49 items (Physeter catodon) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC112063265	Uridine phosphorylase 1-like. (169 aa)
	DCK	Deoxycytidine kinase isoform X1. (376 aa)
	NME7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (377 aa)
	ENSPCTP00005006311	annotation not available (94 aa)
	DCTD	Deoxycytidylate deaminase. (178 aa)
	NT5M	5'(3')-deoxyribonucleotidase, mitochondrial. (228 aa)
	CTPS2	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (586 aa)
	ENPP3	Ectonucleotide pyrophosphatase/phosphodiesterase family member 3. (874 aa)
	UMPS	Uridine 5'-monophosphate synthase. (480 aa)
	TBPL1	TATA box-binding protein-like protein 1. (186 aa)
	CAD	CAD protein isoform X2. (2225 aa)
	NT5C	5'(3')-deoxyribonucleotidase, cytosolic type isoform X1. (214 aa)
	UCK1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
	UPP2	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (318 aa)
	ENSPCTP00005011914	annotation not available (109 aa)
	LOC102976077	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial-like. (165 aa)
	NME3	Nucleoside diphosphate kinase. (169 aa)
	CMPK2	UMP-CMP kinase 2, mitochondrial. (447 aa)
	DCTPP1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (169 aa)
	ENSPCTP00005018272	annotation not available (153 aa)
	ENSPCTP00005003046	annotation not available (114 aa)
	LOC112062924	CTP synthase 1-B-like. (150 aa)
	CMPK1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (313 aa)
	LOC114485901	Uracil phosphoribosyltransferase-like. (156 aa)
	DTYMK	Thymidylate kinase isoform X3. (212 aa)
	UPRT	Uracil phosphoribosyltransferase homolog. (307 aa)
	ENTPD4	Ectonucleoside triphosphate diphosphohydrolase 4 isoform X1; Belongs to the GDA1/CD39 NTPase family. (616 aa)
	DUT	Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X2. (167 aa)
	NME5	Nucleoside diphosphate kinase homolog 5; Belongs to the NDK family. (233 aa)
	LOC112062733	Uridine phosphorylase 1-like. (169 aa)
	DPYD	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
	UCK2	Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
	ENSPCTP00005002743	annotation not available (205 aa)
	CTPS1	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (700 aa)
	NME9	Thioredoxin domain-containing protein 6 isoform X1; Belongs to the NDK family. (329 aa)
	LOC112062886	Nucleoside diphosphate kinase. (154 aa)
	NME6	Nucleoside diphosphate kinase. (186 aa)
	NME4	Nucleoside diphosphate kinase. (187 aa)
	ENTPD5	Ectonucleoside triphosphate diphosphohydrolase 5 isoform X1; Belongs to the GDA1/CD39 NTPase family. (428 aa)
	ENSPCTP00005030070	annotation not available (142 aa)
	UPB1	Beta-ureidopropionase. (378 aa)
	DPYS	Dihydropyrimidinase isoform X1. (519 aa)
	DHODH	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (395 aa)
	LOC112062729	Uridine phosphorylase 1-like. (169 aa)
	TYMS	Thymidylate synthase. (315 aa)
	UCKL1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (549 aa)
	NME1	Nucleoside diphosphate kinase. (152 aa)
	NME2	Nucleoside diphosphate kinase. (152 aa)
	ENTPD7	Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (605 aa)

Your Current Organism:

Physeter catodon

NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAD	CTPS1	ENSPCTP00005008754	ENSPCTP00005000754	CAD protein isoform X2.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.648
CAD	CTPS2	ENSPCTP00005008754	ENSPCTP00005007059	CAD protein isoform X2.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.415
CAD	DHODH	ENSPCTP00005008754	ENSPCTP00005026834	CAD protein isoform X2.	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.	0.990
CAD	DPYD	ENSPCTP00005008754	ENSPCTP00005002884	CAD protein isoform X2.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.856
CAD	DPYS	ENSPCTP00005008754	ENSPCTP00005028150	CAD protein isoform X2.	Dihydropyrimidinase isoform X1.	0.652
CAD	ENSPCTP00005006311	ENSPCTP00005008754	ENSPCTP00005006311	CAD protein isoform X2.	annotation not available	0.407
CAD	ENSPCTP00005011914	ENSPCTP00005008754	ENSPCTP00005011914	CAD protein isoform X2.	annotation not available	0.811
CAD	LOC112062924	ENSPCTP00005008754	ENSPCTP00005018872	CAD protein isoform X2.	CTP synthase 1-B-like.	0.415
CAD	NME6	ENSPCTP00005008754	ENSPCTP00005021759	CAD protein isoform X2.	Nucleoside diphosphate kinase.	0.407
CAD	TYMS	ENSPCTP00005008754	ENSPCTP00005025775	CAD protein isoform X2.	Thymidylate synthase.	0.449
CAD	UCK1	ENSPCTP00005008754	ENSPCTP00005011310	CAD protein isoform X2.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.460
CAD	UCK2	ENSPCTP00005008754	ENSPCTP00005002867	CAD protein isoform X2.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.460
CAD	UCKL1	ENSPCTP00005008754	ENSPCTP00005024018	CAD protein isoform X2.	Uridine-cytidine kinase; Belongs to the uridine kinase family.	0.452
CAD	UMPS	ENSPCTP00005008754	ENSPCTP00005008155	CAD protein isoform X2.	Uridine 5'-monophosphate synthase.	0.834
CAD	UPP2	ENSPCTP00005008754	ENSPCTP00005011418	CAD protein isoform X2.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.531
CAD	UPRT	ENSPCTP00005008754	ENSPCTP00005020784	CAD protein isoform X2.	Uracil phosphoribosyltransferase homolog.	0.495
CMPK1	CMPK2	ENSPCTP00005020447	ENSPCTP00005015425	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	UMP-CMP kinase 2, mitochondrial.	0.957
CMPK1	CTPS1	ENSPCTP00005020447	ENSPCTP00005000754	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.411
CMPK1	CTPS2	ENSPCTP00005020447	ENSPCTP00005007059	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.411
CMPK1	DCK	ENSPCTP00005020447	ENSPCTP00005003311	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxycytidine kinase isoform X1.	0.954