STRINGSTRING
LAMA1 LAMA1 ACTN2 ACTN2 ITGA9 ITGA9 RYR2 RYR2 CACNB1 CACNB1 JUP JUP TCF7L1 TCF7L1 CTNNA2 CTNNA2 CACNA2D1 CACNA2D1 LMNA LMNA GJA1 GJA1 ITGA3 ITGA3 CACNA1S CACNA1S DMD DMD CTNNB1 CTNNB1 CACNA1F CACNA1F SGCB SGCB LAMA2 LAMA2 ACTB ACTB ITGA2B ITGA2B EMD EMD LEF1 LEF1 DES DES ITGB5 ITGB5 ITGA4 ITGA4 ITGAV ITGAV CACNB4 CACNB4 SLC8A3 SLC8A3 TCF7L2 TCF7L2 ITGB7 ITGB7 CACNB3 CACNB3 DAG1 DAG1 ITGB6 ITGB6 CACNA2D2 CACNA2D2 CACNA1D CACNA1D ITGA7 ITGA7 ITGA6 ITGA6 CACNA2D3 CACNA2D3 SGCG SGCG CACNA1C CACNA1C SLC8A1 SLC8A1 ITGA11 ITGA11 PKP2 PKP2 ITGA8 ITGA8 LOC111178986 LOC111178986 ITGA10 ITGA10 ITGB1 ITGB1 CACNB2 CACNB2 CACNG6 CACNG6 DSP DSP CACNG8 CACNG8 DSG2 DSG2 CACNG3 CACNG3 DSC2 DSC2 TCF7 TCF7 ITGB3 ITGB3 SLC8A2 SLC8A2 CTNNA1 CTNNA1 CACNG7 CACNG7 CDH2 CDH2 CACNG5 CACNG5 ACTG1 ACTG1 ITGB8 ITGB8 CTNNA3 CTNNA3 ACTN3 ACTN3 ATP2A1 ATP2A1 CACNG1 CACNG1 SGCD SGCD CACNG4 CACNG4 ATP2A3 ATP2A3 ITGA2 ITGA2 ITGA1 ITGA1 ATP2A2 ATP2A2 CACNG2 CACNG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LAMA1Laminin subunit alpha-1 isoform X1. (3081 aa)
ACTN2Alpha-actinin-2. (894 aa)
ITGA9Integrin alpha-9; Belongs to the integrin alpha chain family. (1035 aa)
RYR2Ryanodine receptor 2 isoform X1. (4965 aa)
CACNB1Voltage-dependent L-type calcium channel subunit beta-1 isoform X1. (597 aa)
JUPJunction plakoglobin. (744 aa)
TCF7L1Transcription factor 7-like 1 isoform X1. (601 aa)
CTNNA2Catenin alpha-2. (865 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1097 aa)
LMNALamin; Belongs to the intermediate filament family. (664 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
ITGA3Integrin alpha-3 isoform X1; Belongs to the integrin alpha chain family. (1068 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
DMDDystrophin isoform X1. (3714 aa)
CTNNB1Catenin beta-1. (781 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1911 aa)
SGCBBeta-sarcoglycan. (329 aa)
LAMA2Laminin subunit alpha-2. (3008 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1034 aa)
EMDEmerin isoform X1. (261 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (414 aa)
DESDesmin; Belongs to the intermediate filament family. (470 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (800 aa)
ITGA4Integrin alpha-4 isoform X1; Belongs to the integrin alpha chain family. (1033 aa)
ITGAVIntegrin alpha-V isoform X2; Belongs to the integrin alpha chain family. (1048 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
SLC8A3Sodium/calcium exchanger 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (920 aa)
TCF7L2Transcription factor 7-like 2 isoform X1. (668 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (819 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
DAG1Dystroglycan. (895 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (808 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1156 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2183 aa)
ITGA7Integrin alpha-7 isoform X1; Belongs to the integrin alpha chain family. (1141 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1091 aa)
CACNA2D3Voltage-dependent calcium channel subunit alpha-2/delta-3 isoform X3. (1091 aa)
SGCGGamma-sarcoglycan isoform X1. (291 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2255 aa)
SLC8A1Sodium/calcium exchanger 1 isoform X7; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1004 aa)
ITGA11Integrin alpha-11; Belongs to the integrin alpha chain family. (1188 aa)
PKP2Plakophilin-2 isoform X1. (826 aa)
ITGA8Integrin alpha-8 isoform X1; Belongs to the integrin alpha chain family. (1062 aa)
LOC111178986LOW QUALITY PROTEIN: catenin alpha-1-like. (908 aa)
ITGA10Integrin alpha-10; Belongs to the integrin alpha chain family. (1167 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (604 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (255 aa)
DSPDesmoplakin isoform X1. (2874 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (496 aa)
DSG2Desmoglein-2. (1116 aa)
CACNG3Voltage-dependent calcium channel gamma-3 subunit isoform X1. (315 aa)
DSC2Desmocollin-2 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (908 aa)
TCF7Transcription factor 7 isoform X1. (415 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (789 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
CTNNA1Catenin alpha-1. (906 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit isoform X1. (275 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
CTNNA3Catenin alpha-3. (944 aa)
ACTN3Alpha-actinin-3 isoform X1. (902 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1006 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
SGCDDelta-sarcoglycan isoform X1. (299 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (375 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1057 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1179 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
Your Current Organism:
Delphinapterus leucas
NCBI taxonomy Id: 9749
Other names: D. leucas, beluga, beluga whale, white whale
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