Your Input: | |
| | USP7 | LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 7; Belongs to the peptidase C19 family. (1102 aa) |
| | RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (430 aa) |
| | IFNAR1 | Interferon alpha/beta receptor 1 isoform X1. (561 aa) |
| | E2F2 | Transcription factor E2F2 isoform X1. (437 aa) |
| | IFNAR2 | Interferon alpha/beta receptor 2 isoform X1. (594 aa) |
| | IRF9 | LOW QUALITY PROTEIN: interferon regulatory factor 9. (479 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa) |
| | PSMC2 | 26S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | LOC111164829 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (473 aa) |
| | LOC111163130 | Interferon alpha-1-like. (226 aa) |
| | MAP2K7 | Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (458 aa) |
| | TYK2 | Tyrosine-protein kinase. (1188 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (536 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | TNFAIP3 | Tumor necrosis factor alpha-induced protein 3. (785 aa) |
| | LOC111166690 | H-2 class I histocompatibility antigen, Q10 alpha chain-like isoform X1; Belongs to the MHC class I family. (559 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (723 aa) |
| | TAB2 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1. (693 aa) |
| | CD3D | T-cell surface glycoprotein CD3 delta chain. (171 aa) |
| | CD3G | T-cell surface glycoprotein CD3 gamma chain. (178 aa) |
| | LOC111164824 | Histone deacetylase 2-like isoform X1. (260 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain. (197 aa) |
| | LYN | Tyrosine-protein kinase. (518 aa) |
| | GADD45G | Growth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa) |
| | JAK3 | Tyrosine-protein kinase. (1104 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (464 aa) |
| | CALR | Calreticulin. (417 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | CD247 | T-cell surface glycoprotein CD3 zeta chain isoform X1. (185 aa) |
| | IRF7 | Interferon regulatory factor 7 isoform X1. (473 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | CD40 | Tumor necrosis factor receptor superfamily member 5 isoform X1. (284 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14 isoform X1. (961 aa) |
| | SYK | Tyrosine-protein kinase. (626 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1. (725 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | LOC111170864 | Recombining binding protein suppressor of hairless isoform X1. (500 aa) |
| | GADD45B | Growth arrest and DNA damage-inducible protein GADD45 beta. (160 aa) |
| | LOC111171351 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (113 aa) |
| | LOC111170644 | BOLA class I histocompatibility antigen, alpha chain BL3-7-like isoform X1; Belongs to the MHC class I family. (360 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | STAT1 | Signal transducer and activator of transcription. (749 aa) |
| | CASP8 | Caspase-8; Belongs to the peptidase C14A family. (486 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (527 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (954 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X1. (334 aa) |
| | IKBKG | NF-kappa-B essential modulator isoform X1. (412 aa) |
| | LOC111171121 | Interferon alpha-1-like. (133 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa) |
| | PSMC6 | 26S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa) |
| | CIR1 | Corepressor interacting with RBPJ 1. (448 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | STAT2 | Signal transducer and activator of transcription. (911 aa) |
| | LOC111171122 | Interferon alpha-1-like isoform X1. (195 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | CASP3 | Caspase-3 isoform X1; Belongs to the peptidase C14A family. (412 aa) |
| | HES1 | Transcription factor HES-1. (280 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (882 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 isoform X1. (452 aa) |
| | IFNB1 | Interferon beta. (185 aa) |
| | LOC111174575 | Cytochrome c-like. (69 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform X1. (460 aa) |
| | NFKB2 | Nuclear factor NF-kappa-B p100 subunit isoform X1. (900 aa) |
| | BLNK | B-cell linker protein isoform X1. (528 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (393 aa) |
| | LOC111172911 | Cytochrome c 2; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | EIF2AK2 | Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (539 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1. (461 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa) |
| | NFKBIA | NF-kappa-B inhibitor alpha. (314 aa) |
| | JUN | Transcription factor AP-1; Belongs to the bZIP family. (343 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CCNA1 | cyclin-A1; Belongs to the cyclin family. (421 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa) |
| | TBK1 | Serine/threonine-protein kinase TBK1. (729 aa) |
| | LOC111174031 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | LOC111174197 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (102 aa) |
| | CCND2 | G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa) |
| | SNW1 | SNW domain-containing protein 1. (536 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (541 aa) |
| | LOC111175930 | Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8 isoform X1; Belongs to the GDA1/CD39 NTPase family. (723 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa) |
| | LOC111178659 | Antigen peptide transporter 2-like isoform X4. (758 aa) |
| | LOC111178664 | HLA class II histocompatibility antigen, DM beta chain isoform X1. (263 aa) |
| | BAK1 | Bcl-2 homologous antagonist/killer isoform X1. (239 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase NEDD4 isoform X3. (1319 aa) |
| | CCND3 | G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (292 aa) |
| | BTK | Tyrosine-protein kinase. (687 aa) |
| | LOC111178928 | DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa) |
| | LOC111178931 | HLA class II histocompatibility antigen, DR alpha chain; Belongs to the MHC class II family. (253 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha. (165 aa) |
| | SIN3A | Paired amphipathic helix protein Sin3a. (1274 aa) |
| | LOC111178668 | HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | NFKBIE | NF-kappa-B inhibitor epsilon isoform X1. (365 aa) |
| | LOC111178925 | boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X2. (276 aa) |
| | LOC111178929 | HLA class II histocompatibility antigen, DRB1-4 beta chain-like isoform X1. (231 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (198 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7. (322 aa) |
| | TAP1 | Antigen peptide transporter 1 isoform X1. (750 aa) |
| | TAPBP | Tapasin isoform X1. (451 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa) |
| | CD58 | Lymphocyte function-associated antigen 3 isoform X1. (242 aa) |
| | LOC111178666 | HLA class II histocompatibility antigen, DM alpha chain isoform X1; Belongs to the MHC class II family. (261 aa) |
| | PSMC4 | 26S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (418 aa) |
| | NFKBIB | NF-kappa-B inhibitor beta. (353 aa) |
| | CDK6 | Cyclin-dependent kinase 6 isoform X1; Belongs to the protein kinase superfamily. (326 aa) |
| | IRF3 | Interferon regulatory factor 3 isoform X1. (464 aa) |
| | JAK1 | Tyrosine-protein kinase. (1153 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (972 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (404 aa) |
| | CCNE1 | G1/S-specific cyclin-E1 isoform X1; Belongs to the cyclin family. (410 aa) |
| | BAX | Apoptosis regulator BAX isoform X2. (223 aa) |
| | LOC111178927 | HLA class II histocompatibility antigen, DQ alpha 2 chain; Belongs to the MHC class II family. (255 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (315 aa) |
| | CD44 | CD44 antigen isoform X1. (742 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | SEM1 | 26S proteasome complex subunit SEM1 isoform X1. (100 aa) |
| | BCL2 | Apoptosis regulator Bcl-2. (233 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (561 aa) |
| | RIPK1 | Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (687 aa) |
| | CD19 | B-lymphocyte antigen CD19 isoform X1. (570 aa) |
| | LOC111180543 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa) |
| | LOC111181647 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6 isoform X1; Belongs to the protein kinase superfamily. (368 aa) |
| | E2F3 | LOW QUALITY PROTEIN: transcription factor E2F3. (461 aa) |
| | LOC111181648 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa) |
| | ITGAL | Integrin alpha-L; Belongs to the integrin alpha chain family. (1166 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1. (192 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | RELA | Transcription factor p65 isoform X1. (562 aa) |
| | PSMC3 | 26S proteasome regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (423 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12. (456 aa) |
| | CR2 | Complement receptor type 2 isoform X1. (1471 aa) |
| | LOC111184277 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (118 aa) |
| | RBPJL | Recombining binding protein suppressor of hairless-like protein. (516 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X1. (457 aa) |
| | E2F1 | Transcription factor E2F1. (437 aa) |
| | POLK | DNA polymerase kappa. (878 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X4; Belongs to the protein kinase superfamily. (410 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | MAVS | Mitochondrial antiviral-signaling protein isoform X1. (581 aa) |
| | SAP30 | Histone deacetylase complex subunit SAP30. (223 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa) |
| | TAB1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform X1. (504 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1. (807 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (452 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (456 aa) |
| | BCL2L11 | Bcl-2-like protein 11 isoform X1. (288 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (422 aa) |
| | ADRM1 | Proteasomal ubiquitin receptor ADRM1. (407 aa) |
| | CXCL10 | C-X-C motif chemokine. (103 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (366 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X1. (436 aa) |
| | APAF1 | Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (919 aa) |
| | TLR2 | Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (387 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (208 aa) |
