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MAPK1 | Mitogen-activated protein kinase. (380 aa) | ||||
IFNGR2 | Interferon gamma receptor 2. (364 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) | ||||
MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) | ||||
ELK1 | LOW QUALITY PROTEIN: ETS domain-containing protein Elk-1. (442 aa) | ||||
IFNGR1 | Interferon gamma receptor 1. (469 aa) | ||||
TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) | ||||
C3 | Complement C3 isoform X1. (1695 aa) | ||||
IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) | ||||
IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) | ||||
ITGA4 | Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa) | ||||
STAT1 | Signal transducer and activator of transcription. (749 aa) | ||||
LOC111170413 | Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1. (278 aa) | ||||
LOC111170450 | Cytochrome b-245 heavy chain isoform X1. (570 aa) | ||||
JAK2 | Tyrosine-protein kinase. (1132 aa) | ||||
IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) | ||||
NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) | ||||
JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) | ||||
FOS | Proto-oncogene c-Fos. (380 aa) | ||||
MARCKSL1 | MARCKS-related protein. (198 aa) | ||||
IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) | ||||
TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) | ||||
TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) | ||||
LOC111178664 | HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa) | ||||
MAPK14 | Mitogen-activated protein kinase. (360 aa) | ||||
LOC111178928 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa) | ||||
LOC111178931 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa) | ||||
TGFB3 | Transforming growth factor beta-3. (456 aa) | ||||
LOC111178043 | LOW QUALITY PROTEIN: elongation factor 1-alpha 1-like. (404 aa) | ||||
LOC111178668 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (366 aa) | ||||
LOC111179403 | Cytochrome b-245 light chain isoform X1. (202 aa) | ||||
LOC111178925 | boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa) | ||||
LOC111178929 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa) | ||||
ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (798 aa) | ||||
LOC111178666 | HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (261 aa) | ||||
NFKBIB | NF-kappa-B inhibitor beta. (353 aa) | ||||
JAK1 | Tyrosine-protein kinase. (1153 aa) | ||||
NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) | ||||
LOC111179231 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (421 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) | ||||
LOC111178927 | HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa) | ||||
NCF1 | Neutrophil cytosol factor 1 isoform X2. (405 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) | ||||
MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) | ||||
ITGAM | Integrin alpha-M; Belongs to the integrin alpha chain family. (872 aa) | ||||
PRKCB | Protein kinase C. (689 aa) | ||||
EEF1A1 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa) | ||||
IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (133 aa) | ||||
RELA | Transcription factor p65 isoform X1. (562 aa) | ||||
NCF2 | Neutrophil cytosol factor 2 isoform X1. (526 aa) | ||||
CR1 | Complement receptor type 1 isoform X1. (1062 aa) | ||||
IL10 | Interleukin-10. (178 aa) | ||||
PTGS2 | Prostaglandin G/H synthase 2. (604 aa) | ||||
TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (504 aa) | ||||
LOC111185989 | Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa) | ||||
EEF1A2 | Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa) | ||||
MAPK12 | Mitogen-activated protein kinase. (456 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) | ||||
MAPK11 | Mitogen-activated protein kinase. (366 aa) | ||||
LOC111186386 | Neutrophil cytosol factor 4-like. (250 aa) | ||||
ITGB2 | Integrin beta. (769 aa) | ||||
LOC111187847 | Neutrophil cytosol factor 4 isoform X2. (339 aa) | ||||
TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) | ||||
IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |