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| | DYNLL1 | Dynein light chain. (89 aa) |
| | MYL12B | Myosin regulatory light chain 12B. (172 aa) |
| | CDC42 | Cell division control protein 42 homolog isoform X2. (191 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (380 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | LOC111162912 | Myosin regulatory light chain 12B. (171 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | GSDMD | gasdermin-D isoform X1. (487 aa) |
| | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (226 aa) |
| | DYNC1LI1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa) |
| | ROCK2 | Rho-associated protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1416 aa) |
| | PIK3CG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (458 aa) |
| | DNM2 | Dynamin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa) |
| | RAB5C | Ras-related protein Rab-5C. (216 aa) |
| | PKN1 | Serine/threonine-protein kinase N1 isoform X1. (950 aa) |
| | PIK3C2A | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1; Belongs to the PI3/PI4-kinase family. (1711 aa) |
| | STX10 | Syntaxin-10 isoform X1. (249 aa) |
| | TCF7L1 | Transcription factor 7-like 1 isoform X1. (601 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) |
| | RAB5A | Ras-related protein Rab-5A isoform X1. (215 aa) |
| | NLRP3 | NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1035 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) |
| | LOC111167555 | Caspase-13 isoform X1; Belongs to the peptidase C14A family. (377 aa) |
| | SNX9 | Sorting nexin. (594 aa) |
| | CASP1 | Caspase-1; Belongs to the peptidase C14A family. (404 aa) |
| | PAK3 | Non-specific serine/threonine protein kinase. (559 aa) |
| | PTPRC | Receptor-type tyrosine-protein phosphatase C isoform X1. (1258 aa) |
| | BIRC3 | Baculoviral IAP repeat-containing protein 3 isoform X1. (604 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | TAB3 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 3. (717 aa) |
| | ARF1 | ADP-ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | LOC111167795 | Rho-related GTP-binding protein RhoG-like isoform X1. (230 aa) |
| | ARPC4 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa) |
| | LOC111168369 | Baculoviral IAP repeat-containing protein 2. (620 aa) |
| | DYNLT1 | Dynein light chain Tctex-type 1 isoform X1. (113 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | DYNC2H1 | Cytoplasmic dynein 2 heavy chain 1. (4307 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | RAB7A | Ras-related protein Rab-7a. (207 aa) |
| | FLNA | filamin-A isoform X1. (2647 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) |
| | RAB9A | Ras-related protein Rab-9A. (201 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | LOC111170545 | Rho-related GTP-binding protein RhoG. (191 aa) |
| | S100A10 | Protein S100-A10; Belongs to the S-100 family. (96 aa) |
| | LEF1 | Lymphoid enhancer-binding factor 1 isoform X1. (414 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | LOC111171283 | Neuroblast differentiation-associated protein AHNAK-like. (1016 aa) |
| | ELMO2 | Engulfment and cell motility protein 2 isoform X1. (720 aa) |
| | PLEKHM1 | Pleckstrin homology domain-containing family M member 1 isoform X1. (1089 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | DYNLT3 | Dynein light chain Tctex-type 3. (116 aa) |
| | RAB9B | Ras-related protein Rab-9B. (201 aa) |
| | TLR6 | Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa) |
| | PFN3 | Profilin; Belongs to the profilin family. (137 aa) |
| | BRK1 | Protein BRICK1. (75 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | DYNC1I2 | LOW QUALITY PROTEIN: cytoplasmic dynein 1 intermediate chain 2. (612 aa) |
| | EXOC5 | Exocyst complex component 5. (708 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | RHOH | Rho-related GTP-binding protein RhoH. (191 aa) |
| | ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa) |
| | ARF6 | ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | TCF7L2 | Transcription factor 7-like 2 isoform X1. (668 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | NCKAP1L | Nck-associated protein 1-like isoform X1. (1156 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa) |
| | NCKAP1 | Nck-associated protein 1 isoform X1. (1134 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (288 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa) |
| | FLNB | filamin-B isoform X1. (2633 aa) |
| | LOC111174575 | Cytochrome c-like. (69 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | NLRC4 | NLR family CARD domain-containing protein 4 isoform X1. (1024 aa) |
| | CASP7 | Caspase-7; Belongs to the peptidase C14A family. (301 aa) |
| | TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) |
| | PFN4 | Profilin; Belongs to the profilin family. (129 aa) |
| | RAB5B | Ras-related protein Rab-5B. (215 aa) |
| | LOC111172911 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | RHOJ | Rho-related GTP-binding protein RhoJ. (236 aa) |
| | HSP90AA1 | Heat shock protein HSP 90-alpha. (733 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | KLC1 | Kinesin light chain 1 isoform X1. (670 aa) |
| | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1. (4645 aa) |
| | RHOB | Rho-related GTP-binding protein RhoB. (196 aa) |
| | LOC111174031 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC111174197 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | KPNA4 | Importin subunit alpha; Functions in nuclear protein import. (521 aa) |
| | FYCO1 | FYVE and coiled-coil domain-containing protein 1. (1461 aa) |
| | TLR5 | Toll-like receptor 5; Belongs to the Toll-like receptor family. (858 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | LOC111175930 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC111176002 | Protein AHNAK2-like. (1875 aa) |
| | M6PR | Cation-dependent mannose-6-phosphate receptor isoform X1. (316 aa) |
| | DYNC2LI1 | Cytoplasmic dynein 2 light intermediate chain 1. (351 aa) |
| | PIK3C2G | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1483 aa) |
| | TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) |
| | FBXO22 | F-box only protein 22 isoform X1. (408 aa) |
| | ABI1 | Abl interactor 1 isoform X1. (508 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | KPNA3 | Importin subunit alpha; Functions in nuclear protein import. (521 aa) |
| | TXN | Thioredoxin; Belongs to the thioredoxin family. (105 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X1. (239 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | EXOC4 | Exocyst complex component 4. (975 aa) |
| | ARHGEF26 | Rho guanine nucleotide exchange factor 26. (870 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase. (333 aa) |
| | LOC111176950 | Dynein light chain. (116 aa) |
| | FLNC | filamin-C isoform X5. (2720 aa) |
| | SNX33 | Sorting nexin. (574 aa) |
| | ARPC5L | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa) |
| | WASL | Neural Wiskott-Aldrich syndrome protein isoform X1. (510 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | PODXL | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (532 aa) |
| | ANXA2 | Annexin. (339 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | HSP90AB1 | Heat shock protein HSP 90-beta. (724 aa) |
| | NOD1 | Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (953 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | DYNC1I1 | Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa) |
| | ELMO1 | Engulfment and cell motility protein 1 isoform X1. (727 aa) |
| | KLC4 | Kinesin light chain 4 isoform X1. (616 aa) |
| | RRAS | Ras-related protein R-Ras isoform X1. (251 aa) |
| | BAX | Apoptosis regulator BAX isoform X2. (223 aa) |
| | FHOD1 | FH1/FH2 domain-containing protein 1 isoform X1. (1195 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa) |
| | DYNC1LI2 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa) |
| | MLKL | LOW QUALITY PROTEIN: mixed lineage kinase domain-like protein. (405 aa) |
| | DYNLRB2 | Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (233 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (687 aa) |
| | VPS18 | Vacuolar protein sorting-associated protein 18 homolog. (973 aa) |
| | LOC111180543 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CYTH3 | Cytohesin-3 isoform X1. (400 aa) |
| | TCF7 | Transcription factor 7 isoform X1. (415 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MYLPF | Myosin regulatory light chain 2, skeletal muscle isoform. (170 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | ARPC1A | Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa) |
| | CYTH2 | Cytohesin-2. (399 aa) |
| | KLC3 | Kinesin light chain 3. (505 aa) |
| | MYL10 | Myosin regulatory light chain 10. (147 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (929 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (796 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (368 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | VPS39 | vam6/Vps39-like protein isoform X1. (875 aa) |
| | MYO6 | Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (192 aa) |
| | ARPC1B | Actin-related protein 2/3 complex subunit 1B isoform X1. (425 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | SKP1 | S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (164 aa) |
| | KLC2 | Kinesin light chain 2 isoform X1. (656 aa) |
| | CYTH1 | Cytohesin-1 isoform X1. (410 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | LOC111182578 | ADP-ribosylation factor 2 isoform X1; Belongs to the small GTPase superfamily. Arf family. (231 aa) |
| | LOC111183871 | Neuroblast differentiation-associated protein AHNAK-like isoform X1. (165 aa) |
| | MYL9 | Myosin regulatory light polypeptide 9. (172 aa) |
| | RPS3 | 40S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | RAB7B | Ras-related protein Rab-7b isoform X1. (210 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (543 aa) |
| | PIK3C2B | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa) |
| | DYNLRB1 | Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X4; Belongs to the protein kinase superfamily. (410 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | RALA | Ras-related protein Ral-A. (206 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | RILP | Rab-interacting lysosomal protein isoform X1. (447 aa) |
| | MYL7 | Myosin regulatory light chain 2, atrial isoform isoform X1. (176 aa) |
| | ARPC5 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa) |
| | LOC111185785 | Baculoviral IAP repeat-containing protein 1 isoform X1. (1759 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (504 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (140 aa) |
| | PLEKHM2 | Pleckstrin homology domain-containing family M member 2 isoform X1. (1024 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (456 aa) |
| | LOC111185435 | Tumor necrosis factor receptor superfamily member 10A-like isoform X1. (454 aa) |
| | LOC111185436 | Tumor necrosis factor receptor superfamily member 10B-like isoform X1. (456 aa) |
| | SNX18 | Sorting nexin. (625 aa) |
| | CSE1L | Exportin-2 isoform X1. (1020 aa) |
| | VPS33A | Vacuolar protein sorting-associated protein 33A isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (612 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa) |
| | MYL2 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa) |
| | TXN2 | Thioredoxin, mitochondrial. (166 aa) |
| | CYTH4 | Cytohesin-4. (420 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | GCC2 | GRIP and coiled-coil domain-containing protein 2 isoform X1. (1680 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | HSP90B1 | Endoplasmin. (805 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
