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C1QA | Complement C1q subcomponent subunit A. (245 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (380 aa) | ||||
C1QC | Complement C1q subcomponent subunit C. (245 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) | ||||
TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (226 aa) | ||||
C1QB | Complement C1q subcomponent subunit B. (290 aa) | ||||
GNAI1 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa) | ||||
NLRP3 | NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1035 aa) | ||||
TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (707 aa) | ||||
C3 | Complement C3 isoform X1. (1695 aa) | ||||
CASP1 | Caspase-1; Belongs to the peptidase C14A family. (404 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (464 aa) | ||||
IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) | ||||
LOC111170700 | Complement C4-like isoform X1. (1740 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
C2 | Complement C2 isoform X1; Belongs to the peptidase S1 family. (751 aa) | ||||
CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa) | ||||
GNAI2 | Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa) | ||||
IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) | ||||
CFL2 | Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa) | ||||
CASP7 | Caspase-7; Belongs to the peptidase C14A family. (301 aa) | ||||
JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) | ||||
RHOA | Transforming protein RhoA. (193 aa) | ||||
C1S | Complement C1s subcomponent; Belongs to the peptidase S1 family. (695 aa) | ||||
FOS | Proto-oncogene c-Fos. (380 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) | ||||
C1R | Complement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (713 aa) | ||||
CALML4 | Calmodulin-like protein 4 isoform X1. (189 aa) | ||||
TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) | ||||
C5 | Complement C5 isoform X1. (1677 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
CALM1 | Calmodulin-1; Belongs to the calmodulin family. (149 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
IRF8 | Interferon regulatory factor 8 isoform X1. (427 aa) | ||||
ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (798 aa) | ||||
IRF3 | Interferon regulatory factor 3 isoform X1. (464 aa) | ||||
NOD1 | Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (953 aa) | ||||
NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) | ||||
PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) | ||||
GNAI3 | Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa) | ||||
IRF1 | Interferon regulatory factor. (322 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) | ||||
ITGAM | Integrin alpha-M; Belongs to the integrin alpha chain family. (872 aa) | ||||
LOC111183594 | Pulmonary surfactant-associated protein A. (283 aa) | ||||
CFL1 | Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa) | ||||
CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) | ||||
RELA | Transcription factor p65 isoform X1. (562 aa) | ||||
SERPING1 | Plasma protease C1 inhibitor; Belongs to the serpin family. (471 aa) | ||||
TICAM2 | TIR domain-containing adapter molecule 2. (235 aa) | ||||
C4BPA | C4b-binding protein alpha chain isoform X1. (616 aa) | ||||
IL10 | Interleukin-10. (178 aa) | ||||
C4BPB | C4b-binding protein beta chain isoform X1. (255 aa) | ||||
LY96 | Lymphocyte antigen 96. (160 aa) | ||||
LOC111185989 | Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (456 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) | ||||
CALML6 | Calmodulin-like protein 6 isoform X2. (227 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (366 aa) | ||||
ITGB2 | Integrin beta. (769 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa) | ||||
LOC111187648 | C-X-C motif chemokine 6-like. (113 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |