STRINGSTRING
LOC114484769 LOC114484769 AK2 AK2 AK6 AK6 HDDC3 HDDC3 NUDT2 NUDT2 PDE7B PDE7B NME7 NME7 RRM2B RRM2B CTPS2 CTPS2 ENPP1 ENPP1 AK8 AK8 AK3 AK3 AK1 AK1 NME3 NME3 AK9-2 AK9-2 NTPCR NTPCR RRM2 RRM2 LOC112062924 LOC112062924 LOC112063121 LOC112063121 ENTPD2 ENTPD2 NME2 NME2 NME1 NME1 AK5 AK5 RRM1 RRM1 AK7 AK7 ENTPD1 ENTPD1 NME4 NME4 AK4 AK4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
LOC114484769Adenylate kinase 4-like; Belongs to the adenylate kinase family. (143 aa)
AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (241 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
HDDC3guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase MESH1. (179 aa)
NUDT2Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Belongs to the Nudix hydrolase family. (147 aa)
PDE7BPhosphodiesterase. (500 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (377 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B. (351 aa)
CTPS2CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (925 aa)
AK8Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family. (479 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (211 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
AK9-2Adenylate/nucleoside-diphosphate kinase. (294 aa)
NTPCRCancer-related nucleoside-triphosphatase isoform X2. (190 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2 isoform X1. (408 aa)
LOC112062924CTP synthase 1-B-like. (150 aa)
LOC112063121Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (838 aa)
ENTPD2LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (481 aa)
NME2Nucleoside diphosphate kinase. (152 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
AK5Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (561 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
AK7Adenylate kinase 7 isoform X1. (722 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1 isoform X1; Belongs to the GDA1/CD39 NTPase family. (513 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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