STRINGSTRING
VAMP8 VAMP8 VAMP5 VAMP5 CFTR CFTR STX7 STX7 WNK2 WNK2 WNK1 WNK1 STX8 STX8 CNTD1 CNTD1 VTI1B VTI1B WNK4 WNK4 WNK3 WNK3 STX1A STX1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VAMP8Vesicle-associated membrane protein 8 isoform X2. (100 aa)
VAMP5Vesicle-associated membrane protein 5 isoform X2. (116 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
STX7Syntaxin-7 isoform X1; Belongs to the syntaxin family. (261 aa)
WNK2Serine/threonine-protein kinase WNK2 isoform X2. (1276 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X26. (2775 aa)
STX8Syntaxin-8 isoform X1. (236 aa)
CNTD1Cyclin N-terminal domain-containing protein 1. (328 aa)
VTI1BVesicle transport through interaction with t-SNAREs homolog 1B. (232 aa)
WNK4Serine/threonine-protein kinase WNK4. (803 aa)
WNK3Serine/threonine-protein kinase WNK3. (1789 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (278 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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