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| | MAPK1 | Mitogen-activated protein kinase. (380 aa) |
| | TRIM25 | E3 ubiquitin/ISG15 ligase TRIM25 isoform X1. (634 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1 isoform X1. (561 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (594 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (364 aa) |
| | TMPRSS2 | Transmembrane protease serine 2 isoform X4; Belongs to the peptidase S1 family. (528 aa) |
| | IRF9 | LOW QUALITY PROTEIN: interferon regulatory factor 9. (479 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | CIITA | MHC class II transactivator isoform X2. (1206 aa) |
| | CCL5 | C-C motif chemokine. (91 aa) |
| | LOC111163130 | Interferon alpha-1-like. (226 aa) |
| | KPNA5 | Importin subunit alpha; Functions in nuclear protein import. (536 aa) |
| | PABPN1 | Polyadenylate-binding protein 2. (306 aa) |
| | SLC25A31 | ADP/ATP translocase 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) |
| | LOC111163861 | LOW QUALITY PROTEIN: interferon-induced GTP-binding protein Mx1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (518 aa) |
| | RAB11B | Ras-related protein Rab-11B. (218 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2 isoform X1; Belongs to the protein kinase superfamily. (400 aa) |
| | TYK2 | Tyrosine-protein kinase. (1188 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (536 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (469 aa) |
| | NXT2 | NTF2-related export protein 2 isoform X1. (142 aa) |
| | CALCOCO2 | Calcium-binding and coiled-coil domain-containing protein 2. (448 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | NLRP3 | NACHT, LRR and PYD domains-containing protein 3 isoform X1. (1035 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (707 aa) |
| | FDPS | Farnesyl pyrophosphate synthase isoform X1; Belongs to the FPP/GGPP synthase family. (425 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | TLR7 | Toll-like receptor 7 isoform X1. (1086 aa) |
| | NLRX1 | NLR family member X1 isoform X1. (973 aa) |
| | CASP1 | Caspase-1; Belongs to the peptidase C14A family. (404 aa) |
| | DNAJB1 | dnaJ homolog subfamily B member 1. (340 aa) |
| | PLG | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa) |
| | SLC25A6 | ADP/ATP translocase 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | SLC25A5 | ADP/ATP translocase 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | TMPRSS4 | LOW QUALITY PROTEIN: transmembrane protease serine 4; Belongs to the peptidase S1 family. (422 aa) |
| | ADAR | Double-stranded RNA-specific adenosine deaminase isoform X1. (1174 aa) |
| | FASLG | Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (473 aa) |
| | ACTB | Actin, cytoplasmic 1. (375 aa) |
| | NUP98 | Nuclear pore complex protein Nup98-Nup96 isoform X1. (1842 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (329 aa) |
| | RAF1 | RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa) |
| | IFIH1 | Interferon-induced helicase C domain-containing protein 1. (1023 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | LOC111171121 | Interferon alpha-1-like. (133 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | STAT2 | Signal transducer and activator of transcription. (911 aa) |
| | LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa) |
| | SLC25A4 | ADP/ATP translocase 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (905 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (288 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa) |
| | IL33 | Interleukin-33 isoform X1. (271 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | LOC111174575 | Cytochrome c-like. (69 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | LOC111172911 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (539 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | DNAJC3 | dnaJ homolog subfamily C member 3. (504 aa) |
| | LOC111174031 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC111174197 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | KPNA6 | Importin subunit alpha; Functions in nuclear protein import. (577 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (222 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | LOC111175930 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TLR4 | Toll-like receptor 4 isoform X1; Belongs to the Toll-like receptor family. (841 aa) |
| | LOC111178664 | HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X1. (239 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | LOC111178928 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa) |
| | LOC111178931 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa) |
| | PML | Protein PML isoform X1. (861 aa) |
| | LOC111178668 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (445 aa) |
| | LOC111178925 | boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa) |
| | LOC111178929 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | RAB11A | Ras-related protein Rab-11A isoform X1. (218 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | LOC111178666 | HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (261 aa) |
| | NFKBIB | NF-kappa-B inhibitor beta. (353 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (464 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | PABPN1L | Embryonic polyadenylate-binding protein 2 isoform X1. (277 aa) |
| | BAX | Apoptosis regulator BAX isoform X2. (223 aa) |
| | LOC111178927 | HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa) |
| | CPSF4 | Cleavage and polyadenylation specificity factor subunit 4 isoform X1. (309 aa) |
| | PYCARD | Apoptosis-associated speck-like protein containing a CARD. (195 aa) |
| | LOC111180543 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | KPNA2 | Importin subunit alpha; Functions in nuclear protein import. (529 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (382 aa) |
| | HNRNPUL1 | Heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1. (858 aa) |
| | PRKCB | Protein kinase C. (689 aa) |
| | KPNA7 | Importin subunit alpha; Functions in nuclear protein import. (563 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa) |
| | ACTG1 | Actin, cytoplasmic 2. (375 aa) |
| | SOCS3 | Suppressor of cytokine signaling 3. (237 aa) |
| | CPSF4L | Putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X2. (198 aa) |
| | NXF1 | Nuclear RNA export factor 1. (620 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1. (283 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | RNASEL | 2-5A-dependent ribonuclease isoform X1. (665 aa) |
| | LOC111184995 | Tryptase-2-like; Belongs to the peptidase S1 family. (275 aa) |
| | NXT1 | NTF2-related export protein 1 isoform X1. (222 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein isoform X1. (581 aa) |
| | CREBBP | CREB-binding protein isoform X1. (2442 aa) |
| | LOC111185731 | C-C motif chemokine. (99 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (807 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (452 aa) |
| | EP300 | Histone acetyltransferase p300. (2420 aa) |
| | LOC111185435 | Tumor necrosis factor receptor superfamily member 10A-like isoform X1. (454 aa) |
| | LOC111185436 | Tumor necrosis factor receptor superfamily member 10B-like isoform X1. (456 aa) |
| | RAE1 | mRNA export factor. (368 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (265 aa) |
| | CXCL10 | C-X-C motif chemokine. (103 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | XPO1 | Exportin-1 isoform X1. (1071 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (109 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (266 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
