STRINGSTRING
MYBBP1A MYBBP1A SIK2 SIK2 IMPACT IMPACT PICK1 PICK1 PRKAG3 PRKAG3 PRKAA2 PRKAA2 ATG14 ATG14 C12orf66 C12orf66 NFE2L2 NFE2L2 SESN2 SESN2 RRP8 RRP8 ASNS ASNS SIRT1 SIRT1 MTMR3 MTMR3 ENSPCTP00005007755 ENSPCTP00005007755 ENSPCTP00005009132 ENSPCTP00005009132 EIF2AK3 EIF2AK3 XBP1 XBP1 SUV39H1 SUV39H1 TBL2 TBL2 PIK3C3 PIK3C3 PMAIP1 PMAIP1 PRKAG1 PRKAG1 BCL2 BCL2 SH3GLB1 SH3GLB1 PRKAG2 PRKAG2 BECN1 BECN1 SESN3 SESN3 HSPA5 HSPA5 LOC114485023 LOC114485023 SESN1 SESN1 FOXO3 FOXO3 PLIN3 PLIN3 ZC3H12A ZC3H12A KPTN KPTN ATF4 ATF4 BHLHA15 BHLHA15 PLIN2 PLIN2 LOC102988511 LOC102988511 LOC114485817 LOC114485817 NUAK2 NUAK2 LOC112063102 LOC112063102 SZT2 SZT2 PRKAA1 PRKAA1 LOC102976604 LOC102976604 KAT5 KAT5 SLC2A1 SLC2A1 NIM1K NIM1K NUAK1 NUAK1 ITFG2 ITFG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYBBP1ALOW QUALITY PROTEIN: myb-binding protein 1A. (1445 aa)
SIK2Serine/threonine-protein kinase SIK2 isoform X2. (906 aa)
IMPACTProtein IMPACT isoform X6. (330 aa)
PICK1PRKCA-binding protein. (417 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3 isoform X4. (486 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (510 aa)
C12orf66KICSTOR complex protein C12orf66 homolog isoform X1. (445 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2 isoform X1. (608 aa)
SESN2Sestrin-2. (471 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (458 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing] isoform X1. (561 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (731 aa)
MTMR3Myotubularin-related protein 3. (282 aa)
ENSPCTP00005007755annotation not available (145 aa)
ENSPCTP00005009132annotation not available (179 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1116 aa)
XBP1LOW QUALITY PROTEIN: X-box-binding protein 1. (379 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (449 aa)
TBL2Transducin beta-like protein 2. (447 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
PMAIP1Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (330 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (230 aa)
SH3GLB1endophilin-B1 isoform X2. (402 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2 isoform X3. (413 aa)
BECN1Beclin-1 isoform X1. (473 aa)
SESN3Sestrin-3. (492 aa)
HSPA5Endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa)
LOC1144850235'-AMP-activated protein kinase subunit gamma-2-like isoform X2. (226 aa)
SESN1Sestrin-1 isoform X1. (551 aa)
FOXO3Forkhead box protein O3 isoform X2. (672 aa)
PLIN3Perilipin; Belongs to the perilipin family. (438 aa)
ZC3H12AEndoribonuclease ZC3H12A. (583 aa)
KPTNKICSTOR complex protein kaptin. (436 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (352 aa)
BHLHA15Class A basic helix-loop-helix protein 15 isoform X3. (185 aa)
PLIN2Perilipin; Belongs to the perilipin family. (455 aa)
LOC102988511Serine/threonine-protein kinase SIK1 isoform X1. (785 aa)
LOC114485817Luminal-binding protein 4-like. (410 aa)
NUAK2NUAK family SNF1-like kinase 2. (633 aa)
LOC112063102Luminal-binding protein 5-like; Belongs to the heat shock protein 70 family. (815 aa)
SZT2KICSTOR complex protein SZT2 isoform X4. (3428 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
LOC102976604Myotubularin-related protein 3. (589 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (534 aa)
NIM1KSerine/threonine-protein kinase NIM1; Belongs to the protein kinase superfamily. (436 aa)
NUAK1NUAK family SNF1-like kinase 1 isoform X1. (609 aa)
ITFG2KICSTOR complex protein ITFG2. (444 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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