STRINGSTRING
TK1 TK1 N4BP2L1 N4BP2L1 AK5 AK5 UCKL1 UCKL1 NME1 NME1 NME2 NME2 AK4 AK4 NME4 NME4 CLP1 CLP1 AK7 AK7 NT5C2 NT5C2 ADK ADK LOC114484769 LOC114484769 LOC112062886 LOC112062886 NME9 NME9 AK2 AK2 AK6 AK6 ENSPCTP00005001421 ENSPCTP00005001421 GUK1 GUK1 ENSPCTP00005002743 ENSPCTP00005002743 UCK2 UCK2 DCK DCK NME7 NME7 LRGUK LRGUK NOL9 NOL9 ENSPCTP00005006311 ENSPCTP00005006311 AK8 AK8 AK3 AK3 DGUOK DGUOK PNKP PNKP UCK1 UCK1 AK1 AK1 TK2 TK2 NME3 NME3 CMPK2 CMPK2 AK9 AK9 AK9-2 AK9-2 REC114 REC114 CMPK1 CMPK1 DTYMK DTYMK N4BP2 N4BP2 NME5 NME5 NME6 NME6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TK1Thymidine kinase. (266 aa)
N4BP2L1NEDD4-binding protein 2-like 1 isoform X2. (242 aa)
AK5Adenylate kinase isoenzyme 5; Belongs to the adenylate kinase family. (561 aa)
UCKL1Uridine-cytidine kinase; Belongs to the uridine kinase family. (549 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
NME2Nucleoside diphosphate kinase. (152 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
NME4Nucleoside diphosphate kinase. (187 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
AK7Adenylate kinase 7 isoform X1. (722 aa)
NT5C2Cytosolic purine 5'-nucleotidase isoform X1. (573 aa)
ADKAdenosine kinase isoform X5. (362 aa)
LOC114484769Adenylate kinase 4-like; Belongs to the adenylate kinase family. (143 aa)
LOC112062886Nucleoside diphosphate kinase. (154 aa)
NME9Thioredoxin domain-containing protein 6 isoform X1; Belongs to the NDK family. (329 aa)
AK2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (241 aa)
AK6Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (172 aa)
ENSPCTP00005001421annotation not available (162 aa)
GUK1Guanylate kinase isoform X4. (198 aa)
ENSPCTP00005002743annotation not available (205 aa)
UCK2Uridine-cytidine kinase; Belongs to the uridine kinase family. (261 aa)
DCKDeoxycytidine kinase isoform X1. (376 aa)
NME7Nucleoside diphosphate kinase 7; Belongs to the NDK family. (377 aa)
LRGUKLeucine-rich repeat and guanylate kinase domain-containing protein. (831 aa)
NOL9Polynucleotide 5'-hydroxyl-kinase NOL9 isoform X4. (690 aa)
ENSPCTP00005006311annotation not available (94 aa)
AK8Adenylate kinase 8 isoform X1; Belongs to the adenylate kinase family. (479 aa)
AK3GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa)
DGUOKDeoxyguanosine kinase, mitochondrial isoform X2. (280 aa)
PNKPBifunctional polynucleotide phosphatase/kinase isoform X3. (521 aa)
UCK1Uridine-cytidine kinase; Belongs to the uridine kinase family. (277 aa)
AK1Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. (211 aa)
TK2Thymidine kinase 2, mitochondrial. (120 aa)
NME3Nucleoside diphosphate kinase. (169 aa)
CMPK2UMP-CMP kinase 2, mitochondrial. (447 aa)
AK9Adenylate kinase 9. (724 aa)
AK9-2Adenylate/nucleoside-diphosphate kinase. (294 aa)
REC114Meiotic recombination protein REC114 isoform X1. (265 aa)
CMPK1UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (313 aa)
DTYMKThymidylate kinase isoform X3. (212 aa)
N4BP2NEDD4-binding protein 2 isoform X1. (1766 aa)
NME5Nucleoside diphosphate kinase homolog 5; Belongs to the NDK family. (233 aa)
NME6Nucleoside diphosphate kinase. (186 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.