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NUDT16 NUDT16 ADSS ADSS AMPD1 AMPD1 NT5C1A NT5C1A IMPDH1 IMPDH1 PNP PNP PDE10A PDE10A LOC102975756 LOC102975756 GMPS GMPS NT5C3A NT5C3A PDE7A PDE7A ENPP3 ENPP3 APRT APRT ADSS1 ADSS1 PDE5A PDE5A NT5C NT5C DGUOK DGUOK ENTPD6 ENTPD6 ATIC ATIC ADSL ADSL ENTPD4 ENTPD4 NT5E NT5E ENTPD8 ENTPD8 AMPD2 AMPD2 ENTPD3 ENTPD3 PDE2A PDE2A LOC102992058 LOC102992058 LOC102985101 LOC102985101 ADK ADK NT5C2 NT5C2 NT5C3B NT5C3B GMPR2 GMPR2 IMPDH2 IMPDH2 ENTPD5 ENTPD5 CANT1 CANT1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NUDT16U8 snoRNA-decapping enzyme. (195 aa)
ADSSAdenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
AMPD1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (779 aa)
NT5C1ACytosolic 5'-nucleotidase 1A. (365 aa)
IMPDH1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (571 aa)
PNPPurine nucleoside phosphorylase. (96 aa)
PDE10APhosphodiesterase. (790 aa)
LOC102975756Hypoxanthine-guanine phosphoribosyltransferase-like. (227 aa)
GMPSGMP synthase [glutamine-hydrolyzing]. (693 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
PDE7APhosphodiesterase. (483 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (874 aa)
APRTAdenine phosphoribosyltransferase isoform X2. (180 aa)
ADSS1Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
PDE5APhosphodiesterase. (865 aa)
NT5C5'(3')-deoxyribonucleotidase, cytosolic type isoform X1. (214 aa)
DGUOKDeoxyguanosine kinase, mitochondrial isoform X2. (280 aa)
ENTPD6Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (483 aa)
ATICBifunctional purine biosynthesis protein PURH. (592 aa)
ADSLAdenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (514 aa)
ENTPD4Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family. (616 aa)
NT5E5'-nucleotidase; Belongs to the 5'-nucleotidase family. (574 aa)
ENTPD8Ectonucleoside triphosphate diphosphohydrolase 8 isoform X1; Belongs to the GDA1/CD39 NTPase family. (494 aa)
AMPD2AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (799 aa)
ENTPD3Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa)
PDE2APhosphodiesterase. (941 aa)
LOC102992058Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
LOC102985101Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
ADKAdenosine kinase isoform X5. (362 aa)
NT5C2Cytosolic purine 5'-nucleotidase isoform X1. (573 aa)
NT5C3B5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa)
GMPR2GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (340 aa)
IMPDH2Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa)
ENTPD5Ectonucleoside triphosphate diphosphohydrolase 5 isoform X1; Belongs to the GDA1/CD39 NTPase family. (428 aa)
CANT1Soluble calcium-activated nucleotidase 1 isoform X1. (401 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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