13 items (Physeter catodon) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRTFDC1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
	ENSPCTP00005000408	annotation not available (218 aa)
	ADK	Adenosine kinase isoform X5. (362 aa)
	LOC102985101	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	LOC102992058	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	PGM2	Phosphoglucomutase-2 isoform X1. (616 aa)
	MTAP	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (377 aa)
	ENSPCTP00005012780	annotation not available (218 aa)
	APRT	Adenine phosphoribosyltransferase isoform X2. (180 aa)
	ENSPCTP00005003355	annotation not available (97 aa)
	LOC102975756	Hypoxanthine-guanine phosphoribosyltransferase-like. (227 aa)
	PNP	Purine nucleoside phosphorylase. (96 aa)
	ENSPCTP00005000448	annotation not available (191 aa)

Your Current Organism:

Physeter catodon

NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADK	APRT	ENSPCTP00005028593	ENSPCTP00005008911	Adenosine kinase isoform X5.	Adenine phosphoribosyltransferase isoform X2.	0.981
ADK	ENSPCTP00005003355	ENSPCTP00005028593	ENSPCTP00005003355	Adenosine kinase isoform X5.	annotation not available	0.468
ADK	MTAP	ENSPCTP00005028593	ENSPCTP00005023281	Adenosine kinase isoform X5.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.611
ADK	PGM2	ENSPCTP00005028593	ENSPCTP00005024810	Adenosine kinase isoform X5.	Phosphoglucomutase-2 isoform X1.	0.468
ADK	PNP	ENSPCTP00005028593	ENSPCTP00005003218	Adenosine kinase isoform X5.	Purine nucleoside phosphorylase.	0.976
APRT	ADK	ENSPCTP00005008911	ENSPCTP00005028593	Adenine phosphoribosyltransferase isoform X2.	Adenosine kinase isoform X5.	0.981
APRT	LOC102975756	ENSPCTP00005008911	ENSPCTP00005003343	Adenine phosphoribosyltransferase isoform X2.	Hypoxanthine-guanine phosphoribosyltransferase-like.	0.926
APRT	LOC102985101	ENSPCTP00005008911	ENSPCTP00005026806	Adenine phosphoribosyltransferase isoform X2.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.926
APRT	LOC102992058	ENSPCTP00005008911	ENSPCTP00005026401	Adenine phosphoribosyltransferase isoform X2.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.926
APRT	MTAP	ENSPCTP00005008911	ENSPCTP00005023281	Adenine phosphoribosyltransferase isoform X2.	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.969
APRT	PNP	ENSPCTP00005008911	ENSPCTP00005003218	Adenine phosphoribosyltransferase isoform X2.	Purine nucleoside phosphorylase.	0.990
ENSPCTP00005000408	MTAP	ENSPCTP00005000408	ENSPCTP00005023281	annotation not available	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.563
ENSPCTP00005000408	PNP	ENSPCTP00005000408	ENSPCTP00005003218	annotation not available	Purine nucleoside phosphorylase.	0.556
ENSPCTP00005000448	MTAP	ENSPCTP00005000448	ENSPCTP00005023281	annotation not available	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.563
ENSPCTP00005000448	PNP	ENSPCTP00005000448	ENSPCTP00005003218	annotation not available	Purine nucleoside phosphorylase.	0.556
ENSPCTP00005003355	ADK	ENSPCTP00005003355	ENSPCTP00005028593	annotation not available	Adenosine kinase isoform X5.	0.468
ENSPCTP00005003355	MTAP	ENSPCTP00005003355	ENSPCTP00005023281	annotation not available	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.555
ENSPCTP00005003355	PNP	ENSPCTP00005003355	ENSPCTP00005003218	annotation not available	Purine nucleoside phosphorylase.	0.595
ENSPCTP00005012780	MTAP	ENSPCTP00005012780	ENSPCTP00005023281	annotation not available	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.563
ENSPCTP00005012780	PNP	ENSPCTP00005012780	ENSPCTP00005003218	annotation not available	Purine nucleoside phosphorylase.	0.556