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| | C1QA | Complement C1q subcomponent subunit A. (245 aa) |
| | GNAL | Guanine nucleotide-binding protein G(Olf) subunit alpha isoform X2. (380 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (380 aa) |
| | LOC111163731 | C-C motif chemokine. (93 aa) |
| | C1QC | Complement C1q subcomponent subunit C. (245 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (364 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | LOC111163733 | C-C motif chemokine. (90 aa) |
| | C1QB | Complement C1q subcomponent subunit B. (290 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | GNAI1 | Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1. (354 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (469 aa) |
| | GNA11 | Guanine nucleotide-binding protein subunit alpha-11. (359 aa) |
| | GNAO1 | Guanine nucleotide-binding protein G(O) subunit alpha isoform X1. (354 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain. (171 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain. (178 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain. (197 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (707 aa) |
| | C3 | Complement C3 isoform X1. (1695 aa) |
| | GNA15 | Guanine nucleotide-binding protein subunit alpha-15 isoform X1. (374 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | CALR | Calreticulin. (417 aa) |
| | CD247 | T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (547 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | TLR6 | Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa) |
| | KNG1 | Kininogen-1 isoform X1. (627 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | GNAI2 | Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa) |
| | GNA14 | Guanine nucleotide-binding protein subunit alpha-14. (355 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | BDKRB2 | B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (359 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | TGFB3 | Transforming growth factor beta-3. (456 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa) |
| | GNAI3 | Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | ACE | Angiotensin-converting enzyme. (1310 aa) |
| | SERPINE1 | Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (545 aa) |
| | ADCY1 | Adenylate cyclase type 1. (907 aa) |
| | IL10 | Interleukin-10. (178 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X4; Belongs to the protein kinase superfamily. (410 aa) |
| | LOC111185731 | C-C motif chemokine. (99 aa) |
| | LOC111185989 | Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (456 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa) |
| | GNAS | Guanine nucleotide-binding protein G(S) subunit alpha isoforms XLas isoform X1. (1023 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells (By similarity); Belongs to the IL-2 family. (154 aa) |
