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| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (380 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1 isoform X1. (561 aa) |
| | E2F2 | Transcription factor E2F2 isoform X1. (437 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (594 aa) |
| | IRF9 | LOW QUALITY PROTEIN: interferon regulatory factor 9. (479 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | LOC111163130 | Interferon alpha-1-like. (226 aa) |
| | LOC111163861 | LOW QUALITY PROTEIN: interferon-induced GTP-binding protein Mx1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (518 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa) |
| | TYK2 | Tyrosine-protein kinase. (1188 aa) |
| | LOC111166275 | Proteasome activator complex subunit 3-like. (165 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform X1. (645 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (707 aa) |
| | LDLR | Low-density lipoprotein receptor. (857 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (601 aa) |
| | CLDN25 | LOW QUALITY PROTEIN: putative claudin-25. (230 aa) |
| | LOC111166421 | Proteasome activator complex subunit 3. (254 aa) |
| | CTNNB1 | Catenin beta-1. (781 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (473 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | CFLAR | CASP8 and FADD-like apoptosis regulator isoform X1; Belongs to the peptidase C14A family. (547 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (453 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | LOC111171121 | Interferon alpha-1-like. (133 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (293 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | STAT2 | Signal transducer and activator of transcription. (911 aa) |
| | LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) |
| | SOS2 | Son of sevenless homolog 2 isoform X1. (1332 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | LOC111174575 | Cytochrome c-like. (69 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | SOS1 | Son of sevenless homolog 1 isoform X1. (1333 aa) |
| | LOC111173597 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa) |
| | LOC111175442 | 14-3-3 protein gamma-like; Belongs to the 14-3-3 family. (153 aa) |
| | LOC111172911 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (539 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa) |
| | KRAS | GTPase KRas. (188 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa) |
| | LOC111174031 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC111174197 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | LOC111175930 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | RXRA | Retinoic acid receptor RXR-alpha isoform X1. (495 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (254 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X1. (239 aa) |
| | BRAF | Serine/threonine-protein kinase B-raf isoform X1. (762 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | LOC111179149 | 14-3-3 protein gamma-like; Belongs to the 14-3-3 family. (246 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PIAS1 | E3 SUMO-protein ligase PIAS1 isoform X1. (651 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (464 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | BAX | Apoptosis regulator BAX isoform X2. (223 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (687 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa) |
| | NRAS | GTPase NRas. (189 aa) |
| | LOC111180543 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EIF2AK1 | Eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1. (623 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | EIF2AK4 | eIF-2-alpha kinase GCN2. (1530 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | CLDN3 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | E2F3 | LOW QUALITY PROTEIN: transcription factor E2F3. (461 aa) |
| | CD81 | Tetraspanin. (236 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (237 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (217 aa) |
| | YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | NR1H3 | Oxysterols receptor LXR-alpha isoform X1. (447 aa) |
| | RNASEL | 2-5A-dependent ribonuclease isoform X1. (665 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (545 aa) |
| | BAD | Bcl2-associated agonist of cell death. (168 aa) |
| | YWHAB | 14-3-3 protein beta/alpha isoform X1; Belongs to the 14-3-3 family. (246 aa) |
| | E2F1 | Transcription factor E2F1. (437 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein isoform X1. (581 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1209 aa) |
| | PPARA | Peroxisome proliferator-activated receptor alpha. (468 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (807 aa) |
| | CLDN9 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (452 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1155 aa) |
| | CXCL10 | C-X-C motif chemokine. (103 aa) |
| | YWHAE | 14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | SCARB1 | Scavenger receptor class B member 1 isoform X1; Belongs to the CD36 family. (511 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (387 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
