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| | MAPK1 | Mitogen-activated protein kinase. (380 aa) |
| | EEA1 | Early endosome antigen 1 isoform X1. (1453 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (364 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | CIITA | MHC class II transactivator isoform X2. (1206 aa) |
| | NOD2 | Nucleotide-binding oligomerization domain-containing protein 2 isoform X1. (1086 aa) |
| | IL10RB | Interleukin-10 receptor subunit beta isoform X1. (361 aa) |
| | ATP6V0D2 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa) |
| | LOC111163130 | Interferon alpha-1-like. (226 aa) |
| | TIRAP | Toll/interleukin-1 receptor domain-containing adapter protein. (226 aa) |
| | CD209 | CD209 antigen. (279 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (469 aa) |
| | RAB5C | Ras-related protein Rab-5C. (216 aa) |
| | RFXANK | DNA-binding protein RFXANK isoform X1. (260 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (845 aa) |
| | RAB5A | Ras-related protein Rab-5A isoform X1. (215 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (86 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (480 aa) |
| | C3 | Complement C3 isoform X1. (1695 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | LAMP2 | Lysosome-associated membrane glycoprotein 2 isoform X1. (411 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | IL10RA | Interleukin-10 receptor subunit alpha isoform X1. (579 aa) |
| | CTSS | Cathepsin S; Belongs to the peptidase C1 family. (340 aa) |
| | RFX5 | DNA-binding protein RFX5 isoform X1. (679 aa) |
| | LSP1 | Lymphocyte-specific protein 1 isoform X1. (362 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12 isoform X1. (1544 aa) |
| | CTSD | Cathepsin D; Belongs to the peptidase A1 family. (411 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | RAB7A | Ras-related protein Rab-7a. (207 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | TLR1 | Toll-like receptor 1; Belongs to the Toll-like receptor family. (796 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (518 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | IRAK2 | LOW QUALITY PROTEIN: interleukin-1 receptor-associated kinase-like 2. (621 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (522 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | LOC111170413 | Low affinity immunoglobulin gamma Fc region receptor III-like isoform X1. (278 aa) |
| | TLR6 | Toll-like receptor 6; Belongs to the Toll-like receptor family. (797 aa) |
| | LOC111171121 | Interferon alpha-1-like. (133 aa) |
| | HSPD1 | 60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa) |
| | CREB1 | Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa) |
| | ATP6AP1 | V-type proton ATPase subunit S1. (469 aa) |
| | LOC111171039 | Protegrin-2-like isoform X1. (218 aa) |
| | LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | VDR | Vitamin D3 receptor isoform X1. (503 aa) |
| | LOC111174575 | Cytochrome c-like. (69 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | TLR9 | LOW QUALITY PROTEIN: toll-like receptor 9. (1323 aa) |
| | RAB5B | Ras-related protein Rab-5B. (215 aa) |
| | LOC111172911 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PLA2R1 | Secretory phospholipase A2 receptor. (1389 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CAMP | Cathelicidin antimicrobial peptide isoform X1. (162 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | NFYC | Nuclear transcription factor Y subunit gamma isoform X1. (439 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | LOC111176754 | C-type lectin domain family 7 member A-like isoform X1. (244 aa) |
| | LOC111174031 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC111174197 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | LAMP1 | Lysosome-associated membrane glycoprotein 1. (411 aa) |
| | ATP6V0B | V-type proton ATPase 21 kDa proteolipid subunit isoform X1; Belongs to the V-ATPase proteolipid subunit family. (233 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | LOC111175930 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CALML4 | Calmodulin-like protein 4 isoform X1. (189 aa) |
| | TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | MRC1 | Macrophage mannose receptor 1. (1455 aa) |
| | LOC111176721 | C-type lectin domain family 4 member E-like. (212 aa) |
| | LOC111178664 | HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | CARD9 | Caspase recruitment domain-containing protein 9 isoform X1. (539 aa) |
| | CALM1 | Calmodulin-1; Belongs to the calmodulin family. (149 aa) |
| | LOC111178928 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa) |
| | LOC111178931 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa) |
| | TGFB3 | Transforming growth factor beta-3. (456 aa) |
| | LOC111178668 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | NFYA | Nuclear transcription factor Y subunit alpha isoform X1. (347 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | LOC111178925 | boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa) |
| | LOC111178929 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa) |
| | LOC111178666 | HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (261 aa) |
| | CEBPG | CCAAT/enhancer-binding protein gamma. (149 aa) |
| | BCL10 | B-cell lymphoma/leukemia 10. (233 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa) |
| | BAX | Apoptosis regulator BAX isoform X2. (223 aa) |
| | LOC111178927 | HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa) |
| | ATP6V0D1 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (233 aa) |
| | MALT1 | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (850 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | LOC111180543 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC111182106 | Integrin alpha-X-like isoform X1; Belongs to the integrin alpha chain family. (1210 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | SPHK2 | Sphingosine kinase 2 isoform X1. (655 aa) |
| | ITGAM | Integrin alpha-M; Belongs to the integrin alpha chain family. (872 aa) |
| | HSPA9 | Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa) |
| | CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1. (610 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (840 aa) |
| | SPHK1 | Sphingosine kinase 1 isoform X2. (484 aa) |
| | MRC2 | C-type mannose receptor 2. (1446 aa) |
| | CD74 | HLA class II histocompatibility antigen gamma chain isoform X1. (278 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (525 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (489 aa) |
| | SRC | Tyrosine-protein kinase. (562 aa) |
| | CR1 | Complement receptor type 1 isoform X1. (1062 aa) |
| | IL10 | Interleukin-10. (178 aa) |
| | TCIRG1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (873 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | KSR1 | Kinase suppressor of Ras 1 isoform X1. (905 aa) |
| | LBP | Lipopolysaccharide-binding protein isoform X1. (537 aa) |
| | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1. (542 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2442 aa) |
| | CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1. (542 aa) |
| | LOC111185989 | Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (452 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (456 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (345 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (867 aa) |
| | CALML6 | Calmodulin-like protein 6 isoform X2. (227 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | ITGB2 | Integrin beta. (769 aa) |
| | PPP3R1 | Calcineurin subunit B type 1. (170 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | NFYB | Nuclear transcription factor Y subunit beta isoform X1. (227 aa) |
| | PPP3R2 | LOW QUALITY PROTEIN: calcineurin subunit B type 2. (231 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
