STRINGSTRING
EMC4 EMC4 REEP4 REEP4 ESYT3 ESYT3 CAV2 CAV2 GET3 GET3 SPTSSB SPTSSB COL4A3BP COL4A3BP BNIP1 BNIP1 MIA3 MIA3 RETREG1 RETREG1 LMAN2 LMAN2 PCNX1 PCNX1 VCPIP1 VCPIP1 UMOD UMOD C17H16orf74 C17H16orf74 EMC6 EMC6 TRAM2 TRAM2 POLR2M POLR2M ESYT2 ESYT2 TMCC1 TMCC1 REEP1 REEP1 ATL2 ATL2 TRAM1L1 TRAM1L1 WRB WRB RNF112 RNF112 PCNX4 PCNX4 LNPK LNPK LMAN1 LMAN1 TMEM38A TMEM38A LMAN2L LMAN2L EMC3 EMC3 ENSPCTP00005012873 ENSPCTP00005012873 SEC16A SEC16A SEC31A SEC31A ENSPCTP00005013750 ENSPCTP00005013750 LOC102980464 LOC102980464 GET4 GET4 RETREG3 RETREG3 GRAMD2A GRAMD2A TOR1B TOR1B CAMLG CAMLG ENSPCTP00005016068 ENSPCTP00005016068 ATL3 ATL3 ENSPCTP00005016203 ENSPCTP00005016203 RTN3 RTN3 EMC8 EMC8 LOC102983997 LOC102983997 TMEM33 TMEM33 CCDC47 CCDC47 BAG6 BAG6 TRAM1 TRAM1 JAGN1 JAGN1 TMEM170A TMEM170A CASQ1 CASQ1 ZFYVE27 ZFYVE27 UBL4A UBL4A ATL1 ATL1 CACNA1S CACNA1S EMC1 EMC1 SEC16B SEC16B LOC114486467 LOC114486467 ENSPCTP00005022529 ENSPCTP00005022529 PEX5 PEX5 ESYT1 ESYT1 TMEM38B TMEM38B EMC10 EMC10 SEC31B SEC31B WDR83OS WDR83OS EMC2 EMC2 TOR1AIP2 TOR1AIP2 PCNX3 PCNX3 REEP5 REEP5 LRRK2 LRRK2 VAPB VAPB STX18 STX18 LPCAT3 LPCAT3 RETREG2 RETREG2 SGTA SGTA RTN4 RTN4 REEP2 REEP2 C21HXorf56 C21HXorf56 EMC9 EMC9 SEC61A1 SEC61A1 SHTN1 SHTN1 RAB10 RAB10 REEP3 REEP3 LMAN1L LMAN1L TEX28 TEX28 MOSPD3 MOSPD3 EMC7 EMC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EMC4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (183 aa)
REEP4Receptor expression-enhancing protein. (296 aa)
ESYT3Extended synaptotagmin-3 isoform X2. (886 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
GET3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa)
SPTSSBSerine palmitoyltransferase small subunit B. (76 aa)
COL4A3BPCollagen type IV alpha-3-binding protein isoform X3. (757 aa)
BNIP1Vesicle transport protein SEC20. (228 aa)
MIA3Transport and Golgi organization protein 1 homolog isoform X3. (1947 aa)
RETREG1Reticulophagy regulator 1. (344 aa)
LMAN2Vesicular integral-membrane protein VIP36 isoform X1. (359 aa)
PCNX1Pecanex-like protein 1 isoform X1. (2341 aa)
VCPIP1Deubiquitinating protein VCIP135. (1222 aa)
UMODUromodulin. (643 aa)
C17H16orf74Uncharacterized protein C16orf74 homolog isoform X1. (170 aa)
EMC6ER membrane protein complex subunit 6. (110 aa)
TRAM2Translocating chain-associated membrane protein; Belongs to the TRAM family. (411 aa)
POLR2MProtein GRINL1A. (369 aa)
ESYT2Extended synaptotagmin-2 isoform X1. (864 aa)
TMCC1Transmembrane and coiled-coil domains protein 1 isoform X2. (653 aa)
REEP1Receptor expression-enhancing protein. (284 aa)
ATL2Atlastin-2 isoform X1. (583 aa)
TRAM1L1Translocating chain-associated membrane protein; Belongs to the TRAM family. (372 aa)
WRBTail-anchored protein insertion receptor WRB isoform X1. (243 aa)
RNF112RING finger protein 112. (629 aa)
PCNX4Pecanex-like protein 4 isoform X1. (1146 aa)
LNPKEndoplasmic reticulum junction formation protein lunapark isoform X1. (429 aa)
LMAN1Protein ERGIC-53. (519 aa)
TMEM38ATrimeric intracellular cation channel type A. (266 aa)
LMAN2LVIP36-like protein isoform X1. (188 aa)
EMC3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
ENSPCTP00005012873annotation not available (378 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2368 aa)
SEC31AProtein transport protein Sec31A isoform X2. (1252 aa)
ENSPCTP00005013750annotation not available (65 aa)
LOC102980464Peroxisomal targeting signal 1 receptor-like isoform X1. (609 aa)
GET4Golgi to ER traffic protein 4 homolog. (320 aa)
RETREG3Reticulophagy regulator 3 isoform X2. (466 aa)
GRAMD2AGRAM domain-containing protein 2A isoform X1. (415 aa)
TOR1BTorsin. (336 aa)
CAMLGCalcium signal-modulating cyclophilin ligand isoform X1. (341 aa)
ENSPCTP00005016068annotation not available (136 aa)
ATL3Atlastin-3 isoform X1. (541 aa)
ENSPCTP00005016203annotation not available (173 aa)
RTN3Reticulon 3. (1028 aa)
EMC8ER membrane protein complex subunit 8. (210 aa)
LOC102983997Pecanex-like protein 2. (423 aa)
TMEM33Transmembrane protein 33 isoform X1. (316 aa)
CCDC47Coiled-coil domain-containing protein 47. (483 aa)
BAG6Large proline-rich protein BAG6 isoform X2. (1164 aa)
TRAM1Translocating chain-associated membrane protein; Belongs to the TRAM family. (377 aa)
JAGN1Protein jagunal homolog 1 isoform X1. (183 aa)
TMEM170ATransmembrane protein 170A isoform X2. (121 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
ZFYVE27Protrudin isoform X2. (418 aa)
UBL4AUbiquitin-like protein 4A isoform X1. (195 aa)
ATL1Atlastin-1. (558 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1868 aa)
EMC1ER membrane protein complex subunit 1 isoform X5. (993 aa)
SEC16BProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1064 aa)
LOC114486467Lysophospholipid acyltransferase 5-like isoform X3. (63 aa)
ENSPCTP00005022529annotation not available (156 aa)
PEX5Peroxisomal biogenesis factor 5 isoform X1. (660 aa)
ESYT1Extended synaptotagmin-1 isoform X1. (1049 aa)
TMEM38BTrimeric intracellular cation channel type B isoform X1. (291 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (260 aa)
SEC31BLOW QUALITY PROTEIN: protein transport protein Sec31B. (1172 aa)
WDR83OSProtein Asterix. (106 aa)
EMC2ER membrane protein complex subunit 2. (329 aa)
TOR1AIP2torsin-1A-interacting protein 2. (470 aa)
PCNX3Pecanex-like protein 3 isoform X3. (2028 aa)
REEP5Receptor expression-enhancing protein. (190 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2 isoform X2. (2567 aa)
VAPBVesicle-associated membrane protein-associated protein B/C isoform X1. (243 aa)
STX18Syntaxin-18 isoform X1. (335 aa)
LPCAT3Lysophospholipid acyltransferase 5; Belongs to the membrane-bound acyltransferase family. (517 aa)
RETREG2Reticulophagy regulator 2. (544 aa)
SGTASmall glutamine-rich tetratricopeptide repeat-containing protein alpha. (313 aa)
RTN4Reticulon. (1193 aa)
REEP2Receptor expression-enhancing protein. (254 aa)
C21HXorf56UPF0428 protein CXorf56 homolog isoform X1. (222 aa)
EMC9ER membrane protein complex subunit 9. (206 aa)
SEC61A1Protein transport protein Sec61 subunit alpha. (481 aa)
SHTN1Shootin-1 isoform X2. (631 aa)
RAB10Ras-related protein Rab-10. (200 aa)
REEP3Receptor expression-enhancing protein. (255 aa)
LMAN1LProtein ERGIC-53-like isoform X1. (506 aa)
TEX28Testis-specific protein TEX28. (395 aa)
MOSPD3Motile sperm domain-containing protein 3 isoform X2. (388 aa)
EMC7ER membrane protein complex subunit 7. (241 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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