMC2 PSMC2 AFG3L2 AFG3L2 PSMA1 PSMA1 MYOD1 MYOD1 PLCB1 PLCB1 SLC25A31 SLC25A31 RB1CC1 RB1CC1 TBPL1 TBPL1 PLCB4 PLCB4 GRM1 GRM1 PSMD3 PSMD3 PIK3R2 PIK3R2 PSMB3 PSMB3 SLC1A6 SLC1A6 PSMB1 PSMB1 NRBF2 NRBF2 CACNA1A CACNA1A MAPK10 MAPK10 PIK3R4 PIK3R4 MAP3K5 MAP3K5 BECN1 BECN1 SLC25A6 SLC25A6 SLC25A5 SLC25A5 PIK3C3 PIK3C3 ULK2 ULK2 GRIA3 GRIA3 PSMD13 PSMD13 PSMB4 PSMB4 WIPI2 WIPI2 MAPK9 MAPK9 LOC111170864 LOC111170864 TBP TBP MAPK8 MAPK8 GRIN3B GRIN3B TWNK TWNK PSMD4 PSMD4 PSMD1 PSMD1 OPA1 OPA1 PSMD14 PSMD14 PSMC6 PSMC6 PSMA6 PSMA6 PSMA3 PSMA3 PIK3CA PIK3CA PSMD2 PSMD2 SLC25A4 SLC25A4 ITPR1 ITPR1 PSMD6 PSMD6 SP1 SP1 LOC111174575 LOC111174575 PUM2 PUM2 VDAC3 VDAC3 VLDLR VLDLR LOC111172911 LOC111172911 DAB1 DAB1 OMA1 OMA1 ATG14 ATG14 PIK3R3 PIK3R3 PSMC1 PSMC1 LOC111175110 LOC111175110 AKT1 AKT1 FGF14 FGF14 ATG2B ATG2B ATXN3 ATXN3 PSMB2 PSMB2 ATG101 ATG101 ITPR2 ITPR2 LOC111174031 LOC111174031 LOC111174197 LOC111174197 PUM1 PUM1 GNAQ GNAQ AKT3 AKT3 LOC111175930 LOC111175930 RORA RORA TRAF2 TRAF2 BECN2 BECN2 GRIN2B GRIN2B PSMB7 PSMB7 NFYA NFYA PSMD7 PSMD7 GRIN1 GRIN1 PSMA5 PSMA5 PIK3CB PIK3CB PSMA4 PSMA4 GRIN2D GRIN2D ITPR3 ITPR3 PSMC4 PSMC4 RYR1 RYR1 KCND3 KCND3 ATXN1L ATXN1L KCNC3 KCNC3 PSMD8 PSMD8 SEM1 SEM1 LOC111179377 LOC111179377 LOC111179676 LOC111179676 PLCB2 PLCB2 PSMA8 PSMA8 LOC111180543 LOC111180543 ERN1 ERN1 AKT2 AKT2 PRKCB PRKCB PSMC5 PSMC5 ATXN1 ATXN1 GRIN2C GRIN2C WIPI1 WIPI1 PRKCA PRKCA PPIF PPIF KAT5 KAT5 GRIA1 GRIA1 ATXN2L ATXN2L AMBRA1 AMBRA1 SPTBN2 SPTBN2 ATP2A1 ATP2A1 PLCB3 PLCB3 PDYN PDYN VDAC1 VDAC1 PSMC3 PSMC3 PSMD12 PSMD12 RBPJL RBPJL MCU MCU NOP56 NOP56 VDAC2 VDAC2 ATG2A ATG2A ATG13 ATG13 PSMA2 PSMA2 ATP2A3 ATP2A3 ATXN10 ATXN10 ULK1 ULK1 PSMD11 PSMD11 ADRM1 ADRM1 ATXN2 ATXN2 PSMB6 PSMB6 PIK3R1 PIK3R1 TRPC3 TRPC3 MTOR MTOR PSMA7 PSMA7 PSMD9 PSMD9 ATP2A2 ATP2A2 GRIN3A GRIN3A PIK3CD PIK3CD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
GTF2BTranscription initiation factor IIB. (316 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
RELNReelin isoform X1. (3460 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
AFG3L2AFG3-like protein 2 isoform X1. (805 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
SLC25A31ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1589 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
GRM1Metabotropic glutamate receptor 1. (1195 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa)
PSMB3Proteasome subunit beta. (205 aa)
SLC1A6Amino acid transporter. (564 aa)
PSMB1Proteasome subunit beta. (241 aa)
NRBF2Nuclear receptor-binding factor 2 isoform X1. (288 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2501 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
MAP3K5Mitogen-activated protein kinase kinase kinase 5 isoform X1. (1366 aa)
BECN1Beclin-1 isoform X5. (471 aa)
SLC25A6ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
SLC25A5ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
ULK2Serine/threonine-protein kinase ULK2 isoform X1. (1045 aa)
GRIA3Glutamate receptor 3 isoform X1. (888 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
WIPI2WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (436 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
LOC111170864Recombining binding protein suppressor of hairless isoform X1. (500 aa)
TBPTATA-box-binding protein. (319 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
GRIN3BGlutamate receptor ionotropic, NMDA 3B isoform X5; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1034 aa)
TWNKTwinkle protein, mitochondrial isoform X1. (684 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa)
OPA1Dynamin-like 120 kDa protein, mitochondrial isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SLC25A4ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2749 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa)
SP1Transcription factor Sp1. (786 aa)
LOC111174575Cytochrome c-like. (69 aa)
PUM2Pumilio homolog 2 isoform X1. (1065 aa)
VDAC3Voltage-dependent anion-selective channel protein 3. (283 aa)
VLDLRVery low-density lipoprotein receptor isoform X1. (873 aa)
LOC111172911Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
DAB1Disabled homolog 1 isoform X1. (551 aa)
OMA1Metalloendopeptidase OMA1, mitochondrial isoform X1. (543 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa)
PSMC126S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
LOC111175110Nuclear receptor-binding factor 2-like. (226 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
ATG2BAutophagy-related protein 2 homolog B isoform X1. (2089 aa)
ATXN3Ataxin-3 isoform X1. (348 aa)
PSMB2Proteasome subunit beta. (201 aa)
ATG101Autophagy-related protein 101. (218 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2 isoform X1. (2701 aa)
LOC111174031Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC111174197Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa)
PUM1Pumilio homolog 1 isoform X1. (1193 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (359 aa)
AKT3Non-specific serine/threonine protein kinase. (541 aa)
LOC111175930Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
RORANuclear receptor ROR-alpha isoform X1. (523 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
BECN2Beclin-2. (432 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1499 aa)
PSMB7Proteasome subunit beta. (277 aa)
NFYANuclear transcription factor Y subunit alpha isoform X1. (347 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (322 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
GRIN2DLOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D. (1334 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3 isoform X1. (2671 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa)
RYR1LOW QUALITY PROTEIN: ryanodine receptor 1. (5030 aa)
KCND3Potassium voltage-gated channel subfamily D member 3 isoform X1; Belongs to the potassium channel family. (655 aa)
ATXN1LAtaxin-1-like. (688 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3 isoform X1; Belongs to the potassium channel family. (777 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
SEM126S proteasome complex subunit SEM1 isoform X1. (100 aa)
LOC111179377LOW QUALITY PROTEIN: AFG3-like protein 1; Belongs to the AAA ATPase family. (686 aa)
LOC111179676Protein BEAN1. (260 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
PSMA8Proteasome subunit alpha type. (269 aa)
LOC111180543Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1. (975 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKCBProtein kinase C. (689 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
ATXN1Ataxin-1. (807 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C isoform X1. (1265 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (462 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
PPIFPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
ATXN2LAtaxin-2-like protein isoform X6. (1097 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1295 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2397 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1006 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
PDYNproenkephalin-B. (252 aa)
VDAC1Voltage-dependent anion-selective channel protein 1. (283 aa)
PSMC326S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12. (456 aa)
RBPJLRecombining binding protein suppressor of hairless-like protein. (516 aa)
MCUCalcium uniporter protein, mitochondrial isoform X1. (371 aa)
NOP56Nucleolar protein 56. (595 aa)
VDAC2Voltage-dependent anion-selective channel protein 2. (294 aa)
ATG2AAutophagy-related protein 2 homolog A isoform X1. (1928 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (551 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa)
ATXN10Ataxin-10 isoform X1. (475 aa)
ULK1Serine/threonine-protein kinase ULK1 isoform X1. (1055 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
ADRM1Proteasomal ubiquitin receptor ADRM1. (407 aa)
ATXN2Ataxin-2 isoform X3. (1351 aa)
PSMB6Proteasome subunit beta. (239 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
TRPC3LOW QUALITY PROTEIN: short transient receptor potential channel 3; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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