22 items (Physeter catodon) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	ADA	Adenosine deaminase isoform X2. (352 aa)
	LOC102994250	Trifunctional purine biosynthetic protein adenosine-3 isoform X1. (433 aa)
	URAD	LOW QUALITY PROTEIN: putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase. (167 aa)
	LOC102983042	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (299 aa)
	ENSPCTP00005016643	annotation not available (141 aa)
	XDH	Xanthine dehydrogenase/oxidase. (219 aa)
	ENSPCTP00005012780	annotation not available (218 aa)
	APRT	Adenine phosphoribosyltransferase isoform X2. (180 aa)
	SHMT1	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
	PPAT	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (540 aa)
	GART	Trifunctional purine biosynthetic protein adenosine-3. (437 aa)
	LOC102975756	Hypoxanthine-guanine phosphoribosyltransferase-like. (227 aa)
	GDA	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (472 aa)
	DPYD	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
	PRTFDC1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
	ENSPCTP00005000448	annotation not available (191 aa)
	ENSPCTP00005000408	annotation not available (218 aa)
	GMPR2	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (340 aa)
	ADK	Adenosine kinase isoform X5. (362 aa)
	LOC102985101	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	LOC102992058	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	SHMT2	Serine hydroxymethyltransferase, mitochondrial. (504 aa)

Your Current Organism:

Physeter catodon

NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADA	ADK	ENSPCTP00005021172	ENSPCTP00005028593	Adenosine deaminase isoform X2.	Adenosine kinase isoform X5.	0.841
ADA	APRT	ENSPCTP00005021172	ENSPCTP00005008911	Adenosine deaminase isoform X2.	Adenine phosphoribosyltransferase isoform X2.	0.878
ADA	GART	ENSPCTP00005021172	ENSPCTP00005004913	Adenosine deaminase isoform X2.	Trifunctional purine biosynthetic protein adenosine-3.	0.446
ADA	GDA	ENSPCTP00005021172	ENSPCTP00005003024	Adenosine deaminase isoform X2.	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	0.465
ADA	LOC102983042	ENSPCTP00005021172	ENSPCTP00005017790	Adenosine deaminase isoform X2.	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.	0.494
ADA	LOC102994250	ENSPCTP00005021172	ENSPCTP00005019288	Adenosine deaminase isoform X2.	Trifunctional purine biosynthetic protein adenosine-3 isoform X1.	0.446
ADK	ADA	ENSPCTP00005028593	ENSPCTP00005021172	Adenosine kinase isoform X5.	Adenosine deaminase isoform X2.	0.841
ADK	APRT	ENSPCTP00005028593	ENSPCTP00005008911	Adenosine kinase isoform X5.	Adenine phosphoribosyltransferase isoform X2.	0.981
ADK	GART	ENSPCTP00005028593	ENSPCTP00005004913	Adenosine kinase isoform X5.	Trifunctional purine biosynthetic protein adenosine-3.	0.418
ADK	LOC102994250	ENSPCTP00005028593	ENSPCTP00005019288	Adenosine kinase isoform X5.	Trifunctional purine biosynthetic protein adenosine-3 isoform X1.	0.418
APRT	ADA	ENSPCTP00005008911	ENSPCTP00005021172	Adenine phosphoribosyltransferase isoform X2.	Adenosine deaminase isoform X2.	0.878
APRT	ADK	ENSPCTP00005008911	ENSPCTP00005028593	Adenine phosphoribosyltransferase isoform X2.	Adenosine kinase isoform X5.	0.981
APRT	DPYD	ENSPCTP00005008911	ENSPCTP00005002884	Adenine phosphoribosyltransferase isoform X2.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.554
APRT	GART	ENSPCTP00005008911	ENSPCTP00005004913	Adenine phosphoribosyltransferase isoform X2.	Trifunctional purine biosynthetic protein adenosine-3.	0.848
APRT	GDA	ENSPCTP00005008911	ENSPCTP00005003024	Adenine phosphoribosyltransferase isoform X2.	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.	0.964
APRT	GMPR2	ENSPCTP00005008911	ENSPCTP00005030535	Adenine phosphoribosyltransferase isoform X2.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.	0.951
APRT	LOC102975756	ENSPCTP00005008911	ENSPCTP00005003343	Adenine phosphoribosyltransferase isoform X2.	Hypoxanthine-guanine phosphoribosyltransferase-like.	0.926
APRT	LOC102983042	ENSPCTP00005008911	ENSPCTP00005017790	Adenine phosphoribosyltransferase isoform X2.	Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family.	0.790
APRT	LOC102985101	ENSPCTP00005008911	ENSPCTP00005026806	Adenine phosphoribosyltransferase isoform X2.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.926
APRT	LOC102992058	ENSPCTP00005008911	ENSPCTP00005026401	Adenine phosphoribosyltransferase isoform X2.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.926