STRINGSTRING
ALAS2 ALAS2 ERCC2 ERCC2 UFL1 UFL1 BAP1 BAP1 ADD1 ADD1 LOC102982823 LOC102982823 SH2B3 SH2B3 DNASE2 DNASE2 KLF1 KLF1 LYAR LYAR SLC4A1 SLC4A1 MFHAS1 MFHAS1 C15orf41 C15orf41 TSPO2 TSPO2 JAK3 JAK3 ENSPCTP00005030558 ENSPCTP00005030558 EPB42 EPB42 EPO EPO ZBTB7A ZBTB7A DMTN DMTN CDK5RAP3 CDK5RAP3 BMP4 BMP4 ZFPM1 ZFPM1 NCAPG2 NCAPG2 SRF SRF JAK2 JAK2 ARID4A ARID4A SP3 SP3 LOC102979350 LOC102979350 LOC114486069 LOC114486069 LOC112062838 LOC112062838 UBA5 UBA5 IKZF1 IKZF1 CITED2 CITED2 KMT2E KMT2E TMOD2 TMOD2 FLVCR1 FLVCR1 GATA3 GATA3 RCOR1 RCOR1 AHSP AHSP LOC102975528 LOC102975528 KIT KIT HSCB HSCB L3MBTL3 L3MBTL3 GATA1 GATA1 LYN LYN MAEA MAEA MED1 MED1 KLF2 KLF2 NCKAP1L NCKAP1L ENSPCTP00005012144 ENSPCTP00005012144 ADGRF5 ADGRF5 HCLS1 HCLS1 STAT5B STAT5B CASP3 CASP3 ETV2 ETV2 EPAS1 EPAS1 PTPN2 PTPN2 MPIG6B MPIG6B PLA2G10 PLA2G10 SMAD5 SMAD5 ADAR ADAR PKNOX1 PKNOX1 TRIM10 TRIM10 DYRK3 DYRK3 CEBPG CEBPG JMJD6 JMJD6 ENSPCTP00005020344 ENSPCTP00005020344 TAL1 TAL1 LOC114483874 LOC114483874 ABCB10 ABCB10 KCNQ1 KCNQ1 HSPA9 HSPA9 SLC25A38 SLC25A38 RB1 RB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALAS25-aminolevulinate synthase. (587 aa)
ERCC2General transcription and DNA repair factor IIH helicase subunit XPD isoform X2. (760 aa)
UFL1E3 UFM1-protein ligase 1 isoform X1. (791 aa)
BAP1Ubiquitin carboxyl-terminal hydrolase. (729 aa)
ADD1Alpha-adducin isoform X4. (696 aa)
LOC102982823Glucose-6-phosphate 1-dehydrogenase isoform X1. (329 aa)
SH2B3SH2B adapter protein 3 isoform X4. (570 aa)
DNASE2Deoxyribonuclease-2-alpha. (352 aa)
KLF1Krueppel-like factor 1. (367 aa)
LYARCell growth-regulating nucleolar protein isoform X3. (389 aa)
SLC4A1Anion exchange protein. (443 aa)
MFHAS1Malignant fibrous histiocytoma-amplified sequence 1 isoform X1. (1076 aa)
C15orf41Uncharacterized protein C15orf41 homolog isoform X1. (287 aa)
TSPO2Translocator protein 2 isoform X2. (171 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
ENSPCTP00005030558annotation not available (449 aa)
EPB42Erythrocyte membrane protein band 4.2. (688 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
ZBTB7AZinc finger and BTB domain-containing protein 7A isoform X3. (420 aa)
DMTNDematin isoform X1. (405 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3 isoform X1. (505 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ZFPM1Zinc finger protein ZFPM1. (147 aa)
NCAPG2Condensin-2 complex subunit G2 isoform X3. (1146 aa)
SRFSerum response factor isoform X1. (535 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
ARID4AAT-rich interactive domain-containing protein 4A isoform X2. (1265 aa)
SP3Transcription factor Sp3. (713 aa)
LOC102979350Transmembrane protein 14C. (114 aa)
LOC114486069Heat shock 70 kDa protein, mitochondrial-like. (1209 aa)
LOC112062838General transcription and DNA repair factor IIH helicase subunit XPD-like. (490 aa)
UBA5Ubiquitin-like modifier-activating enzyme 5. (374 aa)
IKZF1DNA-binding protein Ikaros. (519 aa)
CITED2Cbp/p300-interacting transactivator 2. (281 aa)
KMT2EInactive histone-lysine N-methyltransferase 2E isoform X1. (1857 aa)
TMOD2Tropomodulin-3. (406 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1 isoform X2. (555 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
RCOR1REST corepressor 1. (485 aa)
AHSPAlpha-hemoglobin-stabilizing protein. (92 aa)
LOC102975528Caspase-3-like; Belongs to the peptidase C14A family. (277 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
HSCBIron-sulfur cluster co-chaperone protein HscB isoform X1. (255 aa)
L3MBTL3Lethal(3)malignant brain tumor-like protein 3 isoform X2. (779 aa)
GATA1Erythroid transcription factor isoform X1. (413 aa)
LYNTyrosine-protein kinase. (512 aa)
MAEAE3 ubiquitin-protein transferase MAEA isoform X1. (434 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
KLF2Krueppel-like factor 2. (355 aa)
NCKAP1LNck-associated protein 1-like. (1128 aa)
ENSPCTP00005012144annotation not available (172 aa)
ADGRF5Adhesion G protein-coupled receptor F5 isoform X8; Belongs to the G-protein coupled receptor 2 family. (1342 aa)
HCLS1Hematopoietic lineage cell-specific protein. (481 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CASP3Caspase-3 isoform X1; Belongs to the peptidase C14A family. (277 aa)
ETV2ETS translocation variant 2 isoform X4. (153 aa)
EPAS1Endothelial PAS domain-containing protein 1. (860 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (416 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b isoform X1. (275 aa)
PLA2G10Phospholipase A(2). (159 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ADARDouble-stranded RNA-specific adenosine deaminase isoform X2. (1174 aa)
PKNOX1Homeobox protein PKNOX1 isoform X1. (436 aa)
TRIM10Tripartite motif-containing protein 10. (482 aa)
DYRK3Dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1. (587 aa)
CEBPGCCAAT/enhancer-binding protein gamma isoform X1. (149 aa)
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1. (426 aa)
ENSPCTP00005020344annotation not available (114 aa)
TAL1T-cell acute lymphocytic leukemia protein 1. (328 aa)
LOC114483874B-cell lymphoma 6 protein. (54 aa)
ABCB10ATP-binding cassette sub-family B member 10, mitochondrial isoform X1. (723 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1 isoform X1; Belongs to the potassium channel family. (676 aa)
HSPA9Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa)
SLC25A38Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (304 aa)
RB1Retinoblastoma-associated protein isoform X2. (929 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.