STRINGSTRING
ENSPCTP00005000539 ENSPCTP00005000539 ENSPCTP00005000780 ENSPCTP00005000780 SMOC2 SMOC2 EGFR EGFR APP APP ADAMTS1 ADAMTS1 SASS6 SASS6 ENSPCTP00005002306 ENSPCTP00005002306 ANXA1 ANXA1 UBE2E2 UBE2E2 LSM11 LSM11 KMT2E KMT2E TMOD2 TMOD2 ANKRD17 ANKRD17 PLRG1 PLRG1 CDC7 CDC7 LSM10 LSM10 DTL DTL EIF4E EIF4E ENSPCTP00005005853 ENSPCTP00005005853 BIRC5 BIRC5 ASNS ASNS TFDP1 TFDP1 RRM2B RRM2B CDC16 CDC16 USP22 USP22 CCND3 CCND3 FBXO5 FBXO5 STOX1 STOX1 MAD2L1BP MAD2L1BP CDT1 CDT1 ENSPCTP00005009816 ENSPCTP00005009816 NSMCE2 NSMCE2 CDC25B CDC25B MTA3 MTA3 ABL1 ABL1 RAD51C RAD51C PKN2 PKN2 MBLAC1 MBLAC1 VPS4B VPS4B STAT5B STAT5B CUL3 CUL3 PRKCA PRKCA STAT5A STAT5A HSF1 HSF1 ENSPCTP00005013982 ENSPCTP00005013982 ENSPCTP00005014418 ENSPCTP00005014418 POLDIP2 POLDIP2 PPP1R10 PPP1R10 FOXA1 FOXA1 MTBP MTBP ENSPCTP00005031685 ENSPCTP00005031685 CCDC57 CCDC57 MECP2 MECP2 RCC2 RCC2 ENSPCTP00005030601 ENSPCTP00005030601 ANAPC11 ANAPC11 CUL4B CUL4B USP2 USP2 CUL4A CUL4A CDK1 CDK1 MEIS2 MEIS2 ANAPC5 ANAPC5 RPTOR RPTOR RPS6KB1 RPS6KB1 ANAPC7 ANAPC7 RRM1 RRM1 CDK4 CDK4 FGF10 FGF10 DDX3X DDX3X PHB2 PHB2 CENPJ CENPJ PRAP1 PRAP1 NANOG NANOG EIF4G1 EIF4G1 UBE2C UBE2C CCDC57-2 CCDC57-2 SIN3A SIN3A KLHL18 KLHL18 RB1 RB1 BRCA2 BRCA2 EIF4EBP1 EIF4EBP1 CDC27 CDC27 CDC25A CDC25A RAB11A RAB11A LOC114485722 LOC114485722 SPHK1 SPHK1 CDC25C CDC25C CDC23 CDC23 WNT10B WNT10B NKX3-1 NKX3-1 RAD51B RAD51B ENSPCTP00005021490 ENSPCTP00005021490 LGMN LGMN LOC112063320 LOC112063320 SHB SHB STIL STIL ENSPCTP00005020162 ENSPCTP00005020162 MEPCE MEPCE CDCA5 CDCA5 LOC112063118 LOC112063118 LOC112063121 LOC112063121 ENSPCTP00005018845 ENSPCTP00005018845 AIF1 AIF1 RRM2 RRM2 PTPN11 PTPN11 DUSP3 DUSP3 CPSF3 CPSF3 CCND1 CCND1 HSPA2 HSPA2 ENSPCTP00005016806 ENSPCTP00005016806 ENSPCTP00005016805 ENSPCTP00005016805 NEUROG1 NEUROG1 CCND2 CCND2 HES1 HES1 ENSPCTP00005015932 ENSPCTP00005015932 ENSPCTP00005015662 ENSPCTP00005015662
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPCTP00005000539annotation not available (286 aa)
ENSPCTP00005000780annotation not available (88 aa)
SMOC2SPARC-related modular calcium-binding protein 2 isoform X1. (457 aa)
EGFRReceptor protein-tyrosine kinase. (1208 aa)
APPAmyloid-beta precursor protein isoform X1. (770 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1. (957 aa)
SASS6LOW QUALITY PROTEIN: spindle assembly abnormal protein 6 homolog. (657 aa)
ENSPCTP00005002306annotation not available (184 aa)
ANXA1Annexin. (346 aa)
UBE2E2Ubiquitin-conjugating enzyme E2 E2 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
LSM11U7 snRNA-associated Sm-like protein LSm11. (360 aa)
KMT2EInactive histone-lysine N-methyltransferase 2E isoform X1. (1857 aa)
TMOD2Tropomodulin-3. (406 aa)
ANKRD17Ankyrin repeat domain-containing protein 17 isoform X3. (2589 aa)
PLRG1Pleiotropic regulator 1 isoform X1. (513 aa)
CDC7Cell division cycle 7-related protein kinase isoform X1. (574 aa)
LSM10U7 snRNA-associated Sm-like protein LSm10. (123 aa)
DTLDenticleless protein homolog isoform X1. (736 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
ENSPCTP00005005853annotation not available (96 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (142 aa)
ASNSAsparagine synthetase [glutamine-hydrolyzing] isoform X1. (561 aa)
TFDP1Transcription factor Dp-1 isoform X2. (457 aa)
RRM2BRibonucleoside-diphosphate reductase subunit M2 B. (351 aa)
CDC16Cell division cycle protein 16 homolog isoform X5. (620 aa)
USP22Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (522 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (358 aa)
FBXO5F-box only protein 5 isoform X1. (447 aa)
STOX1Storkhead-box protein 1 isoform X1. (989 aa)
MAD2L1BPMAD2L1-binding protein. (272 aa)
CDT1DNA replication factor Cdt1. (545 aa)
ENSPCTP00005009816annotation not available (83 aa)
NSMCE2E3 SUMO-protein ligase NSE2 isoform X1. (247 aa)
CDC25BM-phase inducer phosphatase 2 isoform X1. (574 aa)
MTA3Metastasis-associated protein MTA3. (594 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
RAD51CDNA repair protein RAD51 homolog 3 isoform X2. (371 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (983 aa)
MBLAC1Metallo-beta-lactamase domain-containing protein 1. (267 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (443 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CUL3Cullin-3; Belongs to the cullin family. (768 aa)
PRKCANon-specific serine/threonine protein kinase. (712 aa)
STAT5ASignal transducer and activator of transcription. (739 aa)
HSF1Heat shock factor protein 1 isoform X1. (553 aa)
ENSPCTP00005013982annotation not available (200 aa)
ENSPCTP00005014418annotation not available (199 aa)
POLDIP2Polymerase delta-interacting protein 2. (305 aa)
PPP1R10Serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1. (907 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
MTBPMdm2-binding protein isoform X3. (903 aa)
ENSPCTP00005031685annotation not available (290 aa)
CCDC57Coiled-coil domain-containing protein 57 isoform X1. (734 aa)
MECP2methyl-CpG-binding protein 2. (498 aa)
RCC2Protein RCC2. (501 aa)
ENSPCTP00005030601annotation not available (90 aa)
ANAPC11Anaphase-promoting complex subunit 11. (84 aa)
CUL4Bcullin-4B isoform X2; Belongs to the cullin family. (903 aa)
USP2Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (603 aa)
CUL4Acullin-4A isoform X1; Belongs to the cullin family. (761 aa)
CDK1Cyclin-dependent kinase 1 isoform X1; Belongs to the protein kinase superfamily. (297 aa)
MEIS2Homeobox protein Meis2 isoform X1. (477 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
RPTORRegulatory-associated protein of mTOR isoform X2. (1281 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ANAPC7LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (565 aa)
RRM1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (791 aa)
CDK4Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (303 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
DDX3XATP-dependent RNA helicase DDX3X isoform X1; Belongs to the DEAD box helicase family. (662 aa)
PHB2Prohibitin. (299 aa)
CENPJCentromere protein J isoform X2. (1347 aa)
PRAP1Proline-rich acidic protein 1. (145 aa)
NANOGHomeobox protein NANOG isoform X1. (318 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1 isoform X3. (1545 aa)
UBE2CUbiquitin-conjugating enzyme E2 C isoform X2; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CCDC57-2Coiled-coil domain-containing protein 57. (150 aa)
SIN3APaired amphipathic helix protein Sin3a isoform X1. (1274 aa)
KLHL18Kelch-like protein 18 isoform X3. (574 aa)
RB1Retinoblastoma-associated protein isoform X2. (929 aa)
BRCA2LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein. (3429 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E-binding protein 1. (137 aa)
CDC27Cell division cycle protein 27 homolog isoform X6. (831 aa)
CDC25AM-phase inducer phosphatase 1 isoform X1. (524 aa)
RAB11ARas-related protein Rab-11A isoform X2. (216 aa)
LOC114485722Cullin-4-like; Belongs to the cullin family. (233 aa)
SPHK1Sphingosine kinase 1. (391 aa)
CDC25CM-phase inducer phosphatase 3 isoform X1. (500 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
NKX3-1Homeobox protein Nkx-3.1. (158 aa)
RAD51BDNA repair protein RAD51 homolog 2 isoform X2. (278 aa)
ENSPCTP00005021490annotation not available (102 aa)
LGMNLegumain. (433 aa)
LOC112063320Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (102 aa)
SHBSH2 domain-containing adapter protein B isoform X4. (511 aa)
STILSCL-interrupting locus protein isoform X1. (1289 aa)
ENSPCTP00005020162annotation not available (439 aa)
MEPCE7SK snRNA methylphosphate capping enzyme. (697 aa)
CDCA5Sororin. (253 aa)
LOC112063118ATP-dependent RNA helicase DED1-like; Belongs to the DEAD box helicase family. (489 aa)
LOC112063121Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (838 aa)
ENSPCTP00005018845annotation not available (119 aa)
AIF1Allograft inflammatory factor 1. (147 aa)
RRM2Ribonucleoside-diphosphate reductase subunit M2 isoform X1. (408 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3 isoform X1. (676 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
HSPA2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa)
ENSPCTP00005016806annotation not available (216 aa)
ENSPCTP00005016805annotation not available (170 aa)
NEUROG1Neurogenin-1. (244 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
HES1Transcription factor HES-1. (280 aa)
ENSPCTP00005015932annotation not available (203 aa)
ENSPCTP00005015662annotation not available (82 aa)
Your Current Organism:
Physeter catodon
NCBI taxonomy Id: 9755
Other names: P. catodon, Physeter macrocephalus, sperm whale
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